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15481por Zuo, Wenxuan, Wang, Beibei, Bai, Xin, Luan, Yihui, Fan, Yingying, Michail, Sonia, Sun, Fengzhu“…We also showed that 16S rRNA data yielded accurate disease prediction results in comparison to shotgun data, which can be more expensive and laborious. These conclusions were confirmed in an independent data set of 7 pediatric UC cases and 8 controls.…”
Publicado 2022
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15482por Negri, Timo, Mantri, Shrikant, Angelov, Angel, Peter, Silke, Muth, Günther, Eustáquio, Alessandra S., Ziemert, Nadine“…These strategies, however, often entail laborious, multi-step, and time-consuming procedures to recover the biosynthetic gene clusters (BGCs) from soil metagenomes for subsequent heterologous expression. …”
Publicado 2022
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15483por Li, Mifang, Bai, Hanhua, Zhang, Feiyuan, Zhou, Yujia, Lin, Qiuyu, Zhou, Quan, Feng, Qianjin, Zhang, Lingyan“…Manual tracking of intercondylar notch on MR images is time-consuming and laborious. Deep learning has become a powerful tool for processing medical images. …”
Publicado 2022
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15484por Ray, Debashree, Muñoz, Alvaro, Zhang, Mingyu, Li, Xiuhong, Chatterjee, Nilanjan, Jacobson, Lisa P., Lau, Bryan“…BACKGROUND: Cohort collaborations often require meta-analysis of exposure-outcome association estimates across cohorts as an alternative to pooling individual-level data that requires a laborious process of data harmonization on individual-level data. …”
Publicado 2022
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15485por Catalano, Stefano, La Morgia, Valentina, Molinar Min, Anna Rita, Fanelli, Angela, Meneguz, Pier Giuseppe, Tizzani, Paolo“…Nine helminths were reported on: eight nematodes (Obeliscoides cuniculi, Trichostrongylus calcaratus, Trichostrongylus retortaeformis, Trichostrongylus affinis, Trichuris leporis, Trichostrongylus colubriformis, Passalurus ambiguus, and Nematodirus sp.) and one unidentified cestode. …”
Publicado 2022
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15486por Hua, Ziyi, Li, Shuang, Liu, Qianzi, Yu, Minxuan, Liao, Mengling, Zhang, Hongmei, Xiang, Xuerong, Wu, Qingqing“…However, iMSCs have less osteogenic potential than BMSCs, and the classical iPSC-EB-iMSC process to derive iMSCs from iPSCs is too laborious as it involves multiple in vitro steps. Low-intensity pulsed ultrasound (LIPUS) is a safe therapeutic modality used to promote osteogenic differentiation of stem cells. …”
Publicado 2022
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15487“…However, end-use quality phenotyping is expensive and laborious thus, testing is often delayed until advanced generations. …”
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15488por Ma, Lijiang, Bryce, Nicole S., Turner, Adam W., Di Narzo, Antonio F., Rahman, Karishma, Xu, Yang, Ermel, Raili, Sukhavasi, Katyayani, d’Escamard, Valentina, Chandel, Nirupama, V’Gangula, Bhargavi, Wolhuter, Kathryn, Kadian-Dodov, Daniella, Franzen, Oscar, Ruusalepp, Arno, Hao, Ke, Miller, Clint L., Björkegren, Johan L. M., Kovacic, Jason C.“…The ‘gold standard’ method for understanding causal genes and their mechanisms of action are laborious basic science studies often involving sophisticated knockin or knockout mouse lines, however, these types of studies are impractical as a high-throughput means to understand the many risk variants that cause complex diseases like coronary artery disease (CAD). …”
Publicado 2022
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15489por Chen, Chen, Chen, Cheng, Ma, Mingrui, Ma, Xiaojian, Lv, Xiaoyi, Dong, Xiaogang, Yan, Ziwei, Zhu, Min, Chen, Jiajia“…At present, the classification of histopathological images of liver cancer with different degrees of differentiation has disadvantages such as time-consuming, labor-intensive, and large manual investment. In this context, the importance of intelligent classification of histopathological images is obvious. …”
Publicado 2022
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15490por Karaiyan, Prasanth, Chang, Catherine Ching Han, Chan, Eng-Seng, Tey, Beng Ti, Ramanan, Ramakrishnan Nagasundara, Ooi, Chien Wei“…The in silico gene screening methodology established from this study can increase the success rate of producing soluble and functional enzymes while avoiding the laborious trial and error involved in the screening of a large pool of genes available. …”
Publicado 2022
