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2201por Ravichandran, Rajeswari, Venugopal, Jayarama Reddy, Sundarrajan, Subramanian, Mukherjee, Shayanti, Ramakrishna, Seeram“…Myocardial infarction (MI) is characterized by heart-wall thinning, myocyte slippage, and ventricular dilation. The injury to the heart-wall muscle after MI is permanent, as after an abundant cell loss the myocardial tissue lacks the intrinsic capability to regenerate. …”
Publicado 2012
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2202por Kim, Yeung Jin, Chae, Soo Uk, Kim, Gang Deuk, Park, Kyung Hee, Lee, Yeum Sik, Lee, Hwang Yong“…As for the three subtypes of endplate depression, there were 20 cases of upper endplate depression, 12 cases of lower endplate depression and 11 cases of endplate slippage type. According to the examiners, there was a significant difference between being informed before and after the modified Yoshida's classification. …”
Publicado 2013
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2203“…Simple repeat patterns generated by DNA slippage tend to introduce length variations and point mutations in repeat regions. …”
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2204por Wauer, Tobias, Swatek, Kirby N, Wagstaff, Jane L, Gladkova, Christina, Pruneda, Jonathan N, Michel, Martin A, Gersch, Malte, Johnson, Christopher M, Freund, Stefan MV, Komander, David“…NMR reveals a second phosphoUb conformation in which β5-strand slippage retracts the C-terminal tail by two residues into the Ub core. …”
Publicado 2015
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2205“…The latter may be caused by a ternary complex (aminoacyl-tRNA*eEF1A*GTP) with a modification deficient tRNA inefficiently being accepted to the ribosomal A-site and thereby allowing an increased peptidyl-tRNA slippage and thus a frameshift error. In this study, we have investigated the role of wobble uridine modifications in reading frame maintenance, using either the Renilla/Firefly luciferase bicistronic reporter system or a modified Ty1 frameshifting site in a HIS4A::lacZ reporter system. …”
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2206por Albuquerque, Andreia“…Mild bleeding, pain, vaso-vagal symptoms, slippage of bands, priapism, difficulty in urination, anal fissure, and chronic longitudinal ulcers are normally considered minor complications, more frequently encountered. …”
Publicado 2016
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2207por Mittal, Karuna, Donthamsetty, Shashi, Kaur, Ramneet, Yang, Chunhua, Gupta, Meenakshi V, Reid, Michelle D, Choi, Da Hoon, Rida, Padmashree C G, Aneja, Ritu“…RESULTS: Docetaxel-induced polyploid cells undergo mitotic slippage and eventually spawn mononucleated cells via asymmetric cell division or neosis. …”
Publicado 2017
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2208“…Our assay removed the ambiguity of transcriptional slippage involvement in other frameshifting assays. …”
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2209por Jha, Sujata, Rollins, Madeline G., Fuchs, Gabriele, Procter, Dean J., Hall, Elizabeth A., Cozzolino, Kira, Sarnow, Peter, Savas, Jeffrey N., Walsh, Derek“…By converting human RACK1 to a charged, plant-like state, poxviruses remodel host ribosomes so that adenosine repeats erroneously generated by slippage of the viral RNA polymerase(4) confer a translational advantage. …”
Publicado 2017
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2210“…This alternative mechanism is based on Ca(2+)-slippage by a sarcoplasmatic reticulum Ca(2+)-ATPase (SERCA) and is controlled by the protein sarcolipin. …”
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2211por Figiel, Małgorzata, Krepl, Miroslav, Park, Sangwoo, Poznański, Jarosław, Skowronek, Krzysztof, Gołąb, Agnieszka, Ha, Taekjip, Šponer, Jiří, Nowotny, Marcin“…The latter results from rigidity of the poly(rA/dT) tract and leads to base-pair slippage of this sequence upon deformation into a catalytically relevant geometry. …”
Publicado 2018
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2212por Malek, Tanvirbanu J., Gandhi, Sahaj A., Barot, Vijay, Patel, Mukesh, Patel, Urmila H.“…There are nearly face-to-face directional specific π–π stacking interactions between the centroids of the nitrophenyl ring and the benzene ring of the 5-bromo-2-methoxy group [centroid–centroid distance = 3.6121 (5) Å and slippage = 1.115 Å], which also contributes to the molecular packing. …”
Publicado 2018
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2213por Aakko, Sofia, Straume, Anne Hege, Birkeland, Einar Elvbakken, Chen, Ping, Qiao, Xi, 'Lønning, Per Eystein', Kallio, Marko J.“…Notably, overexpression of the miR-203b-3p changed the fate of paclitaxel-treated breast and ovarian cancer cells from mitotic slippage to cell death. In breast tumors, high expression of the miR-203b-3p and MYC was associated with better therapy response and patient survival. …”
Publicado 2018
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2214“…All failures in group 1 occurred by knot slippage. The mode of failure in group 2 was tendon tearing in 5 of 6 cases. …”
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2215por Hosseini, Ardalan, Ghafoori, Elyas, Motavalli, Masoud, Nussbaumer, Alain, Zhao, Xiao-Ling, Koller, Roland“…Furthermore, neither slippage of the mechanical clamps nor any prestress loss in the CFRP plates was observed after 7.5 million fatigue cycles. …”
Publicado 2018
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2216por SHIMIZU, Satoru, OSAWA, Shigeyuki, KURODA, Hiroki, KOIZUMI, Hiroyuki, MOCHIZUKI, Takahiro, KUMABE, Toshihiro“…The thread of the HSS was secured with a clip to avoid slippage. For suturing side A, the clip pulling on the HSS was gently moved to the opposite side of side A, i.e. to side B, and the donor artery was revolved by several degrees to side B; the first stay suture was used as the fulcrum. …”
Publicado 2019
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2217“…This VPQ insertion is thought to be due to a nucleotide insertion of nine bases by slippage-like microindels. The predicted 3D structure of suncus leptin exhibited a typical four a-helix structure, however, the VPQ region protruded compared with human leptin. …”
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2218por Ogawa, Kaoru, Kurose, Akira, Kamataki, Akihisa, Asano, Kenichiro, Katayama, Kosuke, Kurotaki, Hidekachi“…Thus, significant DSBs in GC-GBM might be induced by an innate lesser stemness characteristic and be followed by mitotic slippage, resulting in polyploidization and the large pleomorphic nuclei. …”
Publicado 2019
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2219“…The mechanism of (CAG)n repeat generation, and related expandable repeat diseases in non-dividing cells, is currently understood in terms of a DNA template-based DNA repair synthesis process involving hairpin stabilized slippage, local error-prone repair via MutSβ (MSH2–MSH3) hairpin protective stabilization, then nascent strand extension by DNA polymerases-β and -δ. …”
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2220por Venta, Patrick J., Nguyen, Anthony K., Senut, Marie-Claude, Poulos, William G., Prukudom, Sukumal, Cibelli, Jose B.“…Although many dinucleotide short tandem repeat (diSTR) markers are available for this and similar purposes, they have certain disadvantages such as an excessive polymerase slippage (“stutter”) that causes difficulties in automated genotyping and cross-laboratory comparisons. …”
Publicado 2020
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