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  1. 15221
    “…The MAD could improve laborious and time-consuming derivatization procedure, since dielectric heating using microwave directly increase molecular energy of reactants by penetrating through medium. …”
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    Profiling of Steroid Metabolic Pathways in Human Plasma by GC-MS/MS Combined with Microwave-Assisted Derivatization for Diagnosis of Gastric Disorders
  2. 15222
    “…The recovery of NTM from environmental samples can be a laborious undertaking and current pre-treatment methods and selective media lack sensitivity. …”
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    Evaluation of a new culture medium for isolation of nontuberculous mycobacteria from environmental water samples
  3. 15223
    “…For long term storage, controlling the moisture content level in grains is challenging because existing moisture measuring techniques are time-consuming and laborious as measurements are carried out manually. …”
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    RF-Based Moisture Content Determination in Rice Using Machine Learning Techniques
  4. 15224
    “…Combined with internal standards, the method achieves very good repeatability and reproducibility enabling excellent protein quantification and allowing longitudinal and cohort studies. A laborious part of performing such experiments lies in the preparation steps dedicated to the development and validation of individual protein assays. …”
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    An Update on MRMAssayDB: A Comprehensive Resource for Targeted Proteomics Assays in the Community
  5. 15225
    “…Conventional methods for drainage mapping such as tile probes and trenching equipment are laborious, cause pipe damage, and are often inefficient to apply at large spatial scales. …”
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    Mapping of Agricultural Subsurface Drainage Systems Using Unmanned Aerial Vehicle Imagery and Ground Penetrating Radar †
  6. 15226
    “…BACKGROUND: Morphologic rare cell detection is a laborious, operator-dependent process which has the potential to be improved by the use of image analysis using artificial intelligence. …”
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    Image Analysis Using Machine Learning for Automated Detection of Hemoglobin H Inclusions in Blood Smears – A Method for Morphologic Detection of Rare Cells
  7. 15227
    “…However, CMR is expensive, laborious, and has only limited availability. In comparison, transthoracic echocardiography (TTE) is widely available and cost‐efficient. …”
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    Exploratory echocardiographic strain parameters for the estimation of myocardial infarct size in ST‐elevation myocardial infarction
  8. 15228
    “…Disease prevention relies on the so-called “Infection and Treatment Method” (ITM), which is costly, complex, laborious, difficult to standardise on a commercial scale and results in a parasite strain-specific, MHC class I-restricted cytotoxic T cell response. …”
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    Development of a Potential Yeast-Based Vaccine Platform for Theileria parva Infection in Cattle
  9. 15229
    “…HowRU uses the video conferencing platform Webex with the integration of some newly designed software that automates many of the laborious and complex processes. HowRU is a cloud based, supported, and simplified system that closely simulates open and flexible visiting while ensuring patient and family privacy, dignity, and security. …”
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    Developing an Innovative System of Open and Flexible, Patient-Family-Centered, Virtual Visiting in ICU During the COVID-19 Pandemic: A Collaboration of Staff, Patients, Families, and Technology Companies
  10. 15230
    “…This test has previously been used to detect MAP in cattle blood following the purification of buffy coat using Ficoll gradients, however this method is quite laborious and costly. The purpose of this study was to develop a simpler method of blood preparation that was also compatible with deer blood and the Actiphage test. …”
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    Development of a Method to Detect Mycobacterium paratuberculosis in the Blood of Farmed Deer Using Actiphage® Rapid
  11. 15231
    “…Hence, we used automated home-cage monitoring LABORAS to evaluate spontaneous locomotive behaviors in LPS-induced mice. …”
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    Automated home-cage monitoring as a potential measure of sickness behaviors and pain-like behaviors in LPS-treated mice
  12. 15232
    “…Traditional drainage method is considered laborious and gravity-dependent. In this study, we aimed to evaluate the clinical effect of a modified multifunctional irrigation-assisted vacuum drainage (MIVD) by comparing it with the traditional drainage method in the treatment of odontogenic deep fascial infection. …”
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    Multifunctional Irrigation-Assisted Vacuum Drainage versus Traditional Drainage in the Treatment of Odontogenic Deep Fascial Infection: A Retrospective Cohort Study
  13. 15233
    “…Infant, preschool, and school programs were most often targeted for catch-up through measures such as appointment rebooking and making additional clinics and/or providers available. …”
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    Continuity of routine immunization programs in Canada during the COVID-19 pandemic
  14. 15234
    “…Improving feedback quality is laborious and only modestly effective. APPROACH: The authors developed the LEAF (Learner-Engaged Analysis of Feedback) method to improve learner satisfaction with, and reflection on, existing written feedback. …”
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    Doing More With Written Feedback: Improving Learner Satisfaction and Reflection With the LEAF (Learner-Engaged Analysis of Feedback) Method
  15. 15235
    “…An IBD vaccine is produced in Ethiopia using primary chicken embryo fibroblast (CEF) cell, which is time-consuming, laborious, and uneconomical. The present study was carried out to develop cell-based IBDV LC-75 vaccine using Vero cells and to evaluate the safety, immunogenicity and protection level. …”
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    Immunogenicity and Efficacy Evaluation of Vero Cell-Adapted Infectious Bursal Disease Virus LC-75 Vaccine Strain
  16. 15236
    “…CONCLUSIONS: The data offer cautious support for use of next-generation QVOAs as proxies for more laborious QVOA, while providing greater sensitivities and dynamic ranges. …”
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    Assessing the Suitability of Next-Generation Viral Outgrowth Assays to Measure Human Immunodeficiency Virus 1 Latent Reservoir Size
  17. 15237
    “…This was most closely related to R. leporis, R. guilhoni and R. linnaei. The adult ticks and a small proportion of nymphs clustered with R. camicasi sequences from a previous study. …”
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    Automatic barcode gap discovery reveals diverse clades of Rhipicephalus spp. and Haemaphysalis spp. ticks from small mammals in 'Asir, Saudi Arabia
  18. 15238
    “…New diagnostic methods such as LED fluorescence microscopy, Genexpert, Interferon Gamma Release Assay (IGRA) are limited on efficacy spectrum owing to their high cost, time-intensive and laborious nature, in addition their low sensitivity hinders their robustness and portability. …”
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    Graphene Oxide Based Electrochemical Genosensor for Label Free Detection of Mycobacterium tuberculosis from Raw Clinical Samples
  19. 15239
    “…Breeding alfalfa for herbage accumulation (HA) requires frequent and multiple phenotyping efforts, which is laborious and costly. The objective of this study was to assess the efficiency of UAV-based imagery and spatial analysis in the selection of alfalfa for HA. …”
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    Phenomics-Assisted Selection for Herbage Accumulation in Alfalfa (Medicago sativa L.)
  20. 15240
    “…Conventional deep learning (DL) algorithm requires full supervision of annotating the region of interest (ROI) that is laborious and often biased. We aimed to develop a weakly-supervised DL algorithm that diagnosis breast cancer at ultrasound without image annotation. …”
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    Weakly-supervised deep learning for ultrasound diagnosis of breast cancer
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