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2261“…Tandem Repeats (TRs) constitute a large class of repetitive sequences that are originated via phenomena such as replication slippage and are characterized by close spatial contiguity. …”
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2262por Herrera, Antonio, Martínez, Fernando, Iglesias, Daniel, Cegoñino, José, Ibarz, Elena, Gracia, Luis“…RESULTS: The mean loads to failure for each group were 295,44 N (Group 1; 9 × 23 screw), 564,05 N (Group 2; 9 × 28), 614,95 N (Group 3; 9 × 35), 651,14 N (Group 4; 10 × 28) and 664,99 (Group 5; 10 × 35). No slippage of the graft was observed in groups 3, 4 and 5. …”
Publicado 2010
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2263“…Selection contributes more strongly to the size and density distributions of SSR loci derived from EST library sequence than from BAC library sequence, although all SSRs likely are subject to similar physical and structural constraints, such as slippage of DNA replication machinery, that may generate increased allelic diversity in AT-rich sequence motifs. …”
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2264“…Eight B. vafer genes contain frameshifts in homopolymeric tracts that may be corrected by transcriptional slippage. Two of these encode DNA replication proteins: dnaX, which we infer is also frameshifted in B. floridanus, and dnaG. …”
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2265“…To explain these findings, a model is proposed in which disruption of the dystrophin-glycoprotein complex perturbs cell-extracellular matrix contacts and promotes the apparent slippage of myocytes past each other during LV distension. …”
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2266por Szydłowski, Konrad, Michalik, Maciej, Pawlak, Maciej, Bobowicz, Maciej, Frask, Agata“…Among other postoperative complications there were two incidents of band slippage, 2 patients had their port localization corrected and in one case drain disconnection occurred. …”
Publicado 2011
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2267“…Given their high abundance, and their capacity to expand in relatively short periods of time through replication slippage, they can greatly contribute to increase protein sequence space and generate novel protein functions. …”
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2268“…Most cells entered mitosis and then died, either during mitotic arrest or after mitotic slippage, or underwent endoreduplication. Next, we investigated whether inhibition of mTOR would prevent accumulation of cyclins and loss of mitotic competence in p21-arrested cells. …”
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2269por Álvarez, Mar, Barrioluengo, Verónica, Afonso-Lehmann, Raquel N., Menéndez-Arias, Luis“…The effects on frameshift fidelity were similar to those reported for mutation E89G and suggest that in HIV-1 group O RT, RNase H inactivation could affect template/primer slippage. Our results support a role for the RNase H domain during plus-strand DNA polymerization and suggest that mutations affecting RNase H function could also contribute to retrovirus variability during the later steps of reverse transcription.…”
Publicado 2013
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2270por van der Zee, Julie, Gijselinck, Ilse, Dillen, Lubina, Van Langenhove, Tim, Theuns, Jessie, Engelborghs, Sebastiaan, Philtjens, Stéphanie, Vandenbulcke, Mathieu, Sleegers, Kristel, Sieben, Anne, Bäumer, Veerle, Maes, Githa, Corsmit, Ellen, Borroni, Barbara, Padovani, Alessandro, Archetti, Silvana, Perneczky, Robert, Diehl-Schmid, Janine, de Mendonça, Alexandre, Miltenberger-Miltenyi, Gabriel, Pereira, Sónia, Pimentel, José, Nacmias, Benedetta, Bagnoli, Silvia, Sorbi, Sandro, Graff, Caroline, Chiang, Huei-Hsin, Westerlund, Marie, Sanchez-Valle, Raquel, Llado, Albert, Gelpi, Ellen, Santana, Isabel, Almeida, Maria Rosário, Santiago, Beatriz, Frisoni, Giovanni, Zanetti, Orazio, Bonvicini, Cristian, Synofzik, Matthis, Maetzler, Walter, vom Hagen, Jennifer Müller, Schöls, Ludger, Heneka, Michael T, Jessen, Frank, Matej, Radoslav, Parobkova, Eva, Kovacs, Gabor G, Ströbel, Thomas, Sarafov, Stayko, Tournev, Ivailo, Jordanova, Albena, Danek, Adrian, Arzberger, Thomas, Fabrizi, Gian Maria, Testi, Silvia, Salmon, Eric, Santens, Patrick, Martin, Jean-Jacques, Cras, Patrick, Vandenberghe, Rik, De Deyn, Peter Paul, Cruts, Marc, Van Broeckhoven, Christine“…Further, we observed a significantly increased frequency of short indels in the GC-rich low complexity sequence adjacent to the G(4)C(2) repeat in C9orf72 expansion carriers (P < 0.001) with the most common indel creating one long contiguous imperfect G(4)C(2) repeat, which is likely more prone to replication slippage and pathological expansion.…”