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15491por Yuan, Chang‐Tsu, Chuang, Shih‐Sung, Cheng, Pei‐Yuan, Chang, Koping, Wang, Hsuan, Tsai, Jia‐Huei, Liau, Jau‐Yu, Chou, Wen‐Chien“…However, the test is laborious and not readily available in some laboratories. …”
Publicado 2022
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15492“…However, the lifetimes of operation of these BPECs are limited, and the preparation is laborious and expensive. We then describe the use of thylakoid membranes in BPECs which requires less effort and usually produces high currents but still suffers from the lack of ability to self-repair damage caused by photoinhibition. …”
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15493por Quinlan, Jonathan I., Jones, Clare, Bissonnette, Emma, Dhaliwal, Amritpal, Williams, Felicity, Choudhary, Surabhi, Breen, Leigh, Lavery, Gareth G., Armstrong, Matthew J., Elsharkawy, Ahmed M., Lord, Janet M., Greig, Carolyn A.“…However, manual segmentation of muscle volume (MV) can be laborious on cross-sectional imaging, due to the number of slices that require analysis. …”
Publicado 2022
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15494por Melidis, Damianos P., Landgraf, Christian, Schmidt, Gunnar, Schöner-Heinisch, Anja, von Hardenberg, Sandra, Lesinski-Schiedat, Anke, Nejdl, Wolfgang, Auber, Bernd“…However, the interpretation of the often large numbers of sequence variants detected when using NGS is laborious, prone to errors and is often difficult to compare across laboratories. …”
Publicado 2022
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15495“…BACKGROUND: Current isolation techniques for spotted fever group Rickettsia from clinical samples are laborious and are limited to tissue, blood and blood derivatives with volumes ideally greater than 1 mL. …”
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15496por Foster, William J., Godbold, Amanda, Brayard, Arnaud, Frank, Anja B., Grasby, Stephen E., Twitchett, Richard J., Oji, Tatsuo“…The body fossils do not, however, record either spatial or temporal changes, because the shell beds represent allochthonous assemblages due to wave reworking. The dominance of small burrow sizes, presence of key taxa including Thalassinoides, Rhizocorallium and Holocrinus, presence of complex trace fossils, and both erect and deep infaunal tiering organisms suggests that the benthic fauna represents an advanced stage of ecological recovery for the Early Triassic, but not full recovery. …”
Publicado 2022
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15497por Chirico, Nino, Kessler, Elise L., Maas, Renée G. C., Fang, Juntao, Qin, Jiabin, Dokter, Inge, Daniels, Mark, Šarić, Tomo, Neef, Klaus, Buikema, Jan-Willem, Lei, Zhiyong, Doevendans, Pieter A., Sluijter, Joost P. G., van Mil, Alain“…So far, several methods have been reported to enhance iPSC-CM maturation; however, these protocols are laborious, costly, and not easily scalable. Therefore, we developed a simple, low-cost, and rapid protocol to promote cardiomyocyte maturation using two small molecule activators of the peroxisome proliferator-activated receptor β/δ and gamma coactivator 1-alpha (PPAR/PGC-1α) pathway: asiatic acid (AA) and GW501516 (GW). …”
Publicado 2022
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15498por de Andrade, Luciano Rogério Braatz, Sousa, Massaine Bandeira e, Wolfe, Marnin, Jannink, Jean-Luc, de Resende, Marcos Deon Vilela, Azevedo, Camila Ferreira, de Oliveira, Eder Jorge“…Genomic selection has been promising in situations where phenotypic assessments are expensive, laborious, and/or inefficient. This work evaluated the efficiency of genomic prediction methods combined with genetic models in clone and parent selection with the goal of increasing fresh root yield, dry root yield, as well as dry matter content in cassava roots. …”
Publicado 2022
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15499por Wang, Jing, Dai, Mingkai, Xing, Xiangling, Wang, Xing, Qin, Xin, Huang, Tao, Fang, Zhiqing, Fan, Yidong, Xu, Dawei“…Recent advances in high‐throughput technologies have enabled the generation of complex datasets, thus providing alternative approaches to exploring telomerase biology more comprehensively, which has proven to be challenging due to the need for laborious assays required to test for telomerase activity. …”
Publicado 2022
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15500“…AIM: The objective is to solve the laborious coding problem for naturalistic hyperscanning by proposing a convenient analytical approach and to uncover brain synchronization mechanisms related to human cooperative behavior when the ultimate goal is highly free and creative. …”
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