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7621por Han, Chenchen, Li, Yifan, Zhang, Yuwen, Wang, Yang, Cui, Dongqian, Luo, Tingting, Zhang, Yu, Liu, Qian, Li, Hao, Wang, Chun, Xu, Dexiang, Ma, Yang, Wei, Wei“…CP-25 could down-regulate GRK2 expression, up-regulate EP4 expression, and improve synovitis of CIA rats. CP-25 and GRK2 inhibitors (paroxetine or GSK180736A) inhibited the abnormal proliferation of FLS in RA patients and CIA rats by down-regulating GRK2 translocation to EP4 receptor. …”
Publicado 2021
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7622“…BACKGROUND: Rheumatoid arthritis (RA) is a chronic systemic autoimmune disorder characterized by inflammatory cell infiltration, leading to persistent synovitis and joint destruction. The pathogenesis of RA remains unclear. …”
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7623por Palmowski, Yannick, Jung, Tobias, Doering, Anne-Katrin, Gwinner, Clemens, Schatka, Imke, Bartek, Benjamin“…The most frequently observed abnormalities were synovitis/effusion (49/50, 98%), bone marrow oedema (44/50, 88%) and cartilage damage (42/50, 84%). …”
Publicado 2021
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7624por Selley, Ryan, Lawton, Cort, Dooley, Matthew, Swensen, Stephanie, Marom, Niv, Kelly, Bryan, Ranawat, Anil, Nawabi, Danyal“…In cases in which instability was present, 39.4% were secondary to traumatic capsular deficiency, 34.2% were attributed to atraumatic capsular deficiency and 26.3% were attributed to borderline dysplasia, Numerous other findings were noted at the time of revision arthroscopy, 100% of patients were noted to have synovitis, in 97.8% loose osteochondral fragments were noted, 90.8% had labral tears, 47.6% had adhesions and 24.5% had heterotopic ossification (Table 2). …”
Publicado 2021
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7625por Maurice, Emeline, Godineau, Thibault, Pichard, Diane, El Hafci, Hanane, Autret, Gwennhael, Bensidhoum, Morad, Migonney, Véronique, Manassero, Mathieu, Viateau, Véronique“…Healing of the transected ACL was not observed in the animals in which no graft reconstruction was performed. rp-ACLR was associated with a reduced degeneration of the ACL remnants (p = 0.004) and cartilages (p = 0.0437). Joint effusion and synovitis were significantly lower in the reconstructed group compared to the transected ACL group (p = 0.004). …”
Publicado 2022
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7626por Gianakos, Arianna L., Ivander, Axel, DiGiovanni, Christopher W., Kennedy, John G.“…The most common concomitant pathology found during arthroscopic evaluation included synovitis, osteophytes, meniscoid lesions, and AITFL injury. …”
Publicado 2022
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7627“…RESULTS: Three m6A-related genes (FAM71F1, MT1E, and MYEOV) were identified as prognostic genes for LUSC. …”
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7628“…The safety cohort showed no significant differences except for an increase in synovitis at day 21, which could be evidence of a xenogeneic response in this model. …”
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7629por Courties, Alice, Deprouw, Camille, Rousseau, Alexandra, Berard, Laurence, Touati, Amel, Kalsch, Johanna, Villevieille, Margaux, Maheu, Emmanuel, Miquel, Anne, Simon, Tabassome, Berenbaum, Francis, Sellam, Jeremie“…Patients with symptomatic EHOA (score ≥40/100 mm on a visual analogue scale (VAS) for pain of 0–100 mm) and inflammatory EHOA (≥1 clinical and ultrasonography-determined interphalangeal synovitis) are included in 18 hospital centres (17 rheumatology and 1 rehabilitation departments) in France. …”
Publicado 2022
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7630por Yang, Mingyi, Zheng, Haishi, Su, Yani, Xu, Ke, Yuan, Qiling, Aihaiti, Yirixiati, Cai, Yongsong, Xu, Peng“…OBJECTIVE: Rheumatoid arthritis (RA) is a nonspecific, chronic, systemic autoimmune disease characterized by symmetric polyarticular synovitis. Bioinformatics analysis of potential biomarkers, mRNA–miRNA–lncRNA axes, and signaling pathways in the pathogenesis of RA provides potential targets and theoretical basis for further research on RA. …”
Publicado 2022
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7631por Carbonell-Bobadilla, Natalia, Soto-Fajardo, Carina, Amezcua-Guerra, Luis M., Batres-Marroquín, Ana Beatriz, Vargas, Tania, Hernández-Diazcouder, Adrian, Jiménez-Rojas, Valentin, Medina-García, Ana Cristina, Pineda, Carlos, Silveira, Luis H.“…We found greater severity of PD signals in the 2nd MCP and 3rd MCP joints of the seropositive patients, while synovitis severity was higher only in the 2nd MCP joints. …”
Publicado 2022
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7632“…BACKGROUND: The difficulty in determining synovitis, tenosynovitis, or enthesitis by physical examination (PE) has limited the diagnostic capability of CASPAR for psoriatic arthritis (PsA). …”
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7633por Gordon, David, Kivitz, Alan, Singhal, Atul, Burt, David, Bangs, Madison C., Huff, Emma E., Hope, Heidi Rath, Monahan, Joseph B.“…The secondary objectives were to assess the median percentage change from baseline high‐sensitivity C‐reactive protein (hs‐CRP) levels, the mean change from baseline in Disease Activity Score in 28 joints based on CRP level (DAS28‐CRP) and Rheumatoid Arthritis Magnetic Resonance Imaging Score hand‐wrist assessments of synovitis or bone erosion at week 12, and the proportion of patients with American College of Rheumatology 20/50/70 (ACR 20/50/70) and with DAS28‐CRP scores of less than 2.6. …”
Publicado 2023
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7634por Buta, Martin, Annand, Domenic, Findeisen, Sarah, Hickey, Sean, Sheridan, Robert, Friedstat, Jonathan, Schulz, John, Bojovic, Branko, Goverman, JeremyEnlace del recurso
Publicado 2023
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7635por Korać, Miloš, Rupnik, Maja, Nikolić, Nataša, Jovanović, Milica, Tošić, Tanja, Malinić, Jovan, Mitrović, Nikola, Marković, Marko, Vujović, Ankica, Peruničić, Sanja, Bojović, Ksenija, Djordjević, Vladimir, Barać, Aleksandra, Milošević, IvanaEnlace del recurso
Publicado 2020
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7639“…He had solid skin-coloured papular lesions and dermal nodules overlying erythematous thickened oedematous skin. Synovitis was noted in his MCPs and wrists. There was no nailfold capillary change or symptoms of Raynaud’s. …”
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7640por Watkins, Clara, Nagra, Deepak, Alveyn, Edward, Adas, Maryam, Baldwin, Chris, Galloway, James“…On assessment, his skin lesions had returned with dactylitis in his toes and synovitis in his wrists. Investigations revealed no improvement in his vital capacity and a markedly raised Il2Ra of 5739ng/L which was previously 2812ng/L (reference range 423-1843ng/L). …”
Publicado 2023
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