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  1. 14641
    “…These methods involve laborious solid phase extraction, and the respective panels of target analytes are incomplete. …”
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    Semi-automated serum steroid profiling with tandem mass spectrometry
  2. 14642
    “…Generate large datasets for MIC resistance of 2D coatings is both complex and laborious. Deep learning data augmentation methods can alleviate this issue by generating synthetic electrochemical data that resembles the training data classes. …”
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    Deep learning strategies for addressing issues with small datasets in 2D materials research: Microbial Corrosion
  3. 14643
    “…However, conventional methods for CER study are laborious and time-consuming. In the meantime, the overall profile of the secondary metabolites in the fungi treated by the CER reagent is not well characterized. …”
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    Metabolomic Strategy to Characterize the Profile of Secondary Metabolites in Aspergillus aculeatus DL1011 Regulated by Chemical Epigenetic Agents
  4. 14644
    “…Thus, the ProspectBIO software allowed the finding of a new promising lipase for biotechnological application without the need for laborious and expensive conventional bioprospecting experimental steps.…”
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    Novel CaLB-like Lipase Found Using ProspectBIO, a Software for Genome-Based Bioprospection
  5. 14645
    “…Results show that the 2014 nourishment fill sands were finer than those native to the study area beach, however, reworking quickly brought the fill sands on the nourished beach into size parity with native sediments observed on a predefined control site. …”
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    Potential long-term disturbance associated with beach nourishment - insights and observations from Pea Island National Wildlife Refuge, Outer Banks, North Carolina
  6. 14646
    “…However, pigment glands are extremely small and densely distributed, manual counting is laborious and time-consuming, and difficult to count quickly and accurately. …”
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    Detection and counting of pigment glands in cotton leaves using improved U-Net
  7. 14647
    “…This entire process is time-consuming, laborious, and challenging for pathologists. The modern use of whole-slide imaging, which scans histopathology slides to digital slices, and analysis using computer-aided diagnosis is an essential problem. …”
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    A semi-supervised learning approach with consistency regularization for tumor histopathological images analysis
  8. 14648
    “…The current European legislation only allows disposing of these effluents directly into the waterways with previous treatment, which is laborious and expensive. Therefore, as much as possible, these by‐products are reutilized as animal feed material and, if not applicable, used as fertilizers adding phosphorus, potassium, nitrogen, and other nutrients to the soil. …”
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    Utilization of salt‐rich by‐products from the dairy industry as feedstock for recombinant protein production by Debaryomyces hansenii
  9. 14649
    “…Increasing crop yields through plant breeding is time consuming and laborious, with the generation of novel combinations of alleles being limited by chromosomal linkage blocks and linkage‐drag. …”
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    Identification, characterization, and rescue of CRISPR/Cas9 generated wheat SPO11‐1 mutants
  10. 14650
    por Yadav, Manisha, Eswari, J. Satya
    Publicado 2023
    “…Generating the library of compounds and studies for target specificity and ADMET (Absorption, Distribution, Metabolism, Excretion and Toxicity) for large molecules are laborious and incur huge cost and chemical wastage through in-vitro methods. …”
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    Opportunistic Challenges of Computer-aided Drug Discovery of Lipopeptides: New Insights for Large Molecule Therapeutics
  11. 14651
    “…However, a main bottleneck for their general implementation resides in the time-consuming, laborious, and highly-specialized techniques employed for the manufacturing and assessing of these therapies, excessively increasing their prices and delaying their administration to the patients. …”
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    Biomimetic nanoplasmonic sensor for rapid evaluation of neutralizing SARS-CoV-2 monoclonal antibodies as antiviral therapy
  12. 14652
    “…Sarcopenia can be diagnosed through medical images-based body part analysis, which requires laborious and time-consuming outlining of irregular contours of abdominal body parts. …”
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    Detection of sarcopenia using deep learning-based artificial intelligence body part measure system (AIBMS)
  13. 14653
    por Wang, Siyuan, Ma, Wenjun, Zhan, Jieyu
    Publicado 2022
    “…(ii) The generation of the mass function for each criterion relies on the empirical judgments of experts, making it time-consuming and laborious in terms of the MCDM problem for large-scale DAs. …”
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    A Clustering Multi-Criteria Decision-Making Method for Large-Scale Discrete and Continuous Uncertain Evaluation
  14. 14654
    “…Moreover, it is difficult to disclose the operation mechanism of devices as the operation is time-consuming and laborious. Therefore, numerical simulation was used in this study to reveal the mechanism of the walnut shell-kernel winnowing device. …”
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    Technological parameter optimization for walnut shell-kernel winnowing device based on neural network
  15. 14655
    “…CONCLUSION: This method is useful to compare overall rates as an additional information when RTGC Report Table is been used or, for some type of studies as analytical ecologic studies with multiple groups, where leading with the report tables are laborious and hard to interpret. The use of Robson Ten Group Classification for direct standardization of cesarean rates is easy to apply and interpret. …”
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    Direct standardization method according to Robson classification for comparison of cesarean rates
  16. 14656
    “…This study proposes four universality classes of novel consensus scoring (CS) algorithms that combine docking scores, derived from ten docking programs (ADFR, DOCK, Gemdock, Ledock, PLANTS, PSOVina, QuickVina2, Smina, Autodock Vina and VinaXB), using decoys from the DUD-E repository (http://dude.docking.org/) against 29 MRSA-oriented targets to create a general VS formulation that can identify active ligands for any suitable protein target. …”
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    Towards Effective Consensus Scoring in Structure-Based Virtual Screening
  17. 14657
    por Luo, Xinhui, Zhang, Lichun, Chen, Songlin
    Publicado 2023
    “…This strategy to develop polymorphic SSR markers not only obtained a large set of polymorphic SSRs but also eliminated the need for laborious experimental screening. SSR markers developed in this study may facilitate blackhead seabream research, which lays a certain foundation for further gene tagging and genetic linkage analysis, such as marker-assisted selection, genetic mapping, as well as comparative genomic analysis.…”
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    Microsatellite Genome-Wide Database Development for the Commercial Blackhead Seabream (Acanthopagrus schlegelii)
  18. 14658
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    Dimensionality reduction reveals separate translation and rotation populations in the zebrafish hindbrain
  19. 14659
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    Is 25OH Vitamin D Excess before 36 Weeks Corrected Age an Independent Risk Factor for Bronchopulmonary Dysplasia or Death?
  20. 14660
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    Health-related rehabilitation services: assessing the global supply of and need for human resources
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