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  1. 14961
    “…When comparing these two, the high-intensity ultra-sonication protocol was less laborious, faster and allowed to extract 3.5 times more RNA compared to the liquid nitrogen pestle protocol. …”
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    Development of a new extraction method based on high-intensity ultra-sonication to study RNA regulation of the filamentous cyanobacteria Planktothrix
  2. 14962
    “…Yet, most previously published studies have been restricted by the laborious techniques (like electron microscopy) and the limited availability of centriolar markers, resulting in small-scale studies and the lack of solid causational evidence. …”
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    The Role of Sperm Centrioles in Human Reproduction – The Known and the Unknown
  3. 14963
    “…Improving medication adherence is urgently needed but remains laborious, given the numerous and multidimensional reasons for non-adherence, suggesting the need for measurement-guided, multifactorial and individualized solutions. …”
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    Determinants, consequences and potential solutions to poor adherence to anti-osteoporosis treatment: results of an expert group meeting organized by the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases (ESCEO) and the International Osteoporosis Foundation (IOF)
  4. 14964
    “…Routine STMS analysis involving low-throughput, laborious and time-consuming polyacrylamide/agarose gels often limit their full utility in crop breeding experiments that involve large populations. …”
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    GLADS: A gel-less approach for detection of STMS markers in wheat and rice
  5. 14965
    “…The predominance of phosphatic coated grains within phoshorites indicates reworking in shallow water environments. Raman spectroscopy reveals that the phosphorites contain organic carbon, and petrographic and scanning electron microscopic analyses reveal that the phosphorites contain putative microfossils, potentially suggesting microbial involvement in a direct or indirect way. …”
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    Uppermost Triassic phosphorites from Williston Lake, Canada: link to fluctuating euxinic-anoxic conditions in northeastern Panthalassa before the end-Triassic mass extinction
  6. 14966
    “…A process for locating parathyroid glands was utilized to stratify gland dissection laboriousness. In Type A, the gland is firmly fixed to thyroid gland. …”
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    Comparison of parathyroid hormone kinetics in endoscopic thyroidectomy via bilateral areola with open thyroidectomy
  7. 14967
    “…We show that (i) the spectra alone allows good discrimination of the samples based on rheology, (ii) 3D-PCA allows comprehensive and informative visualization of the data, and (iii) that the rheological parameters are predicted accurately using a regression method such as PLSR; instead of using chemical parameters which are laborious to obtain, Mid-FTIR spectra gathering all physicochemical information could be used for efficient prediction of firmness. …”
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    Use of Machine Learning and Infrared Spectra for Rheological Characterization and Application to the Apricot
  8. 14968
    “…Experimental methodologies used before the genomic era were insufficient, too laborious and time-consuming to recover the collection of all satDNAs from a genome. …”
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    De novo identification of satellite DNAs in the sequenced genomes of Drosophila virilis and D. americana using the RepeatExplorer and TAREAN pipelines
  9. 14969
    “…Given the high image resolution and dimensions, its estimation by expert clinicians is particularly laborious and time consuming. Though automatic cell counting techniques have been presented so far, the problem is still open. …”
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    ki67 nuclei detection and ki67-index estimation: a novel automatic approach based on human vision modeling
  10. 14970
    “…However, the manual annotation and qualitative interpretation of reactivity across these large datasets can be nuanced, laborious, and difficult for new practitioners. We developed a quantitative and systematic approach to automatically detect RNA folding events from these datasets to reduce human bias/error, standardize event discovery and generate hypotheses about RNA folding trajectories for further analysis and experimental validation. …”
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    DUETT quantitatively identifies known and novel events in nascent RNA structural dynamics from chemical probing data
  11. 14971
    “…Here, we investigate how faunal activity (sediment particle reworking and bioirrigation) in communities that have survived contrasting levels of bottom fishing affect sediment organic carbon content and macronutrient concentrations ([NH(4)–N], [NO(2)–N], [NO(3)–N], [PO(4)–P], [SiO(4)–Si]). …”
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    Mediation of macronutrients and carbon by post-disturbance shelf sea sediment communities
  12. 14972
    “…Risk reduction options include appropriate site selection for poplar plantations, avoiding wounds, and debarking wood. The main uncertainties concern the distribution of the pathogen in the EU, the susceptibility of cultivated hybrid poplars to the pathogen and thus the potential damage to poplar plantations in the RA area. …”
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    Pest categorisation of Entoleuca mammata
  13. 14973
    por Guo, Yanfei, Peng, Yanjun
    Publicado 2020
    “…But the traditional manual method of retinal blood vessel segmentation is not only time-consuming and laborious but also cannot guarantee the accuracy and efficiency of diagnosis. …”
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    BSCN: bidirectional symmetric cascade network for retinal vessel segmentation
  14. 14974
    “…Laboratory methods are laborious and technically challenging, which is impractical during emergencies. …”
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    Agreement of stall‐side and laboratory major crossmatch tests with the reference standard method in horses
  15. 14975
    “…This creates a problem for authorities in elucidating accurate species identification without the laborious task of incubation and hand rearing until a morphological identification can be made. …”
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    Egg forensics: An appraisal of DNA sequencing to assist in species identification of illegally smuggled eggs
  16. 14976
    “…The former was less laborious with shorter time for completion and can easily be adapted to an automated system such as the MagNa Pure-LC, which can extract nucleic acid from clinical samples and load it into the sample capillaries of the LightCycler™. …”
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    Comparison of 9 different PCR primers for the rapid detection of severe acute respiratory syndrome coronavirus using 2 RNA extraction methods
  17. 14977
    “…Photosynthesis is currently measured using time-laborious and/or destructive methods which slows research and breeding efforts to identify crop germplasm with higher photosynthetic capacities. …”
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    Plot-level rapid screening for photosynthetic parameters using proximal hyperspectral imaging
  18. 14978
    “…These new approaches are disrupting the traditional and manual art form of prosthetic production which are laborious and costly and are being replaced by more precise and quantitative processes which enable the rapid, low cost production of patient-specific prostheses. …”
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    Advancements in Soft-Tissue Prosthetics Part A: The Art of Imitating Life
  19. 14979
    “…Overall, our results demonstrate the utility of the on-line method in providing site-specific structural information of charge modifications without fraction collection and laborious peptide mapping.…”
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    Characterization of therapeutic proteins by cation exchange chromatography-mass spectrometry and top-down analysis
  20. 14980
    por Wu, Di, Cai, Zhen, Han, Jiwan, Qin, Huawei
    Publicado 2020
    “…Manual assessment of kernel traits can be time consuming and laborious. Moreover, manually acquired data can be influenced by subjective bias of the observer. …”
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    Automatic kernel counting on maize ear using RGB images
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