“…These antibiotics inhibit lipid II flippase and potentiate β-lactam activity against methicillin-resistant Staphylococcus aureus in mice, potentially providing a new treatment regimen.…”
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“…The overall complication rate is 10–20% and the most common complication is of ‘slippage’. Although other complications such as gastric band migration and erosion have been reported, the phenomenon of a migrated gastric band connecting tube eroding into the colon (after port removal) is seldom reported in the literature. …”
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“…The upstream boundary of the signal consists of the sequence UUUAAAC, which is the likely site of ribosomal slippage. We show by creation of complementary nucleotide changes that the RNA downstream of this “slippery” sequence folds into a tertiary structure termed a pseudoknot, the formation of which is essential for efficient frameshifting.…”
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“…The advantages of the technique are that the residual cam-type deformity caused by the slippage can be corrected and reconstructed reliably and reproducibly before distracting the hip joint; and radiation with fluoroscopy is used for only definitive reduction and reconstruction, which is obtained with cannulated screws. …”
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“…In the crystal structure, there are π–π stacking inter­actions between symmetry-related benzene rings with a centroid–centroid distance of 3.7305 (13) Å, a perpendicular distance between the planes of 3.2851 (9) Å and a slippage of 1.768 Å. The structure is further stabilized by weak inter­molecular C—H⋯O hydrogen bonds.…”
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“…The crystal structure also exhibits a slipped π–π inter­action between the furan rings of neighbouring mol­ecules [centroid–centroid distance = 3.719 (2) Å, inter­planar distance = 3.475 (2) Å and slippage = 1.325 Å].…”
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“…The crystal structure is stabilized by an aromatic π–π stacking inter­action between the phenyl rings of neighbouring mol­ecules [centroid–centroid distance = 3.772 (2) Å, inter­planar distance = 3.546 (2) Å and slippage = 1.286 (2) Å].…”
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“…The crystal structure also exhibits a slipped π–π inter­action between the furan and benzene rings of neighboring mol­ecules [centroid–centroid distance = 3.743 (2) Å, inter­planar distance = 3.543 (2) Å and slippage = 1.207 (2) Å].…”
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“…These dimers are further stabilized by weak inter­molecular C—H⋯π inter­actions, and by slipped π–π inter­actions between the furan rings of adjacent mol­ecules [centroid–centroid distance = 3.557 (2) Å, inter­planar distance = 3.301 (2) Å and slippage = 1.325 (2) Å].…”
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“…In addition, there exist two different offset π–π stacking inter­actions between benzene rings and between naphthalene systems of symmetry-related mol­ecules [centroid–centroid distances = 3.876 (9) and 3.566 (4) Å, and slippage = 1.412 and 0.554 Å, respectively.…”
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“…These dimers are connected by slipped π–π inter­actions between the benzene rings of neighbouring mol­ecules [centroid–centroid distance = 3.671 (3) Å and slippage = 1.049 (3) Å].…”
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“…Unfortunately, post-operative events such as breakdown of the wrap, downward slippage, or transdiaphragmatic herniation of an intact wrap cause these procedures to fail and create complications such as recurrent hiatal hernia and reflux dysphagia, regurgitation, and obstruction requiring revision surgery. …”
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“…We isolate this prospective mutual productivity beyond the Standard Model in the framework of the supersymmetric No-Scale Flipped $SU$(5) grand unified theory, supplemented with extra vector-like matter (flippons). Evident overproduction is observed in three CMS \mt2 and four ATLAS hadronic and multijet signal regions, where a \x2 fitting procedure of the CMS 5 \fb \mt2 search establishes a best fit SUSY mass in sharp agreement with corresponding ATLAS searches of equivalently heightened signal significance. …”
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“…Finally, the recent discovery of no less than three different categories of LipidII flippases will be discussed.…”
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“…Ectopic PS exposure via phospholipid flippase knockout and scramblase overexpression induced PS exposure preferentially at distal dendrites and caused distinct modes of neurite loss that differ in larval sensory dendrites and in adult olfactory axons. …”
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“…Removal of selective markers via flippase recombinase was successful across integrated loci except for those targeted to the native URA3 locus, suggesting that the genome sequence or structure alters the efficacy of this system.…”
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“…We herein report the synthesis and biological and computational evaluation of 12 linear analogues of the cyclic lipopeptide battacin, enabled by Cysteine Lipidation on a Peptide or Amino Acid (CLipPA) technology. Several of the novel “CLipP”ed lipopeptides exhibited low micromolar MICs and MBCs against both Gram-negative and Gram-positive bacteria. …”
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“…(ii) This index forecasts the slippage in efficiency earlier than other known metrics. …”
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“…Surface skin deformation of the finger pad during partial slippage at finger–object interfaces elicits firing of the tactile sensory afferents. …”
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“…Based on the failure mechanism of steeply dipping discontinuities, the ground movement mechanism was proposed considering the horizontal in situ ground stress and caved rock mass: slippage of fault F3, slippage of fault F4, and toppling of rock columns. …”
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