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1961por Bayer, Ilker S.“…Alone or in conjunction with other sensors, MEMS platforms are considered very promising for robots to detect the contact forces, slippage and the distance to the objects for effective dexterous manipulation. …”
Publicado 2022
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1962por Bruekner, Susanne R, Pieters, Wietske, Fish, Alexander, Liaci, A Manuel, Scheffers, Serge, Rayner, Emily, Kaldenbach, Daphne, Drost, Lisa, Dekker, Marleen, van Hees-Stuivenberg, Sandrine, Delzenne-Goette, Elly, de Konink, Charlotte, Houlleberghs, Hellen, Dubbink, Hendrikus Jan, AlSaegh, Abeer, de Wind, Niels, Förster, Friedrich, te Riele, Hein, Sixma, Titia K“…Characterization of the mutant in mouse models, as well as slippage and repair assays, shows a mildly pathogenic phenotype. …”
Publicado 2023
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1963por Ottonello, Alessandra, Wyllie, Jessica A., Yahiaoui, Oussama, Sun, Shoujun, Koelln, Rebecca A., Homer, Joshua A., Johnson, Robert M., Murray, Ewan, Williams, Paul, Bolla, Jani R., Robinson, Carol V., Fallon, Thomas, Soares da Costa, Tatiana P., Moses, John E.“…Further, evidence suggests that the shapeshifting ligands destabilize the complex formed between the flippase MurJ and lipid II, implying the potential for a new mode of action for polyvalent glycopeptides. …”
Publicado 2023
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1964“…U.S.A. 74, 1821–1825 (1977)] but the identity of the putative PE flippase has eluded discovery. Recently, members of the DedA superfamily have been implicated in flipping the bacterial lipid carrier undecaprenyl phosphate and in scrambling eukaryotic phospholipids in vitro. …”
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1965por Adnan, Muhammad, Islam, Waqar, Waheed, Abdul, Hussain, Quaid, Shen, Ling, Wang, Juan, Liu, Gang“…This recycling process requires several components, including a phospholipid flippase (Drs2-Cdc50), an F-box protein (Rcy1), a sorting nexin (Snx4-Atg20), a retromer submit, and the COPI coat complex. …”
Publicado 2023
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1966por Lee, Chang-Lung, Moding, Everett J., Huang, Xiaofang, Li, Yifan, Woodlief, Loretta Z., Rodrigues, Rafaela C., Ma, Yan, Kirsch, David G.“…To overcome this limitation, we inserted FRT (flippase recognition target) sites flanking exons 2–6 of the endogenous p53 gene in mice to generate a p53(FRT) allele that can be deleted by Flp recombinase. …”
Publicado 2012
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1967“…A temperature sensitive plasmid containing arabinose inducible lambda Red recombineering genes and a rhamnose inducible flippase recombinase was constructed to facilitate fast marker-free deletions. …”
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1968por Benedikter, Birke J., Weseler, Antje R., Wouters, Emiel F. M., Savelkoul, Paul H. M., Rohde, Gernot G. U., Stassen, Frank R. M.“…In this review article, we discuss targets of redox-dependent thiol modifications that are known or expected to be involved in the regulation of EV release, namely redox-sensitive calcium channels, N-ethylmaleimide sensitive factor, protein disulfide isomerase, phospholipid flippases, actin filaments, calpains and cell surface-exposed thiols. …”
Publicado 2018
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1969por Ahmad, Mudassar, Winkler, Christine M., Kolmbauer, Markus, Pichler, Harald, Schwab, Helmut, Emmerstorfer‐Augustin, Anita“…Excision of the marker is mediated by Flippase (Flp) recombinase and occurs at high frequency (≥95%). …”
Publicado 2019
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1970“…The “eat me” signal of this event is thought to be the translocation of phosphatidylserine from the inner to the outer membrane leaflet due to activation of the scramblase, while the flippase is inactivated. Both processes are triggered by an increased intracellular Ca(2+) concentration. …”
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1971por Oh, Jun-Young, Han, Jeong-Ho, Lee, Hyoeun, Han, Young-Eun, Rah, Jong Cheol, Park, Hyungju“…This system, called “cFork (see fork)”, includes delivering serotype 1-packaged AAV vectors (AAV1s) containing Cre or flippase recombinase (FlpO) into two different presynaptic brain areas, and AAV5 with a dual gene expression cassette in postsynaptic neurons. …”
Publicado 2020
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1972por Raiders, Stephan, Black, Erik Calvin, Bae, Andrea, MacFarlane, Stephen, Klein, Mason, Shaham, Shai, Singhvi, Aakanksha“…The phosphatidylserine (PS) flippase TAT-1/ATP8A functions with glial PS-receptor PSR-1/PSR and PAT-2/α-integrin to initiate engulfment. …”
Publicado 2021
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1973“…In this review, we discuss how combined action of PS biosynthesis enzymes in the endoplasmic reticulum (ER), lipid transfer proteins (LTPs) acting within membrane contact sites (MCS) between the ER and other compartments, and lipid flippases and scramblases that mediate PS flip-flop between membrane leaflets controls the cellular distribution of PS. …”
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1974“…To address this issue, we attempted to identify a potential transporter of plasmalogens from the outer to the inner leaflet of plasma membrane by focusing on phospholipid flippases, type-IV P-type adenosine triphosphatases (P4-ATPase), localized in the plasma membranes. …”
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1975por Wieczorek, Alicja, Sendobra, Anna, Maniyeri, Akshey, Sugalska, Magdalena, Klein, Gracjana, Raina, Satish“…Interestingly, LapD absence results in the substantial retention of LPS in the inner membranes and synthetic lethality when either the lauroyl or the myristoyl acyl transferase is absent, which can be overcome by single-amino acid suppressor mutations in LPS flippase MsbA, suggesting LPS translocation defects in ΔlapD bacteria. …”
Publicado 2022
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1976“…Furthermore, we find that loss of the phospholipid flippase subunit TMEM30A impairs the plasma membrane trafficking of its binding partner, the P4-type ATPase ATP11B, and depletion of TMEM30A or ATP11B disrupts plasma membrane asymmetry and promotes resistance to C6-Cer toxicity. …”
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1977“…We present a new representation for the level-crossing probability, PLSZ = exp(–kappan[script G]n), which allows a simple numerical evaluation of PLSZ in both the resonant and nonresonant cases, and where [script G]n contains the full dependence of PLSZ on the mixing angle theta. …”
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1978“…We present a new representation for the level-crossing probability, $P_{LZ}=\exp(-\kappa_n\G_n)$, which allows a simple numerical evaluation of $P_{LZ}$ in both the resonant and non-resonant cases and where $\G_n$ contains the full dependence of $P_{LZ}$ on the mixing angle $\theta$. …”
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1979“…INTRODUCTION: Spondyloptosis, characterized by complete slippage of the upper vertebral body relative to the lower vertebral body, is an exceedingly rare condition. …”
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1980por Aoyama, Natsu, Kanematsu, Hideyuki, Barry, Dana M., Miura, Hidekazu, Ogawa, Akiko, Kogo, Takeshi, Kawai, Risa, Hagio, Takeshi, Hirai, Nobumitsu, Kato, Takehito, Yoshitake, Michiko, Ichino, Ryoichi“…Some bacteria that form biofilms cause periodontal disease, corrosion of the metal materials that make up drains, and slippage. Inside of a biofilm is an environment conducive to the growth and propagation of bacteria. …”
Publicado 2023
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