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15081por Sadeghi, Amir, Masjedi Arani, Abbas, Karami Khaman, Hosna, Qadimi, Arezoo, Ghafouri, Raziyeh“…Regarding the improvement of clinical processes, elimination of reworks can increase satisfaction in nurses (P<0.01). …”
Publicado 2023
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15082“…Considering wet-lab experiment is time-consuming, laborious, and expensive, in silico prediction of metabolic stability is an alternative choice. …”
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15083por Basso, Matthew Nicholas, Barua, Moumita, Meyer, Julien, John, Rohan, Khademi, April“…These methods can be laborious, costly, fraught with inter-observer variability, and can have delays in turn-around time. …”
Publicado 2022
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15084por AlMohtasib, Jamil, Al-Huneidy, Leen, Taha, Hana, Rayyan, Rama, Mansour, Shahd, Samhouri, Jehad, Hammouri, Muhammad, Al-Somadi, Hussam, Bedros, Adees Wirtan, Al-Omairi, Jaafar, Abbas, Rand, Abu-usba, Mustafa Ibrahim, Al-Ani, Abdallah“…CONCLUSION: The Jordanian medical research landscape is riddled with all forms of different barriers. The reworking of current and integration of new research training programs are of utmost importance.…”
Publicado 2023
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15085por Tezier, Benjamin, Van Hoye, Aurélie, Vuillemin, Anne, Lemonnier, Fabienne, Rostan, Florence, Guillemin, Francis“…The results and feedback from the project leaders enabled the intervention steps to be reworked and an evaluation design to be developed for future work. …”
Publicado 2023
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15086“…INTRODUCTION: There is a need to explore less laborious point-of-care assessment tools to diagnose protein energy wasting (PEW) in children with chronic kidney disease (CKD). …”
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15087por Sonnenberg, Anton S. M., Sedaghat-Telgerd, Narges, Lavrijssen, Brian, Hendrickx, Patrick M., Scholtmeijer, Karin, Baars, Johan J. P., Visser, Richard G. F., van Peer, Arend“…This phenotype can only be assessed in the meiotic offspring of an intervarietal hybrid which is a laborious and difficult task. Nevertheless, this was done, and we were able to map three QTLs for this trait, two on chromosome 1 and one on chromosome 2 not overlapping with the QTL for BSN. …”
Publicado 2021
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15088por Yan, Ling, Xuan, Fang-Ling, Chen, Song, Gou, Mengzhuang, Chen, Wenjin, Li, Yanli, Wang, Zhiren, Wang, Leilei, Xie, Ting, Fan, Fengmei, Zharkovsky, Alexander, Tan, Yunlong, Tian, Li“…We further studied a cohort of first-episode schizophrenia (FES, n = 74) patients who had higher perceived stress scores (PSS) than healthy controls (HCs, n = 68). RESULTS: Reborn microglia attenuated CUS-induced learned hopelessness and social withdrawal but not anxiety in mice. …”
Publicado 2023
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15089por Szot-Karpińska, Katarzyna, Kudła, Patryk, Orzeł, Urszula, Narajczyk, Magdalena, Jönsson-Niedziółka, Martin, Pałys, Barbara, Filipek, Sławomir, Ebner, Andreas, Niedziółka-Jönsson, Joanna“…Such an approach has not been reported previously for peptide screening and demonstrates a new trend in science where calculations can replace or support laborious experimental techniques. Finally, the best CRP binder—the P3 peptide—was used for CRP recognition on silicate-modified indium tin oxide-coated glass electrodes. …”
Publicado 2023
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15090por den Boer, Robin, Siang, Kelvin Ng Wei, Yuen, Mandy, Borggreve, Alicia, Defize, Ingmar, van Lier, Astrid, Ruurda, Jelle, van Hillegersberg, Richard, Mook, Stella, Meijer, Gert“…However, manual tumor delineation is labor intensive and subjective. Furthermore, noise in DW-MRI images will propagate into the corresponding apparent diffusion coefficient (ADC) signal. …”
Publicado 2023
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15091por Gransbury, Gemma K., Corner, Sophie C., Kragskow, Jon G. C., Evans, Peter, Yeung, Hing Man, Blackmore, William J. A., Whitehead, George F. S., Vitorica-Yrezabal, Iñigo J., Oakley, Meagan S., Chilton, Nicholas F., Mills, David P.“…However, gauging the crossover point at which the Cp(R) substituents are large enough to prevent equatorial ligand binding, but small enough to approach the metal closely and generate strong crystal field splitting has required laborious synthetic optimization. We therefore created the computer program AtomAccess to predict the accessibility of a metal binding site and its ability to accommodate additional ligands. …”
Publicado 2023
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15092“…BACKGROUND: Gene knock‐in (KI) in animal cells via homology‐directed repair (HDR) is an inefficient process, requiring a laborious work for screening from few modified cells. …”
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15093“…The method is far less laborious and possesses several advantages over direct measurement of individual cells. …”
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15094“…In addition, currently used standard methods such as electrolyte leakage assays are very laborious and therefore not easily applicable for large-scale screening purposes. …”
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15095“…Detection of total V. parahaemolyticus using conventional culture- and biochemical-based assays is time-consuming and laborious, requiring more than three days. Thus, we developed a novel and highly specific loop-mediated isothermal amplification (LAMP) assay for the sensitive and rapid detection of Vibrio parahaemolyticus. …”
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15096“…The relative expression of PPAR gamma, adiponectin, and leptin in 3T3-L1 adipocytes was quantified densitometrically using the software LabWorks 4.5, and calculated according to the reference bands of beta-actin. …”
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15097por Wen, Yongping, Cheng, Anchun, Wang, Mingshu, Ge, Han, Shen, Chanjuan, Liu, Sitong, Xiang, Jun, Jia, Renyong, Zhu, Dekang, Chen, Xiaoyue, Lian, Bei, Chang, Hua, Zhou, Yi“…The diagnosis of DP currently relies on the use of live or inactivated whole DPV virion as antigens in ELISA, but it is too laborious and expensive for routine application, and it is still difficult to get purified DPV virion with current technology. …”
Publicado 2010
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15098por Ihssen, Julian, Kowarik, Michael, Dilettoso, Sandro, Tanner, Cyril, Wacker, Michael, Thöny-Meyer, Linda“…State-of-the art production of conjugate vaccines using chemical methods is a laborious, multi-step process. In vivo enzymatic coupling using the general glycosylation pathway of Campylobacter jejuni in recombinant Escherichia coli has been suggested as a simpler method for producing conjugate vaccines. …”
Publicado 2010
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15099“…Current diagnostic screening strategies based on karyotyping or fluorescent in situ hybridization (FISH) for detection of chromosomal abnormalities in chronic lymphocytic leukemia (CLL) are laborious, time-consuming, costly, and have limitations in resolution. …”
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15100“…However, identifying micro-and minisatellite markers on large sequence data sets is often a laborious process. RESULTS: FONZIE was designed to successively 1) perform a search for markers via the external software Tandem Repeat Finder, 2) exclude user-defined specific genomic regions, 3) screen for the size and the percent matches of each relevant marker found by Tandem Repeat Finder, 4) evaluate marker specificity (i.e., occurrence of the marker as a single copy in the genome) using BLAST2.0, 5) design minisatellite primer pairs via the external software Primer3, and 6) check the specificity of each final PCR product by BLAST. …”
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