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2301“…In particular, we highlighted the slippage of the monomeric components around the seam. …”
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2302por Su, Benyu, Lim, David, Tian, Zhujun, Liu, Guochao, Ding, Chenxia, Cai, Zuchao, Chen, Chen, Zhang, Fengmei, Feng, Zhihui“…Here we showed that in response to HU, the VPA significantly decreased the tumor cells survival, and promoted S-phase slippage, which was associated with the decrease of pCHK1 and WEE1/pCDK1-mediated checkpoint kinases phosphorylation pathway and inhibited pRPA2/Rad51-mediated HR repair pathway; the mutation of pRPA2 significantly diminished the above effect, indicating that VPA-caused HU sensitization was pRPA2 dependent. …”
Publicado 2021
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2303por Hu, Zhifeng, Kong, Haijuan, Tao, Lei, Qiao, Mengmeng, Yu, Dongzi, Lu, Feiyang, Dawelbeit, Ahmed, Yu, Muhuo“…The failure mode of the neat specimen included more Al–adhesive interface failure, while the NWCT specimen included more internal failure of adhesive–SCFs with the fracture, pullout, peeling, and slippage of SCFs improving the toughness and bonding strength of the adhesive layer. …”
Publicado 2021
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2304“…UBB(+1) is a mutated version of ubiquitin B peptide caused by a transcriptional frameshift due to the RNA polymerase II “slippage”. The accumulation of UBB(+1) has been linked to ubiquitin-proteasome system (UPS) dysfunction and neurodegeneration. …”
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2305“…Cellular deposits on the IOL surface (18.6%), cystoid macular edema (11.6%), subconjunctival haptic exposure (4.66%), and haptic slippage (2.33%) were the other complications. CONCLUSION: This method of trans-scleral IOL fixation is an effective rescue procedure for eyes with deficient capsular support when ophthalmologists perform in training.…”
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2306“…Treatment-related complications occurred in six treated feet (17.6%) including 13 cast slippages in five feet and one cast-related thigh abrasion. …”
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2307por Luo, Ming, Zhou, Gao-Yang, Shen, Han, Wang, Xin-Tian, Li, Mou-Cheng, Zhang, Zhong-Hua, Cao, Guang-Hui“…The reduced dislocation density, and greater number of grains amenable to slippage, produced less hydrogen transport and a lower crack sensitivity. …”
Publicado 2022
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2308Interface Mechanism and Splitting Characteristics of Fiber-Reinforced Cement-Solidified Aeolian Sandpor Zhang, Xiangdong, Pang, Shuai, Li, Jun, Zhang, Xuefeng, Cai, Guanjun, Tian, Lijun“…Although this improves the bonding force between the fiber and aeolian sand particles, the fibers are prone to fracture and slippage during the splitting process. The three-dimensional network structure formed by overlapping fibers is critical for the improvement of the splitting strength. …”
Publicado 2022
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2309por Pujari, Amar, Patil, Vinay, Chauhan, Nidhi, Thangavel, Rajeswari, Phuljhele, Swati, Saxena, Rohit“…Apart from normal muscles (n = 860, 93.68%), the location was identified in previously operated eyes (n = 54, 90%), in traumatic muscle slippage (n = 2, 11.11%), in ocular coat ectasia (n = 11, 91.66%), in thyroid muscle hypertrophy, in operated scleral fixated intraocular lens with strabismus, and other challenging cases. …”
Publicado 2022
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2310por Abihssira, Sharon, Bouche, Pierre-Alban, Cammas, Claire, Thirache, Clément, Nourissat, Geoffroy“…Knot failure mostly occurred by slippage, only with tapes. CONCLUSIONS: A suture-bridge construct with the non-post limb preserved and the post limb cut at a 4 mm distance from the knot provides with the best security. …”
Publicado 2022
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2311por Sleth, Camille, Bauzou, François, De Cristo, Claudia, Alkar, Fanny, Joly-Monrigal, Pauline, Jeandel, Clément, Cottalorda, Jérôme, Louahem M’Sabah, Djamel, Delpont, Marion“…Preoperative, immediate postoperative and final follow-up X-rays were evaluated to determine the degree of slippage, pin–joint ratio (PJR), neck–pin ratio (NPR), number of threads crossing the physis, neck–shaft angle (NSA), screw–physis angle and screw position in the physis. …”
Publicado 2022
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2312“…When the temperature exceeds 400 °C, the permeability of the oil shale is large, and it decreases approximately linearly with increasing pore pressure, which is attributed to the joint action of the gas slippage effect, adsorption effect, and effective stress. …”
