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  1. 6501
    “…TGCT is synonymous with pigmented villonodular synovitis (PVNS). We describe the unique case of a 56-year-old obese male with type 2 diabetes who had polymicrobial septic arthritis of his left knee joint with concurrent D-TGCT in the same knee. …”
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    Diffuse-Type Tenosynovial Giant Cell Tumor of the Knee with Concurrent Polymicrobial Infection (Klebsiella oxytoca and Group B Streptococcus)
  2. 6502
    “…OBJECTIVE: Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease characterized by inflammatory synovitis. We developed a new disease activity evaluation system using important cytokines to help doctors better evaluate disease activity in patients with RA. …”
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    Decision tree analysis for evaluating disease activity in patients with rheumatoid arthritis
  3. 6503
    “…The patient presented with seizures and was found to have a brain infarct, cavitary lung lesions, synovitis of the knee, multiple skin lesions, and chorioretinitis. …”
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    Pandora’s Box: Disseminated Coccidioidomycosis Associated with Self-Medication with an Unregulated Potent Corticosteroid Acquired in Mexico
  4. 6504
    “…Rheumatoid arthritis (RA) is one of the most common autoimmune diseases that affect synovitis, bone, cartilage, and joint. RA leads to bone and cartilage damage and extra-articular disorders. …”
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    Functional Interactions Between lncRNAs/circRNAs and miRNAs: Insights Into Rheumatoid Arthritis
  5. 6505
    “…MRI remains the gold standard in imaging intra-articular soft tissue pathology and should be the study of choice in differentiating intra-articular lipomas from similar conditions such as pigmented villonodular synovitis and lipoma arborescens.…”
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    A Rare Presentation of a True Intra-articular Lipoma: A Case Report and Review of Imaging Findings
  6. 6506
    “…In MARS MRI, the incidence of bone destruction, lamellar synovitis, and extracapsular soft tissue oedema were significantly higher in PJI than in non-PJI. …”
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    Metal Artifact Reduction Sequences MRI: A Useful Reference for Preoperative Diagnosis and Debridement Planning of Periprosthetic Joint Infection
  7. 6507
    “…The pathological features of OA are the erosion of articular cartilage, subchondral bone sclerosis, synovitis, and metabolic disorder. Its progression is characterized by aberrant expression of genes involved in inflammation, proliferation, and metabolism of chondrocytes. …”
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    RNA binding proteins in osteoarthritis
  8. 6508
    “…TP-VP NPs effectively down-regulated IL-1β, IL-6 and TNF-α levels to inhibit the erosion of synovitis and bone tissue, and alleviate the swelling and deformation of CIA mice’s feet. …”
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    Triptolide and l-ascorbate palmitate co-loaded micelles for combination therapy of rheumatoid arthritis and side effect attenuation
  9. 6509
    “…Finally, the synovial and bone compartment are targeted by specific autoantibodies against modified antigens, initiating a local inflammatory response that will eventually culminate in clinically evident synovitis. In this review, we discuss the elaborate disease mechanisms in place during preclinical RA, providing a broad perspective in the light of current evidence.…”
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    Disease mechanisms in preclinical rheumatoid arthritis: A narrative review
  10. 6510
    “…Rheumatoid arthritis belongs to the group of chronic systemic autoimmune diseases characterized by the development of destructive synovitis and extra-articular manifestations. Cytokines regulate a wide range of inflammatory processes involved in the pathogenesis of rheumatoid arthritis and contribute to the induction of autoimmunity and chronic inflammation. …”
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    Atomic Simulation of the Binding of JAK1 and JAK2 with the Selective Inhibitor Ruxolitinib
  11. 6511
    “…Activated fibroblast-like synoviocytes (FLSs) play an essential role in synovitis formation and joint destruction in RA. The Hedgehog signaling pathway is aberrantly activated and contributes to the aggressive phenotype of RA-FLSs. …”
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    Chemically modified small interfering RNA targeting Hedgehog signaling pathway for rheumatoid arthritis therapy
  12. 6512
    “…Numerous studies have shown that MSUS is more sensitive than clinical examination for detecting subclinical synovitis. MSUS is a well-accepted tool, easily accessible and non-irradiating. …”
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    Contribution of Ultrasound in Current Practice for Managing Juvenile Idiopathic Arthritis
  13. 6513
    “…Both humoral and cellular mediators contribute to cartilage destruction, abnormal bone remodeling, synovitis, and joint effusion. The increasing prevalence of this disease has led to a growing interest in using animal models as the primary way to broaden the knowledge of the pathogenesis of OA and possible therapies at each stage of disease development. …”
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    Osteoarthritis: Pathogenesis, Animal Models, and New Regenerative Therapies
  14. 6514
    “…Synovitis-acne-pustulosis-hyperostosis-osteitis (SAPHO) syndrome is a rare disease with an unknown entity that affects the skin and the peripheral and/or axial joints. …”
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    SAPHO Syndrome Complicated by Lesions of the Central Nervous System Successfully Treated with Brodalumab
  15. 6515
    “…Bogolyubov Conference in Moscow, Dubna and Kyiv. N.N.Bogoliubov Prize for Young Scientists. …”
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    Articles in this issue, v.4
  16. 6516
    por Laverty, Ursula, Benson, Claire
    Publicado 2019
    “…INTRODUCTION: This is a complex case of a 50-year-old lady who presented with peripheral synovitis, fever and rash. She developed ulcerative skin lesions, proximal muscle weakness and pulmonary fibrosis. …”
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    7. Anti-MDA5 associated dermatomyositis
  17. 6517
    “…The average synovitis score was lower in early FAI than late FAI (2.5 ± 1.7, 4.4 ± 1.6; p=0.0086). …”
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    Intraarticular Inflammation and Catabolic Markers in Femoroacetabular Impingement during Progression of Disease -comparison between early and late stage disease-
  18. 6518
    “…Holland, MD, Aridis: Advisor/Consultant|Basilea Pharmaceutica: Advisor/Consultant|Karius: Advisor/Consultant|Lysovant: Advisor/Consultant Sara E. Cosgrove, MD, Basilea: Advisor/Consultant|Debiopharma: Advisor/Consultant Sarah B. …”
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    LB2302. Ceftobiprole Compared to Daptomycin With or Without Optional Aztreonam for the Treatment of Complicated Staphylococcus aureus (SAB): Results of a Phase 3, Randomized, Double-Blind Trial (ERADICATE)
  19. 6519
    “…Outcome measures included the ASMI labral repair outcomes questionnaire, ASES scoring system, overhead athlete shoulder and elbow score, KJOC, and the veterans rand 12 item health survey (VR-12). …”
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    Biceps Tenodesis in Pitchers
  20. 6520
    “…Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by chronic synovitis and the destruction of bones and joints. …”
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    Elucidating a fresh perspective on the interplay between exosomes and rheumatoid arthritis
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