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6781por You, Hongqin, Dang, Guanglei, Lu, Bichao, Zhang, Siya, Li, Chen, Wang, Lun, Hu, Yu, Chen, Hui, Zhang, Jianmin, He, Wei“…SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) syndrome shows a wide variability in musculoskeletal and cutaneous manifestations, and it is therefore underrecognized and misdiagnosed in the clinic due to a lack of specific markers. …”
Publicado 2021
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6782por Oliviero, Francesca, Galozzi, Paola, Scanu, Anna, Galuppini, Francesca, Lazzarin, Vanni, Brocco, Silvia, Ravagnan, Giampietro, Sfriso, Paolo, Ramonda, Roberta, Spinella, Paolo, Punzi, Leonardo, Pennelli, Gianmaria, Luisetto, Roberto“…Secondary outcomes such as leukocyte infiltration, necrosis, edema, and synovitis were also decreased. PD caused a reduction in circulating levels of IL-1ß and CXCL1, as well as their tissue expression. …”
Publicado 2021
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6783“…Rheumatoid arthritis (RA) acts as one of the most common, agnogenic and chronic inflammatory-autoimmune disorder which is characterized by persistent synovitis, cartilage destruction, and joint deformities, leads to a wide range of disabilities, and increased mortality, thus imposing enormous burdens. …”
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6784por Niaki, Omid Zahedi, Gunesekera, Nicole, Lian, Christine, Vleugels, Ruth Ann, Scott, Deborah A.“…She was noted to have associated synovitis of the hands and wrists bilaterally and was started on celecoxib. …”
Publicado 2021
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6785“…OBJECTIVE: Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a rare chronic inflammatory disorder and the underlying pathogenesis is unclear. …”
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6786por Cheng, Jai-Hong, Yen, Ke-Tien, Chou, Wen-Yi, Jhan, Shun-Wun, Hsu, Shan-Ling, Ko, Jih-Yang, Wang, Ching-Jen, Kuo, Chun-En Aurea, Wu, Szu-Ying, Hsu, Tsai-Chin, Hsu, Chieh-Cheng“…ADSC2 combined with SW therapy significantly reduced the synovitis score and OARSI score in comparison with other treatments. …”
Publicado 2021
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6787por Vacchi, Caterina, Manfredi, Andreina, Cassone, Giulia, Cerri, Stefania, Della Casa, Giovanni, Andrisani, Dario, Salvarani, Carlo, Sebastiani, Marco“…Rheumatoid arthritis (RA) is a chronic systemic inflammatory disease characterized by chronic symmetrical erosive synovitis and extra-articular manifestations, including interstitial lung disease (ILD), whose treatment is nowadays challenging due to high infectious risk and possible pulmonary iatrogenic toxicity. …”
Publicado 2021
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6788“…This is mainly due to conventional diagnostic tools, such as MRI, producing ambiguous results versus pigmented villonodular synovitis (PVNS) and ganglion cysts. CASE PRESENTATION: Here we report an individual in their late-20s with a gouty tophus located at the origin of the ACL in the knee. …”
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6789por Tsai, Chang-Youh, Hsieh, Song-Chou, Liu, Chih-Wei, Lu, Cheng-Hsun, Liao, Hsien-Tzung, Chen, Ming-Han, Li, Ko-Jen, Wu, Cheng-Han, Shen, Cheih-Yu, Kuo, Yu-Min, Yu, Chia-Li“…Rheumatoid arthritis (RA) is a typical autoimmune-mediated rheumatic disease presenting as a chronic synovitis in the joint. The chronic synovial inflammation is characterized by hyper-vascularity and extravasation of various immune-related cells to form lymphoid aggregates where an intimate cross-talk among innate and adaptive immune cells takes place. …”
Publicado 2021
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6790“…Osteoarthritis (OA), the most common form of human joint disease, is characterized by progressive degeneration of the articular cartilage, synovitis and subchondral osteoporosis. Chondrocyte apoptosis is the primary pathogenic mechanism of OA and is considered to be a potential therapeutic target. …”
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6791por Di Matteo, Andrea, Smerilli, Gianluca, Cipolletta, Edoardo, Salaffi, Fausto, De Angelis, Rossella, Di Carlo, Marco, Filippucci, Emilio, Grassi, Walter“…The US is particularly helpful for the detection of joint and/or tendon inflammation in patients with arthralgia but without clinical synovitis, and for the early identification of bone erosions. …”
Publicado 2021
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6792por Chen, Xiaochen, Lin, Haofeng, Chen, Jinyang, Wu, Lisheng, Zhu, Junqing, Ye, Yongnong, Chen, Shixian, Du, Hongyan, Li, Juan“…Moreover, PTX alleviated synovitis and bone destruction in CIA mice. In conclusion, PTX inhibits the migration and inflammatory mediator production of RA-FLS by targeting the MAPK and AKT/mTOR signaling pathways, which provides an experimental basis for the potential application in the treatment of RA.…”
Publicado 2021
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6793“…This anti-inflammatory effect was also confirmed histologically to attenuate synovitis and neutrophil infiltration. We demonstrated that BV markedly ameliorated ankle edema and mechanical allodynia in gouty rats. …”
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6794“…CONCLUSION: This correlation may suggest that pain intensity is associated with widened capsular width because of joint effusion or synovitis. Further studies are required to refine and establish the protocols for standard examinations using ultrasound imaging. …”
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6795“…BACKGROUND: Osteoarthritis (OA) is the most common chronic degenerative joint disorder globally that is characterized by synovitis, cartilage degeneration, joint space stenosis, and sub-cartilage bone hyperplasia. …”
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6796por Chen, Yumei, Ma, Chiyu, Liu, Lixiong, He, Jingquan, Zhu, Chengxin, Zheng, Fengping, Dai, Weier, Hong, Xiaoping, Liu, Dongzhou, Tang, Donge, Dai, Yong“…Rheumatoid arthritis (RA) is an autoimmune disease described by joint destruction, synovitis and pannus formation. The gut microbiota acts as an environmental factor that plays an important role in RA, but little research regarding the etiopathogenic mechanisms of the microbiome in RA has been carried out. …”
Publicado 2021
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6797por García-Marín, Luis M., Campos, Adrián I., Cuéllar-Partida, Gabriel, Medland, Sarah E., Kollins, Scott H., Rentería, Miguel E.“…Our results reveal that genetic variants associated with iron deficiency anemia (ICD10), obesity, type 2 diabetes, synovitis and tenosynovitis (ICD10), polyarthritis (ICD10), neck or shoulder pain, and substance use in adults display partial genetic causality on ADHD risk in children. …”
Publicado 2021
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6798“…We concluded that incidence of synovitis knee along with raised markers of inflammation, that is, C-reactive protein, erythrocyte sedimentation rate, and synovial fluid TNF-α levels was significantly higher in Stage II of OA knee, indicating that inflammation is significant part of early OA knee. …”
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6799“…METHODS: Potential studies in English language published in Medline/PubMed, Scopus and Google Scholar since 2000 were searched by using keywords such as osteoarthritis, statins, progression, treatment, prevalence, synovitis, pain. Fourteen papers were found to be relevant and were summarised. …”
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6800“…Imaging technology has evolved to allow us to better study psoriatic disease and define disease activity, including synovitis and enthesitis. Enthesitis is implicated in the pathogenesis, diagnosis and prognosis of PsA. …”
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