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  1. 6801
    “…However, IL-27 promotes Th1 cell differentiation, which may exacerbate RA synovitis. Moreover, IL-27 also acts on RA synovial fibroblasts (RA-FLSs) and regulatory T cells (Tregs), but some of its functions are unclear. …”
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    Interleukin 27 Signaling in Rheumatoid Arthritis Patients: Good or Evil?
  2. 6802
    “…Both male and female rats showed comparable degenerative changes to the LPA-treated knee including chondrocyte death, focal bone erosion, and synovitis. Mechanical withdrawal thresholds decreased by 20-30% indicative of secondary allodynia in the affected limb; however, there was no significant difference in pain sensitivity between the sexes. …”
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    Joint Damage and Neuropathic Pain in Rats Treated With Lysophosphatidic Acid
  3. 6803
    “…The review also explores the progress and challenges with the use of stimuli-responsive nanomaterials to manage inflammatory arthritis based on pathological changes, including cartilage degeneration, synovitis, and subchondral bone destruction. Exposure to appropriate stimuli induced by such histopathological alterations can trigger the release of therapeutic medications, imperative in the joint-targeted treatment of inflammatory arthritis.…”
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    Advanced application of stimuli-responsive drug delivery system for inflammatory arthritis treatment
  4. 6804
    por Shon, Oog-Jin, Lee, In Jun, Kim, Gi Beom
    Publicado 2022
    “…BACKGROUND: This article introduces a novel open synovectomy technique using an arthroscopy shaver blade to effectively remove intra-articular synovitis during revision surgery for infected primary total knee arthroplasty. …”
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    A novel open synovectomy technique using an arthroscopy shaver blade in revision surgery to treat infected total knee arthroplasty: a technical note
  5. 6805
    “…Based on these findings, we propose a viable cell-free alternative to MSC-based therapeutics as an alternative approach to treating synovitis and IFP fibrosis.…”
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    Human infrapatellar fat pad mesenchymal stem cells show immunomodulatory exosomal signatures
  6. 6806
    “…Mycoplasma synoviae (MS) is a major avian pathogen that causes respiratory damage, infectious synovitis, and arthritis in chickens and causes serious economic losses to the global poultry industry. …”
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    Characterization and Evaluation of a Novel Conserved Membrane Antigen P35 of Mycoplasma synoviae
  7. 6807
    “…However, the effect of baricitinib on fibroblast-like synoviocytes (FLSs), a key component of invasive synovitis, has not been still elucidated. This study investigated whether GLS/TP production could be regulated by JAK/signal transducers and activators of transcription (STAT) signaling in FLSs derived from patients with RA. …”
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    The Janus kinase inhibitor (baricitinib) suppresses the rheumatoid arthritis active marker gliostatin/thymidine phosphorylase in human fibroblast-like synoviocytes
  8. 6808
    “…Although the primary cause of type I thumb deformity is believed to be an extensor mechanism failure resulting from synovitis of the metacarpophalangeal (MCP) joint, surgical outcomes are negatively affected as a result of flexion contracture caused by the adductor pollicis (ADP). …”
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    A New Approach for the Correction of Type I Thumb Deformity Owing to Rheumatoid Arthritis
  9. 6809
    “…Osteoarthritis (OA) is a whole joint disease characterized by synovitis, cartilage destruction, and subchondral bone sclerosis and cyst. …”
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    The Application of Extracellular Vesicles Mediated miRNAs in Osteoarthritis: Current Knowledge and Perspective
  10. 6810
    “…Patients with Charcot knees are commonly characterized by profound bone loss, diffuse synovitis, and instability in the knee joint. In this article, we report the case of a 13-year-old patient with known NTRK1 gene mutation who presented with recurrent knee joint swelling episodes and instability without pain. …”
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    Arthroplasty of a Charcot Knee in a Patient With Congenital Insensitivity to Pain
  11. 6811
    “…Exercise pain (86 [100%]), synovitis (80 [93.0%]), and intra‐articular effusion (79 [91.9%]) were the most common clinical symptoms. …”