Publicado 2013
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2271“…The 3D scapular motion was measured using an optical tracking system, after minimizing reflective marker skin slippage using ultrasonography. The dynamic 3D motion of the scapula of dominant and nondominant shoulders, and the scapulohumeral rhythm (SHR) were analyzed at each 10° increment during the three planes of arm motion. …”
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2272por Zauber, Peter, Bishop, Timothy, Taylor, Claire, Sabbath-Solitare, Marlene, Marotta, Stephen, Tomlinson, Ian“…A single nucleotide substitution creates an oligo-adenine tract (A8) that appears to be inherently prone to further mis-pairing and slippage. The reported multiple tumor phenotype of carriers is not easily reconciled with molecular and population genetics data. …”
Publicado 2014
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2273por Nie, Hongyi, Liu, Chun, Cheng, Tingcai, Li, Qiongyan, Wu, Yuqian, Zhou, Mengting, Zhang, Yinxia, Xia, Qingyou“…To understand the pigment increase and alterations in pigment synthesis in q mutant, transcriptome profiles of the silkworm integument were investigated at 16 h after head capsule slippage in the fourth molt in q mutants and wild-type (Dazao). …”
Publicado 2014
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2274por Ghestem, Murielle, Cao, Kunfang, Ma, Wenzhang, Rowe, Nick, Leclerc, Raphaëlle, Gadenne, Clément, Stokes, Alexia“…One site was highly unstable, with severe soil slippage and erosion. The second site had been replanted 8 years previously and appeared to be physically stable. …”
Publicado 2014
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2275“…In the current VAT, there are drawbacks of poor test–retest reliability, slippage of the sensor at high-speed rotations, and limited data about the effect of aging. …”
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2276por Driscoll, Denise L., Chakravarty, Arijit, Bowman, Doug, Shinde, Vaishali, Lasky, Kerri, Shi, Judy, Vos, Tricia, Stringer, Bradley, Amidon, Ben, D'Amore, Natalie, Hyer, Marc L.“…Consistent with this wide array of functions for Plk1, the cellular consequences of Plk1 disruption are diverse, spanning delays in mitotic entry, mitotic spindle abnormalities, and transient mitotic arrest leading to mitotic slippage and failures in cytokinesis. In this work, we present the in vitro and in vivo consequences of Plk1 inhibition in cancer cells using potent, selective small-molecule Plk1 inhibitors and Plk1 genetic knock-down approaches. …”
Publicado 2014
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2277por Sproviero, Michael, Verwey, Anne M.R., Rankin, Katherine M., Witham, Aaron A., Soldatov, Dmitriy V., Manderville, Richard A., Fekry, Mostafa I., Sturla, Shana J., Sharma, Purshotam, Wetmore, Stacey D.“…Our experiments provide a basis for a model involving a two-base slippage and subsequent realignment process to relate the miscoding properties of C-linked C8-aryl-dG adducts with their chemical structures.…”
Publicado 2014
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2278“…The chains are linked via C=O⋯π [3.4316 (18) Å] and parallel slipped π–π interactions, involving inversion-related benzene rings [centroid–centroid distance = 3.8850 (14) Å; inter-planar distance = 3.3895 (10) Å; slippage = 1.899 Å], forming sheets lying parallel to (100).…”
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2279por OHTONARI, Tatsuya, NISHIHARA, Nobuharu, SUWA, Katsuyasu, OTA, Taisei, KOYAMA, Tsunemaro“…There was progression of slippage due to slight loosening in a case with lumbar degenerative spondylolisthesis, but this did not lead to exacerbation of the symptoms. …”
Publicado 2014
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2280por Yaldız, Can, Özdemir, Nail, Yaman, Onur, Feran, Hamit Günes, Tansug, Tugrul, Minoglu, Mustafa“…There was no instrumentation failure, loosening, or graft-related complication such as slippage or fracture of the graft. This approach demonstrated a good recovery rate of neurological functions and a high fusion rate.…”
Publicado 2015
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