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  1. 14461
    “…Identification of drug–target interactions through biological experiments is time consuming, laborious, and costly. Therefore, using computational approaches to predict candidate targets is a good way to reduce the cost of wet-lab experiments. …”
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    Gradient Boosting Decision Tree-Based Method for Predicting Interactions Between Target Genes and Drugs
  2. 14462
    “…Bimaxillary osteotomies were the most prevalent (55%), followed by LeFort I (32%), and 26% had genioplasty. Conclusion: IOFTN is a reliable tool to identify patients in need of orthognathic surgery. …”
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    Orthognathic Surgery Treatment Need in a Turkish Adult Population: A Retrospective Study
  3. 14463
    “…However, conventional methods for measuring aqueous iron pools remain laborious and costly and often require sophisticated equipment and/or additional processing steps to remove the iron ions from the original environmental source. …”
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    Iron detection and remediation with a functionalized porous polymer applied to environmental water samples
  4. 14464
    “…Visual examination of the crop is laborious and time consuming. Therefore, quick and precise estimation of heading date of paddy rice is highly essential. …”
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    Automatic estimation of heading date of paddy rice using deep learning
  5. 14465
    “…However, the identification of anti-tubercular peptides (AtbPs) via experimentation is laborious and expensive; hence, the development of an efficient computational method is necessary for the prediction of AtbPs prior to both in vitro and in vivo experiments. …”
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    AtbPpred: A Robust Sequence-Based Prediction of Anti-Tubercular Peptides Using Extremely Randomized Trees
  6. 14466
    “…However, less attention is given to determining whether these names represent valid biological entities because this is perceived as both a laborious chore and an undesirable research outcome. …”
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    Genome-wide SNP Data Reveal an Overestimation of Species Diversity in a Group of Hawkmoths
  7. 14467
    “…The promise of the term psychosomatic lies in its efforts to rework standard, bifurcated models of mind and body: somatic acts are simultaneously psychic acts. …”
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    Corrective biology: psychosomatics in and as neuropsychoanalysis
  8. 14468
    “…Current methods for detecting D. nodosus are difficult, laborious and time-consuming. Recently, we developed a robust LAMP assay (VDN LAMP) that was able to identify aprV2 positive D. nodosus in-field. …”
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    Evaluation of loop-mediated isothermal amplification (LAMP) assay for detection of aprV2 positive Dichelobacter nodosus in-field by secondary users
  9. 14469
    “…However, these approaches are expensive and laborious involving complex procedures for successful editing. …”
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    Modern Trends in Plant Genome Editing: An Inclusive Review of the CRISPR/Cas9 Toolbox
  10. 14470
    “…Experimental methods for 6mA detection in eukaryotes genome are laborious and expensive. Therefore, it is necessary to develop computational methods to identify 6mA sites on a genomic scale, especially for plant genomes. …”
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    iDNA6mA-Rice: A Computational Tool for Detecting N6-Methyladenine Sites in Rice
  11. 14471
    “…However, phenotypic analysis of these strains can be laborious, particularly for quantitative traits requiring multiple measurements per strain. …”
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    Population Selection and Sequencing of Caenorhabditis elegans Wild Isolates Identifies a Region on Chromosome III Affecting Starvation Resistance
  12. 14472
    “…Improved understanding of these traits relies on determining mosquito karyotype, which currently depends upon laborious cytogenetic methods whose application is limited both by the requirement for specialized expertise and for properly preserved adult females at specific gonotrophic stages. …”
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    In Silico Karyotyping of Chromosomally Polymorphic Malaria Mosquitoes in the Anopheles gambiae Complex
  13. 14473
    “…The current screening methods use a radio-binding assay (RBA) for single IAb measurement, which are laborious and inefficient for large-scale screening. …”
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    High-throughput multiplexed autoantibody detection to screen type 1 diabetes and multiple autoimmune diseases simultaneously
  14. 14474
    “…Sputum induction is currently the only available method for assessing airway neutrophilia but is laborious and time-consuming. This analysis examined the correlation between systemic and airway inflammatory responses to endotoxin to determine if peripheral blood could serve as a surrogate marker for neutrophilic airway inflammation. …”
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    Systemic inflammatory response to inhaled endotoxin does not correlate with airway response
  15. 14475
    “…However, approaches to identify novel vaccine candidates are commonly laborious and protracted. While surface proteins are suitable vaccine candidates and can elicit antibacterial antibody responses, systematic approaches to define surfomes from gram-negatives have rarely been successful. …”
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    A mass spectrometry guided approach for the identification of novel vaccine candidates in gram-negative pathogens
  16. 14476
    “…Current reverse genetics (RG) strategy to rescue BTV mainly rely on in vitro synthesis of RNA transcripts from cloned complimentary DNA (cDNA) corresponding to viral genome segments with the aid of helper plasmids. RNA synthesis is a laborious job which is further complicated with a need for expensive reagents and a meticulous operational procedure. …”
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    PCR-based reverse genetics strategy for bluetongue virus recovery
  17. 14477
    “…Empirically quantifying tidally-influenced river discharge is typically laborious, expensive, and subject to more uncertainty than estimation of upstream river discharge. …”
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    An expanded rating curve model to estimate river discharge during tidal influences across the progressive-mixed-standing wave systems
  18. 14478
    “…It is not necessarily more difficult to measure antimicrobial activity the traditional way, but it is, however, more laborious. In the present study, we developed a new method to measure the antimicrobial activity of LA in multiple samples with a microplate reader. …”
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    Measuring the Antimicrobial Activity of Lauric Acid against Various Bacteria in Human Gut Microbiota Using a New Method
  19. 14479
    por Day, Kevin A., Bastian, Amy J.
    Publicado 2019
    “…However, when learning a complex movement pattern, serial training is not only laborious but can also be ineffective. Often, movement features are linked such that they cannot simply be added together as we progress through training. …”
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    Providing low-dimensional feedback of a high-dimensional movement allows for improved performance of a skilled walking task
  20. 14480
    “…CONCLUSION: This novel technique employing TMC nanoparticulate system could be potentially used as a source to raise sera against chitosan in an inexpensive and less laborious manner. Rapid detection of fungal contamination by the polyclonal antibodies could help in devising a quick solution. …”
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    In-vitro Detection of Phytopathogenic Fungal Cell Wall by Polyclonal Sera Raised Against Trimethyl Chitosan Nanoparticles
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