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  1. 15001
    “…The 24-hour urine free cortisol (UFC) measurement is considered gold standard. This is a laborious test, dependent on correct urine collection. …”
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    Bedtime Salivary Cortisol as a Screening Test for Cushing Syndrome in Children
  2. 15002
    “…This enabled us to measure luminescence intensities instead of counting beating cardiomyocytes, which is less labor intensive. We established two NKX2.5 reporter cell lines and validated their pluripotency and genetic stability. …”
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    Creating a human-induced pluripotent stem cell-based NKX2.5 reporter gene assay for developmental toxicity testing
  3. 15003
    “…BACKGROUND: Diagnostic neurovascular imaging data are important in stroke research, but obtaining these data typically requires laborious manual chart reviews. OBJECTIVE: We aimed to determine the accuracy of a natural language processing (NLP) approach to extract information on the presence and location of vascular occlusions as well as other stroke-related attributes based on free-text reports. …”
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    Automating Stroke Data Extraction From Free-Text Radiology Reports Using Natural Language Processing: Instrument Validation Study
  4. 15004
    “…For comparison purposes, a reworked Van Der Wijk model (RVDM) was used in the same method and compared to the MVDM. …”
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    New Method to Predict the Viscosity of Bitumen Diluted with Light Oil Using a Modified Van Der Wijk Model under Reservoir Temperature and Pressure
  5. 15005
    “…With the increasing number of pharmaceuticals and the complexity of the pharmaceutical manufacturing supply chain, monitoring for substandard medicines via manual environmental scanning can be laborious and time consuming. METHODS: A web crawler was developed to automatically detect and extract alerts on substandard medicines published on the Internet by regulatory agencies. …”
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    Augmenting Product Defect Surveillance Through Web Crawling and Machine Learning in Singapore
  6. 15006
    “…Conventional bacterial culture methods for detecting foodborne pathogens are time-consuming, laborious, and lacking in pathogen diagnosis. To overcome this problem, we have created an embedded paper-based microchip based on isothermal loop amplification (LAMP), which can rapidly and sensitively detect foodborne pathogens. …”
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    A newly developed paper embedded microchip based on LAMP for rapid multiple detections of foodborne pathogens
  7. 15007
    “…Conclusion: MDJ fractures can be reduced successfully and fixed stably via a novel CRPP technique, and laborious and frustrating attempts at closed reduction and further open reduction can be avoided.…”
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    Closed Reduction and Percutaneous Pinning in the Treatment of Humeral Distal Metaphyseal-Diaphyseal Junction Fractures in Children: A Technique Note and Preliminary Results
  8. 15008
    “…A single-bed system, commonly used in micro-PET, is laborious to use in large-scale studies. Here, we evaluated the image qualities of a multi-bed system. …”
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    Validation of Image Qualities of a Novel Four-Mice Bed PET System as an Oncological and Neurological Analysis Tool
  9. 15009
    “…Without the use of a visualisation and interpretation pipeline this step can be time consuming and laborious, and is often completed using R. Though commercial visualisation and interpretation pipelines are comprehensive, freely available pipelines are currently more limited. …”
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    Searchlight: automated bulk RNA-seq exploration and visualisation using dynamically generated R scripts
  10. 15010
    “…OBJECTIVES: RT-PCR assay is the reference method for diagnosis of COVID-19, but it is also a laborious and time-consuming technic, limiting the availability of testing. …”
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    Clinitest rapid COVID-19 antigen test for the diagnosis of SARS-CoV-2 infection: A multicenter evaluation study
  11. 15011
    por Lee, Joo Young, Han, Se Jin
    Publicado 2021
    “…OBJECTIVES: The purpose of this study was to evaluate the postoperative anteroposterior stability and improvements in facial asymmetry after performing LeFort I osteotomy in the maxilla, sagittal split ramus osteotomy (SSRO) and intraoral vertical ramus osteotomy (IVRO) in the mandible, and lateral corticectomy on the IVRO side. …”
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    Sagittal split ramus osteotomy, intraoral vertical ramus osteotomy, and lateral corticectomy for asymmetric mandibular prognathism
  12. 15012
    “…In conclusion, the SARS-CoV-2 NP ELISA is a suitable laboratory diagnostic test for COVID-19, particularly for hospitals, where blood samples are readily available and screening of serum or plasma by ELISA can facilitate prevention of nosocomial infections and reduce the requirement for laborious swab sampling and subsequent PCR analysis to confirmatory tests only.…”
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    Early Laboratory Diagnosis of COVID-19 by Antigen Detection in Blood Samples of the SARS-CoV-2 Nucleocapsid Protein
  13. 15013
    “…Unfortunately classical neutralization assays are laborious, time-consuming and require an adequate biosafety level laboratory. …”
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    Two novel SARS-CoV-2 surrogate virus neutralization assays are suitable for assessing successful immunization with mRNA-1273
  14. 15014
    por Fan, Yongxian, Wang, Wanru
    Publicado 2021
    “…More importantly, accurately identifying the origin of replication has great application value in the diagnosis and treatment of diseases related to genetic information errors, while the traditional biological experimental methods are time-consuming and laborious. RESULTS: We carried out research on the origin of replication in a variety of eukaryotes and proposed a unique prediction method for each species. …”
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    Using multi-layer perceptron to identify origins of replication in eukaryotes via informative features
  15. 15015
    “…Despite the refinement of software tools and algorithms, significant programming expertise is often required to analyze large optical data sets, and data analysis can be laborious and time-consuming. To address this challenge, we developed an accessible, open-source software script that is untethered from any subscription-based programming language. …”
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    KairoSight: Open-Source Software for the Analysis of Cardiac Optical Data Collected From Multiple Species
  16. 15016
    “…The traditional method to evaluate the wheat injury caused by the freezing stress is by visual observations, which is time-consuming and laborious. Therefore, a more efficient and accurate method for freezing damage identification is urgently needed. …”
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    A method for obtaining field wheat freezing injury phenotype based on RGB camera and software control
  17. 15017
    “…Although molecular techniques can accurately distinguish between mosquito species, they are costly and laborious, making them unsuitable for extensive use in the field. …”
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    Geometric morphometric wing analysis as a tool to discriminate female mosquitoes from different suburban areas of Chiang Mai province, Thailand
  18. 15018
    “…The common method to screen high-producing colonies is SDS-PAGE, a laborious and time-consuming process, which is based on a random and qualitative way. …”
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    Rapid screening of high expressing Escherichia coli colonies using a novel dicistronic-autoinducible system
  19. 15019
    “…In comparison to the ‘gold standard’ assays (virus neutralization titers (VNT) or plaque reduction neutralization titers (PRNT)), which are laborious and time consuming and require special containment measures due to their use of live viruses. …”
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    Detection and Quantification of SARS-CoV-2 Receptor Binding Domain Neutralization by a Sensitive Competitive ELISA Assay
  20. 15020
    por Li, Ziyi, Feng, Hao
    Publicado 2022
    “…The traditional approach of annotating cell types based on unsupervised clustering and marker genes is time-consuming and laborious. Taking advantage of the numerous existing scRNA-seq databases, many supervised label assignment methods have been developed. …”
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    A neural network-based method for exhaustive cell label assignment using single cell RNA-seq data
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