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    Risk factors of young males with physically demanding occupations having accumulated damage of anterior cruciate ligament
  12. 6812
    “…He was at that time diagnosed with synovitis and radiocarpal arthritis. The patient underwent a partial Four-Corner Arthrodesis and Synoviectomy to preserve motor function. …”
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    Rapid Spontaneous Total Fusion of Neuropathic Arthropathy of the Wrist After Limited Intercarpal Arthrodesis: A Case Report and Brief Literature Review
  13. 6813
    “…A Gadolinium enhanced magnetic resonance imaging showed no evidence of synovitis, but BME was observed in the talus and transient regional osteoporosis was diagnosed. …”
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    Transient regional osteoporosis of the ankle with shifting bone marrow edema pattern within the joint()
  14. 6814
    “…Osteoarthritis (OA) is an age-related chronic degenerative joint disease where the main characteristics include progressive degeneration of cartilage, varying degrees of synovitis, and periarticular osteogenesis. However, the underlying factors involved in OA pathogenesis remain elusive which has resulted in poor clinical treatment effect. …”
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    HK2: a potential regulator of osteoarthritis via glycolytic and non-glycolytic pathways
  15. 6815
    “…Out of 164 OCD lesions, 10 did not heal (6.09%); (4) Conclusions: Surgical treatment of stable and unstable OCD in children with the use of bioabsorbable implants facilitates a high rate of healing and a good clinical outcome; treatment of juvenile OCD is associated with a better outcome compared to adult OCD; the use of bioabsorbable implants for the treatment of humeral capitellum OCD is associated with a more frequent incidence of synovitis (18.2%).…”
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    Evaluation of Osteochondritis Dissecans Treatment with Bioabsorbable Implants in Children and Adolescents
  16. 6816
    por Wang, Mingchuan, Chen, Cai
    Publicado 2022
    “…Inspired by Galerkin–FFT methods, a well-defined mask projector is used for stress and mixed control, and the derived nonlinear equations are solved in Newton iterations with Krylov solvers, simplifying implementation. One application example of the single-point calculator in developing sophisticated models for anisotropic single crystal rate-independent elastoplasticity is given, illustrating that the proposed algorithm can simulate asymmetrical deformation responses under uni-axial loading. …”
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    On the Single-Point Calculation of Stress–Strain Data under Large Deformations with Stress and Mixed Control
  17. 6817
    “…Midstance changes suggest that the knee’s joint degenerative changes, such as synovitis, can be linked to hip OA secondary changes. …”
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    Osteoarthritis induces gender-related changes in the knee range of motion
  18. 6818
    “…Mice with RGS12 deficiency or treatment of RGS12 shRNA nanoparticles significantly decreased the clinical score, paw swelling, synovitis, and cartilage destruction during inflammatory arthritis by inhibiting the activation of synovial fibroblasts. …”
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    Regulator of G protein signaling 12 drives inflammatory arthritis by activating synovial fibroblasts through MYCBP2/KIF2A signaling
  19. 6819
    “…These factors may contribute to the observed increased rates of persistent synovitis, premature end-stage joint damage and mortality. …”
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    Disparities in rheumatoid arthritis outcomes for North American Indigenous populations
  20. 6820
    “…Massive intra-articular infiltration of proinflammatory macrophages is a prominent feature of rheumatoid arthritis (RA) lesions, which are thought to underlie articular immune dysfunction, severe synovitis and ultimately joint erosion. Here we report an efferocytosis-informed nanoimitator (EINI) for in situ targeted reprogramming of synovial inflammatory macrophages (SIMs) that thwarts their autoimmune attack and reestablishes articular immune homeostasis, which mitigates RA. …”
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    Remodeling articular immune homeostasis with an efferocytosis-informed nanoimitator mitigates rheumatoid arthritis in mice
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