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  1. 15761
    “…Neutralization tests are still considered the gold standard for SARS-CoV-2 serological assays, but our assay can identify samples with neutralizing antibodies with 100% sensitivity and 96% specificity without the need for laborious and slow biosafety level 3 (BSL-3) facility-requiring analyses.…”
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    A Highly Sensitive and Specific SARS-CoV-2 Spike- and Nucleoprotein-Based Fluorescent Multiplex Immunoassay (FMIA) to Measure IgG, IgA, and IgM Class Antibodies
  2. 15762
    “…However, this in vivo assay is extremely laborious, expensive, and significantly impairs animal welfare. …”
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    Development of Antibody Detection ELISA Based on Immunoreactive Toxins and Toxin-Derived Peptides to Evaluate the Neutralization Potency of Equine Plasma against Naja atra in Taiwan
  3. 15763
    “…[Image: see text] [Image: see text] CONCLUSION: The single-trough method performed similarly to the more laborious P/T method. No patient would have received a dose adjustment based on the two different AUC estimation methods. …”
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    1107. Vancomycin AUC Dosing: Is One Concentration in the Hand Worth Two in the Bush?
  4. 15764
    “…However, the strategy of prospective audit and feedback is laborious. In Singapore General Hospital (SGH), 10 reviews are required to identify 2 inappropriate cases. …”
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    104. Improving Efficiency of Antimicrobial Stewardship Reviews Using Artificial Intelligence Modelling
  5. 15765
    “…Additionally, we introduce a fast and less labor-intensive steam-debarking method for Salix spp. feedstocks. …”
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    Salix spp. Bark Hot Water Extracts Show Antiviral, Antibacterial, and Antioxidant Activities—The Bioactive Properties of 16 Clones
  6. 15766
    “…The biodosimetry assay could be used as an alternative to the laborious conventional clonogenic assay, while both lymphocytes and cancer cell line could effectively be used for estimation of the biological absorbed dose. …”
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    Comparison and Evaluation of Different Radiotherapy Techniques Using Biodosimetry Based on Cytogenetics
  7. 15767
    “…It is time-consuming and laborious to search for citrus psyllids through artificial patrol, which is inconvenient for the management of citrus orchards. …”
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    Detection Method of Citrus Psyllids With Field High-Definition Camera Based on Improved Cascade Region-Based Convolution Neural Networks
  8. 15768
    “…OBJECTIVES/GOALS: Pressure injuries cause 60,000 deaths and cost $26 billion annually in the US, but prevention is laborious. We used clinical data to develop a machine learning algorithm for predicting pressure injury risk and prescribe the timing of intervention to help clinicians balance competing priorities. …”
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    41250 Machine Learning to Identify Predictors of Iatrogenic Injury Using Empirical Bayes Estimates: A Cohort Study of Pressure Injury Prevention
  9. 15769
    “…While in vivo expression of this cytokine is laborious and lengthy, cell-free or in vitro expression system has the benefits of speed, simplicity, flexibility, focus of all the system energy on target protein synthesis alone, besides high soluble and functional protein yield. …”
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    A De Novo Optimized Cell-Free System for the Expression of Soluble and Active Human Tumor Necrosis Factor-Alpha
  10. 15770
    “…Existing methods for tracking the quality of people’s sleep are laborious and obtrusive. If a method were available that would allow effortless and unobtrusive tracking of sleep quality, it would mark a significant step toward obtaining sleep data for research and clinical applications. …”
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    Tracking Subjective Sleep Quality and Mood With Mobile Sensing: Multiverse Study
  11. 15771
    “…The method, however, is both user-dependent and laborious. In this study, we propose a new automated workflow for counting pitted RBCs using deep neural network analysis. …”
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    Automating Pitted Red Blood Cell Counts Using Deep Neural Network Analysis: A New Method for Measuring Splenic Function in Sickle Cell Anaemia
  12. 15772
    “…The Etest gradient diffusion method can be a reliable alternative for H. pylori AST with the advantage of being a less laborious quantitative method. This work reveals that an optimized Etest method can provide acceptable performance for H. pylori AST and describes the challenges associated with this methodology.…”
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    Multicenter Evaluation of a Gradient Diffusion Method for Antimicrobial Susceptibility Testing of Helicobacter pylori
  13. 15773
    “…With regard to Lp serogrouping, it is well known that phenotyping methods do not have a sufficiently high discriminating power, while genotypic methods although very effective, are expensive and laborious. Recently, mass spectrometry and infrared spectroscopy have proved to be rapid and successful approaches for the microbial identification and typing. …”
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    Use of Fourier-Transform Infrared Spectroscopy With IR Biotyper® System for Legionella pneumophila Serogroups Identification
  14. 15774
    “…However, these techniques are time-consuming, laborious, and always suffer from high false negative rates. …”
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    A Novel Ensemble Learning-Based Computational Method to Predict Protein-Protein Interactions from Protein Primary Sequences
  15. 15775
    “…Thus, our protocol may represent a time-saving filter step prior to laborious confirmation experiments for efflux-driven resistance. …”
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    Identification of Promoter Region Markers Associated With Altered Expression of Resistance-Nodulation-Division Antibiotic Efflux Pumps in Acinetobacter baumannii
  16. 15776
    por LIANG, Yixiao, PAN, Jianzhang, FANG, Qun
    Publicado 2021
    “…However, the current high-throughput screening systems are mainly built based on multiwell plates, which have several disadvantages such as simple cell culture conditions, laborious and time-consuming operation, and high reagent consumption. …”
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    基于微流控技术的细胞水平高通量药物筛选系统的研究进展
  17. 15777
    “…Currently, Cripto-1 detection relies on laborious and time-consuming immunoassays. The reported results demonstrated that the proposed approach based on oriented antibody immobilization was able to significantly improve Cripto-1 detection with a 10-fold enhancement versus the random approach. …”
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    Advanced Lab-on-Fiber Optrodes Assisted by Oriented Antibody Immobilization Strategy
  18. 15778
    “…Currently, the lab supervisors monitor the use of PPE, which is time consuming, laborious, and impossible to see each student. Consequently, students may unintentionally commit unrecognizable unsafe acts, which can lead to unwanted situations. …”
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    Development of YOLOv5-Based Real-Time Smart Monitoring System for Increasing Lab Safety Awareness in Educational Institutions
  19. 15779
    “…Virulence factors and antibitoic resistance genes were identified using Kleborate version 2.0. Hypervirulence was defined as the presence of rmpA or rmpA2 and the aerobactin gene cluster (iuc). …”
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    496. Epidemiology, virulence and antimicrobial resistance of hypervirulent Klebsiella pneumoniae and K. pneumoniae complex member in western New York, 2017-2020
  20. 15780
    “…The manual identification and segmentation of the cervical spine on MRI makes it a laborious, time-consuming, and error-prone process. …”
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    SeUneter: Channel attentive U-Net for instance segmentation of the cervical spine MRI medical image
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