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641por Mo, Yuqing, Ye, Ling, Cai, Hui, Zhu, Guiping, Wang, Jian, Zhu, Mengchan, Song, Xixi, Yang, Chengyu, Jin, Meiling“…BACKGROUND: Serine peptidase inhibitor, clade B, member 10 (SERPINB10) contributes to allergic inflammation in asthma. …”
Publicado 2021
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642“…BACKGROUND: Polo-like kinases (PLKs) are conserved serine/threonine kinases that regulate the cell cycle. …”
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643por Scheaffer, Hannah L., Borazjani, Abdolsamad, Szafran, Brittany N., Ross, Matthew K.“…Further, THP-1 monocytes with normal CES1 expression (control cells) and “knocked-down” CES1 expression (CES1KD cells) were employed to confirm CES1’s role in PGD(2)-G catabolism. …”
Publicado 2020
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644por He, Cuiying, Liu, Beichen, Wang, Huan-You, Wu, Lili, Zhao, Guimin, Huang, Chen, Liu, Yueping, Shan, Baoen, Liu, Lihong“…BACKGROUND: Increasing evidence has convincingly shown that abnormal pre-mRNA splicing is implicated in the development of most human malignancies. Serine/arginine-rich protein kinase 1 (SRPK1), a key splicing regulator, is reported to be overexpressed in leukemia and other cancer types, which suggests the therapeutic potential of targeting SRPK1. …”
Publicado 2022
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645por Fang, Jiankang, Zhao, Xia, Li, Shuai, Xing, Xingan, Wang, Haitao, Lazarovici, Philip, Zheng, Wenhua“…Additionally, when the upstream activator KRAS was knocked down by siRNA, the protective effect of artemisinin was also blocked. …”
Publicado 2019
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646por Hofstetter, Julia, Ogunleye, Ayoola, Kutschke, André, Buchholz, Lisa Marie, Wolf, Elmar, Raabe, Thomas, Gallant, Peter“…This beneficial effect is still observed when Spt5 is knocked down systemically and after tumor initiation, highlighting SPT5 as a potential drug target in human oncology.…”
Publicado 2023
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647por Tian, Yi, Xiao, Xinqiang, Gong, Xing, Peng, Feng, Xu, Yun, Jiang, Yongfang, Gong, Guozhong“…Taken together, we presented here a novel cross-talk between miR-181a and PTEN which was raised by HBx, and this shined a new line in HBV-related hepato-carcinogenesis.…”
Publicado 2017
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648“…Treatment with MBZ induced shrinking of ECs and caused G2-M arrest and apoptosis with an increased Sub-G1 fraction. …”
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649por Li, Tingting, Zhao, Gaihong, Zhang, Taoqing, Zhang, Zhaoxia, Chen, Xin, Song, Jie, Wang, Xiao, Li, Jiangnan, Huang, Li, Wen, Lili, Li, Changyao, Zhao, Dongming, He, Xijun, Bu, Zhigao, Zheng, Jun, Weng, Changjiang“…African swine fever (ASF) is a severe hemorrhagic disease in swine characterized by massive lymphocyte depletion and cell death, with apoptosis and necrosis in infected lymphoid tissues. …”
Publicado 2021
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