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  1. 7221
    “…Fibroblast-like synoviocytes (FLSs) are the major effector cells that lead to rheumatoid arthritis (RA) synovitis and joint destruction. Our previous studies showed that Sonic Hedgehog (SHH) signaling pathway is involved in aberrant activation of RA-FLSs and inhibition of SHH pathway decreases proliferation and migration of RA-FLSs. …”
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    Sonic Hedgehog Signaling Pathway Mediates Proliferation and Migration of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis via MAPK/ERK Signaling Pathway
  2. 7222
    “…Additionally, according to histologic evaluation, reduced synovitis and articular destruction were observed in MSC-treated groups. …”
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    Comparison of therapeutic effects of different mesenchymal stem cells on rheumatoid arthritis in mice
  3. 7223
    “…OBJECTIVE: National guidelines advocate referring patients with persistent synovitis to rheumatology within 3 working days of presentation to primary care. …”
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    Primary care challenges in diagnosing and referring patients with suspected rheumatoid arthritis: a national cross-sectional GP survey
  4. 7224
    “…METHODS: Retrospective single-centre comparative study of pediatric and adult patients diagnosed with chronic recurrent multifocal osteomyelitis (CRMO)/CNO or synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome treated at the Medical University of Graz. …”
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    Chronic non-bacterial osteomyelitis: a comparative study between children and adults
  5. 7225
    “…PURPOSE: Synovitis is common in knee osteoarthritis and is associated with both knee pain and progression of disease. …”
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    Measurement of synovial tissue volume in knee osteoarthritis using a semiautomated MRI‐based quantitative approach
  6. 7226
    “…Senescence of cultured SF is accelerated upon exposure to TNFα or oxidative stress and may contribute to the pathogenesis of synovitis by increasing the production of pro-inflammatory mediators.…”
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    Senescent synovial fibroblasts accumulate prematurely in rheumatoid arthritis tissues and display an enhanced inflammatory phenotype
  7. 7227
    “…On Day 35, joints were evaluated by microscopic histopathology for cartilage degeneration, collagen degeneration, synovitis, and cytokine expression (tumor necrosis factor α, transforming growth factor β). …”
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    Viscosupplementation may preserve tibial cartilage and collagen in osteoarthritis: findings from a preclinical model of osteoarthritis
  8. 7228
    “…PURPOSE: Rheumatoid arthritis (RA) is a systemic inflammatory disease characterized by chronic destructive synovitis and possible multisystem involvement. This study aimed to survey the treatment satisfaction of physicians and patients with RA, and to explore the potential factors. …”
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    Satisfaction of Patients and Physicians with Treatments for Rheumatoid Arthritis: A Population-Based Survey in China
  9. 7229
    “…Invasiveness of FLSs in vivo was evaluated using a humanized synovitis animal model. We observed that treatment of SHH agonist (SAG) significantly increased the levels of phosphorylation of JNK and c-Jun, while SHH antagonist (cyclopamine) significantly decreased the expression of phospho-JNK and phospho-c-Jun in FLSs. …”
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    Sonic Hedgehog Regulates Proliferation, Migration and Invasion of Synoviocytes in Rheumatoid Arthritis via JNK Signaling
  10. 7230
    por Gong, Liang, Wang, Lun, Cao, Yihan, Li, Chen
    Publicado 2020
    “…RATIONALE: Synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome is a rare disease without standard treatments. …”
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    Rapid induction of clinical remission in SAPHO syndrome using high-dose Tripterygium glycosides: A case report
  11. 7231
    “…CONCLUSION: The image scores of MSCT are generally consistent with MRI except for mild synovitis, which can be used as an alternative for the evaluation of HA.…”
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    Multislice spiral computed tomography imaging in evaluating hemophilic arthropathy
  12. 7232
    “…BACKGROUND: Mandible osteomyelitis can occur in synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome, a rare chronic inflammatory disease; however, few studies have explored its characteristics and management. …”
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    Mandibular involvement in SAPHO syndrome: a retrospective study
  13. 7233
    “…Assessment of combined pathologies revealed that partial rotator cuff tear of less than 25% thickness, was most common (overall 83.3%; with bursal 57% and articular 23%). Subacromial synovitis and adhesion were also frequent (53.3%). …”
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    Clinical Outcome after Arthroscopic Capsular Release for Adhesive Capsulitis of the Shoulder
  14. 7234
    “…INTRODUCTION: The aim of the study was to evaluate the impact of disease activity, selected serum cytokines, and therapy on metabolic syndrome (MetS) components in patients with synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome. …”
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    Serum interleukin-23 protects, whereas methotrexate treatment stimulates selected components of the metabolic syndrome in patients with SAPHO syndrome
  15. 7235
    “…BACKGROUND: Rheumatoid arthritis (RA) is characterized by systemic synovitis with bone erosion and joint cartilage degradation. …”
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    Usefulness of Cytokine Gene Polymorphisms for the Therapeutic Choice in Japanese Patients with Rheumatoid Arthritis
  16. 7236
    “…RESULTS: Global deletion of 11β-HSD1 resulted in a profound GC resistance in animals receiving corticosterone, characterised by persistent synovitis, joint destruction and inflammatory leucocyte infiltration. …”
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    Local steroid activation is a critical mediator of the anti-inflammatory actions of therapeutic glucocorticoids
  17. 7237
    “…Abnormal expression of long non-coding RNAs (lncRNAs) affects the metabolism, synovitis, autophagy and apoptosis of chondrocytes, as well as the production of cartilage matrix. …”
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    Expression profiles of long non-coding RNAs in the cartilage of patients with knee osteoarthritis and normal individuals
  18. 7238
    “…Depending on the compressed structure, it is categorized into neurological, arterial and venous TOS. SAPHO syndrome (synovitis–acne–pustulosis–hyperostosis–osteitis syndrome) is a rare chronic inflammatory disease of unknown etiology. …”
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    Thoracic outlet syndrome in a patient with SAPHO syndrome – A case report
  19. 7239
    “…Here, IL-23 transcriptomic/protein expression was strongly linked to patients with high-grade synovitis who, however, were not distinguishable by conventional clinimetric measures. …”
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    IL-23 skin and joint profiling in psoriatic arthritis: novel perspectives in understanding clinical responses to IL-23 inhibitors
  20. 7240
    “…The posterior talofibular ligament was intact in both groups. Synovitis and scar tissue were more common in group A (p = 0.01) compared to group B. …”
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    Chronic Lateral Ankle Instability in Highly Active Patients: A Treatment Algorithm Based on the Arthroscopic Assessment of the Calcaneofibular Ligament
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