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2313por El Din, Sayed M., Darvesh, Adil, Ayub, Assad, Sajid, Tanveer, Jamshed, Wasim, Eid, Mohamed R., Hussain, Syed M., Sánchez-Chero, Manuel, Ancca, Sheda Méndez, Ramírez Cerna, Johana Milagritos, Dapozzo, Carmen Luisa Aquije“…This article is novel in its sense that the influence of oblique magnetic force and second order velocity slippage on Carreau nano liquid and its numerical computation with help of the spectral relaxation method has never been done before. …”
Publicado 2022
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2314por Kalli, Sylvia, Vallieres, Cindy, Violet, Joseph, Sanders, Jan-Willem, Chapman, John, Vincken, Jean-Paul, Avery, Simon V., Araya-Cloutier, Carla“…The PM ABC transporter Yor1 and Lem3-dependent flippases conferred sensitivity and resistance, respectively, to the compounds, suggesting an important role for PM phospholipid asymmetry in their MoAs. …”
Publicado 2023
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2315por Inoue, Chiaki, Mukai, Kojiro, Matsudaira, Tatsuyuki, Nakayama, Jun, Kono, Nozomu, Aoki, Junken, Arai, Hiroyuki, Uchida, Yasunori, Taguchi, Tomohiko“…Knockdown of PPP1R12A increased the level of phosphorylated YAP, reduced that of YAP in the nucleus, and suppressed the transcription of CTGF (a YAP-regulated gene), reinforcing the role of PPP1R12A in YAP activation. ATP8A1 is a PS-flippase that concentrates PS in the cytosolic leaflet of the RE membrane and positively regulates YAP signalling. …”
Publicado 2023
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2316por Chaiyachati, Barbara H, Kaundal, Ravinder K, Zhao, Jiugang, Wu, Jie, Flavell, Richard, Chi, Tian“…RESULTS: We describe a simple method we have named LOFT [LoxP-flippase (FLP) recognition target (FRT) Trap], which is capable of reversible cKO and free of the limitations associated with existing techniques. …”
Publicado 2012
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2317por Croux, Christian, Nguyen, Ngoc-Phuong-Thao, Lee, Jieun, Raynaud, Céline, Saint-Prix, Florence, Gonzalez-Pajuelo, Maria, Meynial-Salles, Isabelle, Soucaille, Philippe“…RESULTS: The method used in this paper to knock-out or knock-in genes in C. acetobutylicum combines the use of an antibiotic-resistance gene for the deletion or replacement of the target gene, the subsequent elimination of the antibiotic-resistance gene with the flippase recombinase system from Saccharomyces cerevisiae, and a C. acetobutylicum strain that lacks upp, which encodes uracil phosphoribosyl-transferase, for subsequent use as a counter-selectable marker. …”
Publicado 2016
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2318por Kanmani, Paulraj, Albarracin, Leonardo, Kobayashi, Hisakazu, Hebert, Elvira Maria, Saavedra, Lucila, Komatsu, Ryoya, Gatica, Brian, Miyazaki, Ayako, Ikeda-Ohtsubo, Wakako, Suda, Yoshihito, Aso, Hisashi, Egusa, Shintaro, Mishima, Takashi, Salas-Burgos, Alexis, Takahashi, Hideki, Villena, Julio, Kitazawa, Haruki“…A typical EPS gene cluster was found in the TUA4408L genome consisting in five highly conserved genes epsA-E, and a variable region, which includes the genes for the polymerase wzy, the flippase wzx, and seven glycosyltransferases. In addition, we demonstrated here for the first time that L. delbrueckii TUA4408L and its EPS are able to improve the resistance of PIE cells against rotavirus infection by reducing viral replication and regulating inflammatory response. …”
Publicado 2018
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2319por Kang, Jee-Hae, Ko, Hyun-Mi, Han, Geum-Dong, Lee, Su-Young, Moon, Jung-Sun, Kim, Min-Seok, Koh, Jeong-Tae, Kim, Sun-Hun“…Among the investigated lipid transporter proteins, floppases (Abcb4, Abcc5, and Abcg1) were upregulated, whereas flippases (Atp11c and Atp8a1) downregulated during osteoclastogenesis. …”
Publicado 2020
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2320por Rebendenne, Antoine, Roy, Priyanka, Bonaventure, Boris, Chaves, Valadão Ana Luiza, Desmarets, Lowiese, Rouillé, Yves, Tauziet, Marine, Arnaud-Arnould, Mary, Giovannini, Donatella, Lee, Yenarae, DeWeirdt, Peter, Hegde, Mudra, Garcia de, Gracia Francisco, McKellar, Joe, Wencker, Mélanie, Dubuisson, Jean, Belouzard, Sandrine, Moncorgé, Olivier, Doench, John G., Goujon, Caroline“…In addition to identifying ACE2 and TMPRSS2 as top hits, our study reveals a series of so far unidentified and critical host-dependency factors, including the Adaptins AP1G1 and AP1B1 and the flippase ATP8B1. Moreover, new anti-SARS-CoV-2 proteins with potent activity, including several membrane-associated Mucins, IL6R, and CD44 were identified. …”
Publicado 2021
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