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14501“…Whereas most edible yams are tropical species, Chinese yam could be cultivated widely in Europe and other temperate regions to take advantage of its nutritional and bioactive properties. However, this is a laborious process and agronomic knowledge is fragmented. …”
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14502“…The traditional plate culturing methods for identifying antibiotic-resistant bacteria is laborious and time-consuming. Bulk PCR (Polymerase Chain Reaction) and qPCR are limited by poor detection sensitivity, which is critical for the early-stage detection of bloodstream infections. …”
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14503“…This study aimed to explore modifications of three existing methods to analyse nociceptive behaviours using two TMD mouse models: (1) mechanical allodynia was tested using von Frey filaments in the mouse TMJ region by placing mice in specially designed chambers; (2) bite force was measured using the Economical Load and Force (ELF) system; and (3) spontaneous feeding behaviour tests, including eating duration and frequency, were analysed using the Laboratory Animal Behaviour Observation Registration and Analysis System (LABORAS). We successfully assessed changes in nociceptive behaviours in two TMD mouse models, a unilateral anterior crossbite (UAC)-induced TMD mouse model and a β-catenin conditional activation mouse model. …”
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14504por Zhang, Man, Ye, Lili, Huang, Hao, Cheng, Dandan, Liu, Kaixin, Wu, Wenbo, Shen, Fukui, Jiang, Zhihong, Hou, Yuanyuan, Bai, Gang“…However, developing the formulation of each drug is a time-consuming and laborious task. RESULTS: In this study, a universal lung-targeting nanoparticle was designed and constructed. …”
Publicado 2020
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14505por Millstead, Luke, Jayakody, Hiranya, Patel, Harsh, Kaura, Vihaan, Petrie, Paul R., Tomasetig, Florence, Whitty, Mark“…Despite the key role played by these cells, their microscopic analysis is largely manual, requiring intricate sample collection, laborious microscope application and the manual operation of a graphical user interface to identify and measure stomata. …”
Publicado 2020
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14506por Thiele, Sarah, Isselmann, Ben, Pfau, Maximilian, Holz, Frank G., Schmitz-Valckenberg, Steffen, Wu, Zhichao, Guymer, Robyn H., Luu, Chi D.“…Because manual quantification of rEZR is laborious and lacks of spatial resolution, automated quantification of the rEZR would be beneficial. …”
Publicado 2020
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14507“…The prediction of hydroxylysine sites by experimental methods is difficult, laborious and highly expensive. In silico technique is an alternative approach to identify hydroxylysine sites in proteins. …”
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14508“…However, the effect of DOM sources on the microbial reworking and degradation of the DOM pool remains debated. …”
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14509por Papadimitropoulou, Katerina, Stijnen, Theo, Riley, Richard D., Dekkers, Olaf M., le Cessie, Saskia“…However, gaining access to IPD can be a laborious task (if possible at all) and in practice only summary (aggregate) data are commonly available. …”
Publicado 2020
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14510por Chen, Fang, Zhuo, Chunliu, Xiao, Xirong, Pendergast, Thomas H., Devos, Katrien M.“…However, the original thioacidolysis procedure is complex, laborious, and time consuming, making it difficult to be adopted for large-scale screening in biomass research. …”
Publicado 2021
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14511“…The techniques commonly used, microscopic counting and quantitative PCR (qPCR) are laborious and time-consuming. In aquatic and marine ecosystems, phycocyanin (PC), a photosynthesis pigment produced by cyanobacteria, is commonly used to monitor cyanobacteria biomass. …”
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14512“…Although multilevel sectioning and the use of immunohistochemistry (IHC) have improved the detection of micrometastases in LNs, this approach is laborious, time‐consuming, and costly. A novel molecular technique for the detection of LN metastases of tumors, called one‐step nucleic acid amplification (OSNA), is a rapid and semi‐quantitative examination quantifying the number of cytokeratin 19 (CK‐19) mRNA copies derived from a tumor. …”
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14513“…Unfortunately, the discovery of repellents is slow, laborious, and error‐prone. To this end, we have taken a giant stride toward improving the speed and accuracy of repellant discovery by constructing a prototypical whole‐cell biosensor for accurate detection of mosquito behavior‐modifying compounds such as repellants. …”
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14514por Šiaulys, Andrius, Vaičiukynas, Evaldas, Medelytė, Saulė, Olenin, Sergej, Šaškov, Aleksej, Buškus, Kazimieras, Verikas, Antanas“…However, due to the laborious and time-consuming manual analysis procedure, only a small part of the information stored in the archives of underwater images is retrieved. …”
Publicado 2021
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14515por Bondarenko, Pavel, Nichols, Andrew C., Xiao, Gang, Shi, Rachel Liuqing, Chan, Pik Kay, Dillon, Thomas M, Garces, Fernando, Semin, David J., Ricci, Margaret S.“…Currently, criticality of modifications is assessed by a laborious process of collecting antibody fractions from the soft chromatography techniques ion exchange and hydrophobic interaction chromatography and characterizing the fractions one-by-one for potency and chemical modifications. …”
Publicado 2021
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14516“…Various detection and identification strategies exist; however, they are laborious and time consuming and hence the detection takes longer time. …”
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14517por Zhang, Zehui, Wang, Xiaoqin, Wei, Xiaojun, Zheng, Sophia W., Lenhart, Brian J., Xu, Peisheng, Li, Jie, Pan, Jing, Albrecht, Helmut, Liu, Chang“…However, commercially available enzyme-linked immunosorbent assays (ELISA) are laborious and non-quantitative, while point-of-care assays suffer from low detection accuracy. …”
Publicado 2021
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14518por Sung, Tzu‐Cheng, Jiang, Yi‐Peng, Hsu, Jhe‐Yu, Ling, Qing‐Dong, Chen, Hao, Kumar, Suresh S., Chang, Yung, Hsu, Shih‐Tien, Ye, Qingsong, Higuchi, Akon“…However, these hypoimmunogenic or universal hPSCs prepared previously were all genetically edited, which makes laborious processes to check and evaluate no abnormal gene editing of hPSCs. …”
Publicado 2021
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14519por Castel, Pau, Holtz-Morris, Ann, Kwon, Yongwon, Suter, Bernhard P., McCormick, Frank“…Most PPIs occur through small domains or motifs, which are challenging and laborious to map by using standard biochemical approaches because they generally require the cloning of several truncation mutants. …”
Publicado 2020
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14520por Imboden, Sara, Liu, Xuanqing, Lee, Brandon S., Payne, Marie C., Hsieh, Cho-Jui, Lin, Neil Y. C.“…Performing such measurements non-invasively and at scale has remained challenging as conventional methods such as flow cytometry and immunofluorescence microscopy typically require cell fixation and laborious sample preparation. Here, we developed an artificial intelligence (AI)-based method that converts transmitted light microscopy images of MSCs into quantitative measurements of protein expression levels. …”
Publicado 2021
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