“…The auto inflammatory bone disorder includes chronic non-bacterial osteomyelitis (CNO) and its severe form chronic recurrent multifocal osteomyelitis (CRMO); synovitis, acne, pustulosis, hyperostosis, osteitis (SAPHO) syndrome; Majeed syndrome; deficiency of interleukin-1 receptor antagonist (DIRA) and cherubism. …”
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“…Functional outcome surveys include the Kerlan-Jobe Orthopaedic Clinic (KJOC) score, Conway-Jobe score, Andrews-Timmerman (AT) elbow score, and the Single Assessment Numeric Evaluation (SANE) score. …”
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“…Pearson correlation coefficients of 0.65, 0.62, and 0.31 were calculated between the YTS and the Pediatric Outcomes Data Collection Instrument Sports/Physical Functioning Scale (PODCI), Kerlan Jobe Orthopaedic Clinic Shoulder and Elbow Score (KJOC), and the Quick Disabilities of the Arm, Shoulder and Hand Score (QuickDASH). …”
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“…Four hundred thirty-five Ukrainian pharmacy students participated in the quantitative analysis (a survey) that took place on April–May, 2019 at Bogomolets National Medical University (Kyiv, Ukraine). They were surveyed about legalization of medical cannabis in Ukraine, advisability of including cannabis and cannabinoids related data into educational programs, and other issues. …”
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“…A fellowship-trained musculoskeletal radiologist reviewed preoperative MRIs and calculated Whole Organ Magnetic Resonance Imaging Scores (WORMS) for meniscus, cartilage, bone marrow edema pattern (BMEP) in 6 knee locations as well as effusion/synovitis and meniscal extrusion. Radiographs were scored with Kellgren-Lawrence (KL) scores to assess presence and severity of osteoarthritis. …”
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“…In this report, we describe a case of ANCA associated vasculitis (AAV) with 3rd nerve palsy, finger joint synovitis, fevers and cough, preceded by zoledronate infusion. …”
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“…This patient's constellation of signs and symptoms could be fully compatible with both SLE and secondary syphilis; however, only weakly positive ANA levels with negative dsDNA, normal complements levels make the diagnosis of SLE questionable; our patient did not fulfil the SLE (SLICC) or the EULAR/ACR classification criteria as only the presence of synovitis, weakly positive ANA levels and weakly positive cardiolipin antibodies (medium or high titres are required for diagnosis) were present. …”
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“…DISCUSSION: SAPHO syndrome is a rare disorder, which consists of synovitis, acne, pustulosis, hyperostosis and osteitis. …”
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“…Holland, MD, Aridis: Advisor/Consultant|Basilea Pharmaceutica: Advisor/Consultant|Karius: Advisor/Consultant|Lysovant: Advisor/Consultant Vance G. Fowler, MD, MHS, Amphliphi Biosciences, Integrated Biotherapeutics; C3J, Armata, Valanbio; Akagera, Aridis, Roche, Astra Zeneca: Advisor/Consultant|Genentech, Regeneron, Deep Blue, Basilea, Janssen;: Grant/Research Support|Infectious Diseases Society of America: Honoraria|MedImmune, Allergan, Pfizer, Advanced Liquid Logics, Theravance, Novartis, Merck; Medical Biosurfaces; Locus; Affinergy; Contrafect; Karius;: Grant/Research Support|Novartis, Debiopharm, Genentech, Achaogen, Affinium, Medicines Co., MedImmune, Bayer, Basilea, Affinergy, Janssen, Contrafect, Regeneron, Destiny,: Advisor/Consultant|Sepsis diagnostic: Patent pending|UpToDate: Royalties|Valanbio and ArcBio: Stock Options Mark E. …”
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“…There was no rash, clinical synovitis, or organomegaly.  Investigations included: Throat cultures: negative; Urine dip: trace blood; Anti-Streptolysin O Titres (ASOT): 1600 units/ml; Anti-DNAse B titres: 800; WCC: 16, neutrophils: 73%; ESR: 62; CRP: 120; Ferritin: 1322 (5x upper limit of normal); Transaminitis: ALT: 234, AST: 123; LDH: 428; CK: 47; ANCA, ANA, rheumatoid factor, anti-CCP, CMV, EBV, hepatitis A, B & C, HIV: negative; Echocardiogram: normal; CT head, chest, abdomen, pelvis: normal Our patient was referred to rheumatology and treatment for presumed AOSD was commenced with 30mg prednisolone (weaning dose) and methotrexate. …”
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“…She was tender on palpation of her knees, elbows and ankles with no overt synovitis detected. She had no palpable peripheral lymphadenopathy. …”
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“…On rheumatologic assessment there was an asymmetric inflammatory arthropathy, with small joint synovitis as well as large volume joint effusions of elbows and knees. …”
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“…He then experienced multiple joint pains with synovitis. His father had been diagnosed from a young age with sarcoidosis. …”
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“…Six months later she re-presented with abdominal pain, synovitis and had nephrotic range proteinuria. She was treated again for LEn after gastroenterology input. …”
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“…Holland, MD, Aridis: Advisor/Consultant|Lysovant: Advisor/Consultant Henry Chambers, MD, Merck: DSMB member|Merck: Stocks/Bonds|Moderna: Stocks/Bonds Vance G. …”
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“…Examination also revealed clinical evidence of a moderate sized right sided pleural effusion and inflammatory synovitis in bilateral knees. He appeared acutely confused and was disorientated for the first three days of admission. …”
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“…On further discussion when I reviewed her she described stiffness and pain in axial skeleton in keeping with PMR. There was no synovitis or tenderness in the joints, no rash, no sinusitis and no muscle tenderness. …”
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“…In this patient, the presence of synovitis, high fevers, raised inflammatory markers and serum ferritin fit with adult-onset Still’s disease (AOSD). …”
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“…Examination did not demonstrate synovitis or rashes. Her cardiovascular and abdominal examination was normal. …”
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“…Ultrasound demonstrated sub-clinical synovitis. Her medication was optimised but the ankle swelling persisted, rendering her wheelchair-reliant. …”
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