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  1. 14941
    “…In these cases, the ability to compare the effects of one or more custom matrices may be needed. This laborious process is often performed manually because the ability to simultaneously load multiple matrices and then compare their effects on alignments is not readily available in current software tools. …”
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  2. 14942
    “…Even though the knowledge graph is based on information that was already published in other articles about immunology, the system we present is more efficient than the laborious task of manually reading all the literature to find indirect or implicit relations. …”
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  3. 14943
    “…BACKGROUND & OBJECTIVES: A rapid and simple alternative method is needed to replace the laborious, time-consuming Salmonella serotyping. The objective of the present study was to improve and simplify a previously reported multiplex polymerase chain reaction (PCR)-based method and to create an online server to enable rapid determination of serovars. …”
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  4. 14944
    “…Etest, disc diffusion and agar dilution methods are subjective, mostly laborious for large-scale testing and take ∼24 h. We aimed to develop a rapid broth microdilution assay using resazurin (blue), which is converted into resorufin (pink fluorescence) in the presence of viable bacteria. …”
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  5. 14945
    “…Time integrated ɛHf[t] compositional array of the Hadean xenocrysts indicates a mafic protolith with (176)Lu/(177)Hf ratio of ∼0.019 that was reworked during ∼4.2-4.0 Ga. This also suggests that separation of such an enriched reservoir from chondritic mantle took place at 4.5 ± 0.19 Ga. …”
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  6. 14946
    “…Currently, manually measuring plant height is laborious and has become a bottleneck for genetics and breeding programs. …”
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  7. 14947
    “…The method is fully “top-down”, that is, without laborious in situ enzymatic digestion that typically disturbs the detection of low-abundance endogenous peptides by MSI. …”
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  8. 14948
    “…When combined with an internal standard, MRM allows absolute quantification of proteins in virtually any type of sample but the development and validation of an MRM assay for a specific protein is laborious. Therefore, several public repositories now host targeted proteomics MRM assays, including NCI’s Clinical Proteomic Tumor Analysis Consortium assay portals, PeptideAtlas SRM Experiment Library, SRMAtlas, PanoramaWeb and PeptideTracker, with all of which contain different levels of information. …”
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  9. 14949
    “…These data include: sedimentary rock associations inferred to have accumulated in passive continental margin settings, marking the onset of sea-floor spreading; the oldest foreland basin deposits associated with lithospheric convergence; a change from thin, new continental crust of mafic composition to thicker crust of intermediate composition, increased crustal reworking and the emplacement of potassic and peraluminous granites, indicating stabilization of the lithosphere; replacement of dome and keel structures in granite-greenstone terranes, which relate to vertical tectonics, by linear thrust imbricated belts; the commencement of temporally paired systems of intermediate and high dT/dP gradients, with the former interpreted to represent subduction to collisional settings and the latter representing possible hinterland back-arc settings or ocean plateau environments. …”
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  10. 14950
    “…This explosion of sequence data creates a huge gap among the domains of sequence structure and function, since the experimental techniques to determine the structure and function are very expensive, time taking, and laborious in nature. Therefore, there is an urgent need to emphasize on the development of computational approaches in the field of biological systems. …”
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  11. 14951
    por Shen, Cong, Ding, Yijie, Tang, Jijun, Guo, Fei
    Publicado 2019
    “…They play an important role in regulating gene expression by interacting with the homologous RNA-binding proteins. Due to the laborious and time-consuming nature of wet experimental methods, more researchers should pay great attention to computational approaches for the prediction of lncRNA-protein interaction (LPI). …”
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  12. 14952
  13. 14953
    “…Manual methods of recording such information are slow, often involve laborious transcription from hand-written notes or the need to have a laptop or tablet on site, and present a risk by separating written data capture from image capture. …”
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  14. 14954
  15. 14955
    “…OBJECTIVE: Assessing risks of bias in randomized controlled trials (RCTs) is an important but laborious task when conducting systematic reviews. …”
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  16. 14956
    “…Isolated mandibular fractures were the most common [48.6% (parasymphysis 31.6%, condyle 28.2%)], followed by midface with maxilla fracture [27.6% (zygomatic bone and arch 50.2% and Lefort II fractures 18%)]. Treatment modalities were conservative management, closed reduction, and open reduction with internal fixation under GA/LA. …”
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  17. 14957
    “…The bathymetry of nearshore coastal environments and lakes is constantly reworking because of the change in the patterns of energy dispersal and related sediment transport pathways. …”
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  18. 14958
    “…However, mesopic and dark-adapted two-color fundus-controlled perimetry (FCP, also called “microperimetry”) constitute laborious examinations. We have devised a machine-learning-based approach to predict mesopic and dark-adapted (DA) retinal sensitivity in eyes with neovascular age-related macular degeneration (nAMD). …”
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  19. 14959
    “…Standard toxicity tests on plants are laborious, demanding in terms of space and material, and the measurement of growth-inhibition based endpoints takes relatively long time. …”
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  20. 14960
    por Baddireddy, Kavya, Poojary, Shital
    Publicado 2019
    “…Conventional methods such as potassium hydroxide (KOH) mount lack color contrast and require a trained eye, whereas fungal culture is laborious and costly. Chicago sky blue 6B (CSB) a new contrast stain promises to be a reliable and rapid diagnostic method. …”
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