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  1. 14621
    “…Examining the entire muscle using consecutive cross‐sections is extremely laborious, we provide consideration to reduce the dataset without loosing spatial information. …”
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    Discovering fiber type architecture over the entire muscle using data‐driven analysis
  2. 14622
    “…In this study, we highlight the phoretic relationship between D. corticola and the oak pinhole borer Platypus cylindrus (Coleoptera, Curculionidae) which massively colonizes debarked cork oaks in southern Europe. We extracted DNA from 154 adults of P. cylindrus collected in six cork oak stands in north‐eastern Spain during the summer of 2021. …”
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    New qPCR protocol to detect Diplodia corticola shows phoretic association with the oak pinhole borer Platypus cylindrus
  3. 14623
    “…However, diagnosing ASD with fMRI and sMRI for specialists is often laborious and time-consuming; therefore, several computer-aided design systems (CADS) based on artificial intelligence (AI) have been developed to assist specialist physicians. …”
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    Automatic autism spectrum disorder detection using artificial intelligence methods with MRI neuroimaging: A review
  4. 14624
    “…Traditional culture-dependent methods are lengthy, expensive, laborious, and unable to detect VBNC. Hence, there is a need to develop a rapid, simple, and cost-effective detection method to differentiate between viable/dead E. coli O157:H7 and detect VBNC cells. …”
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    Point-of-Care Lateral Flow Detection of Viable Escherichia coli O157:H7 Using an Improved Propidium Monoazide-Recombinase Polymerase Amplification Method
  5. 14625
    “…However, the development of monoclonal antibodies is often long, laborious, and unprofitable. Here, we report the development of chicken polyclonal neutralizing antibodies against SARS-CoV-2 infection. …”
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    Antiviral Immunoglobulins of Chicken Egg Yolk for Potential Prevention of SARS-CoV-2 Infection
  6. 14626
    “…Computable models as a fundamental candidate for traditional biological experiments have been applied in inferring lncRNA–disease association (LDA) for many years, without time-consuming and laborious limitations. However, sparsity inherently existing in known heterogeneous bio-data is an obstacle to computable models to improve prediction accuracy further. …”
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    Identifying lncRNA–disease association based on GAT multiple-operator aggregation and inductive matrix completion
  7. 14627
    “…Experimental methods for affinity maturation are expensive, laborious, and time-consuming and rarely allow the efficient exploration of the relevant design space. …”
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    Hallucinating structure-conditioned antibody libraries for target-specific binders
  8. 14628
    “…Nevertheless, analysis of historical maps based on supervised learning can be limited by the laborious manual map annotations. In this work, we propose a semi-supervised learning method that can transfer the annotation of maps across years and allow map comparison and anthropogenic studies across time. …”
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    Semi-supervised learning for topographic map analysis over time: a study of bridge segmentation
  9. 14629
    por Pang, Yihe, Liu, Bin
    Publicado 2022
    “…Experimental identification of the molecular functions of IDP in the wet lab is an expensive and laborious procedure that is not applicable on a large scale. …”
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    DMFpred: Predicting protein disorder molecular functions based on protein cubic language model
  10. 14630
    “…This study demonstrates that CRM combined with chemometrics can serve as a rapid, reliable, and efficient method for the detection and identification of foodborne pathogenic bacteria without any laborious pre-treatments. Six important foodborne pathogenic bacteria including S. flexneri, L. monocytogenes, V. cholerae, S. aureus, S. typhimurium, and C. botulinum were investigated with CRM. …”
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    Identification of foodborne pathogenic bacteria using confocal Raman microspectroscopy and chemometrics
  11. 14631
    “…The final curated and processed data as well as raw data are currently available through https://bbd.labworks.org/ds/bbd/hshus.…”
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    High resolution dataset from a net-zero home that demonstrates zero-carbon living and transportation capacity
  12. 14632
    “…However, CRISPR methods generally rely on preassembled DNAs and extra cloning steps to deliver gRNA, Cas protein, and donor DNA. These laborious steps might hinder its usefulness. Here, we propose an alternative method, Assembly and CRISPR-targeted in vivo Editing (ACtivE), that only relies on in vivo assembly of linear DNA fragments for plasmid and donor DNA construction. …”
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    ACtivE: Assembly and CRISPR-Targeted in Vivo Editing for Yeast Genome Engineering Using Minimum Reagents and Time
  13. 14633
    “…T. parva has a large proteome, with >4000 protein-coding genes, making T-cell antigen identification using conventional screening approaches laborious and expensive. To date, only a limited number of T-cell antigens have been described. …”
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    Immunopeptidomic Analysis of BoLA-I and BoLA-DR Presented Peptides from Theileria parva Infected Cells
  14. 14634
    “…BACKGROUND: The assembly of metagenomes decomposes members of complex microbe communities and allows the characterization of these genomes without laborious cultivation or single-cell metagenomics. …”
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    Persistent memory as an effective alternative to random access memory in metagenome assembly
  15. 14635
    “…However, the available experimental methods for Kcr site identification are laborious and costly. To effectively replace existing experimental approaches, some computational methods have been developed in the last few years. …”
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    CapsNh-Kcr: Capsule network-based prediction of lysine crotonylation sites in human non-histone proteins
  16. 14636
    “…However, the current grading process requires the analysis of oil palm bunches, which is laborious and tedious or prone to error due to human subjectivity. …”
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    Electrical Impedance Spectroscopy for Moisture and Oil Content Prediction in Oil Palm (Elaeis guineensis Jacq.) Fruitlets
  17. 14637
    “…For smaller studies, the library allows sidestepping the laborious construction of single targeted mutants. …”
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    Construction of an Ordered Transposon Library for Uropathogenic Proteus mirabilis HI4320
  18. 14638
    “…A new index, namely the relative change of tabletability (CoT(r)), was proposed to quantify the tabletability change, and its advantages over the reworking potential were demonstrated. On the basis of CoT(r) values, the tabletability change classification system (TCCS) was established. …”
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    Using a Material Library to Understand the Change of Tabletability by High Shear Wet Granulation
  19. 14639
    “…Traditional drug discovery is very laborious, expensive, and time-consuming, due to the huge combinatorial complexity of the discrete molecular search space. …”
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    AlphaDrug: protein target specific de novo molecular generation
  20. 14640
    “…CONTEXT: Analysis of diagnostic information in pathology reports for the purposes of clinical or translational research and quality assessment/control often requires manual data extraction, which can be laborious, time-consuming, and subject to mistakes. …”
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    An accessible, efficient, and accurate natural language processing method for extracting diagnostic data from pathology reports
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