Structural and immunologic correlates of chemically stabilized HIV-1 envelope glycoproteins

por Schiffner, Torben, Pallesen, Jesper, Russell, Rebecca A., Dodd, Jonathan, de Val, Natalia, LaBranche, Celia C., Montefiori, David, Tomaras, Georgia D., Shen, Xiaoying, Harris, Scarlett L., Moghaddam, Amin E., Kalyuzhniy, Oleksandr, Sanders, Rogier W., McCoy, Laura E., Moore, John P., Ward, Andrew B., Sattentau, Quentin J.
Publicado 2018

Immunogenicity, safety, and efficacy of sequential immunizations with an SIV-based IDLV expressing CH505 Envs

por Blasi, Maria, Negri, Donatella, Saunders, Kevin O., Baker, Erich J., Stadtler, Hannah, LaBranche, Celia, Mildenberg, Benjamin, Morton, Georgeanna, Ciarla, Andrew, Shen, Xiaoying, Wang, Yunfei, Rountree, Wes, Balakumaran, Bala, Santra, Sampa, Haynes, Barton F., Moody, Anthony M., Cara, Andrea, Klotman, Mary E.
Publicado 2020

Priming with DNA Expressing Trimeric HIV V1V2 Alters the Immune Hierarchy Favoring the Development of V2-Specific Antibodies in Rhesus Macaques

por Devasundaram, Santhi, Rosati, Margherita, Valentin, Antonio, Weiss, Svenja, Itri, Vincenza, Trinh, Hung V., Bear, Jenifer, Chowdhury, Bhabadeb, LaBranche, Celia C., Montefiori, David, Ferrari, Guido, Rao, Mangala, Kong, Xiang-Peng, Zolla-Pazner, Susan, Pavlakis, George N., Felber, Barbara K.
Publicado 2020

Antibody responses induced by SHIV infection are more focused than those induced by soluble native HIV-1 envelope trimers in non-human primates

por van Schooten, Jelle, van Haaren, Marlies M., Li, Hui, McCoy, Laura E., Havenar-Daughton, Colin, Cottrell, Christopher A., Burger, Judith A., van der Woude, Patricia, Helgers, Leanne C., Tomris, Ilhan, Labranche, Celia C., Montefiori, David C., Ward, Andrew B., Burton, Dennis R., Moore, John P., Sanders, Rogier W., Crotty, Shane, Shaw, George M., van Gils, Marit J.
Publicado 2021

The Glycan Hole Area of HIV-1 Envelope Trimers Contributes Prominently to the Induction of Autologous Neutralization

por Schorcht, Anna, Cottrell, Christopher A., Pugach, Pavel, Ringe, Rajesh P., Han, Alvin X., Allen, Joel D., van den Kerkhof, Tom L. G. M., Seabright, Gemma E., Schermer, Edith E., Ketas, Thomas J., Burger, Judith A., van Schooten, Jelle, LaBranche, Celia C., Ozorowski, Gabriel, de Val, Natalia, Bader, Daniel L. V., Schuitemaker, Hanneke, Russell, Colin A., Montefiori, David C., van Gils, Marit J., Crispin, Max, Klasse, P. J., Ward, Andrew B., Moore, John P., Sanders, Rogier W.
Publicado 2022

E4orf1 Suppresses E1B-Deleted Adenovirus Vaccine-Induced Immune Responses

por Sangare, Kotou, Helmold Hait, Sabrina, Moore, Madison, Hogge, Christopher, Hoang, Tanya, Rahman, Mohammad Arif, Venzon, David J., LaBranche, Celia, Montefiori, David, Robert-Guroff, Marjorie, Thomas, Michael A.
Publicado 2022

Identification of IOMA-class neutralizing antibodies targeting the CD4-binding site on the HIV-1 envelope glycoprotein

por van Schooten, Jelle, Farokhi, Elinaz, Schorcht, Anna, van den Kerkhof, Tom L. G. M., Gao, Hongmei, van der Woude, Patricia, Burger, Judith A., Meesters, Tim G. Rijkhold, Bijl, Tom, Ghalaiyini, Riham, Turner, Hannah L., Dorning, Jessica, van Schaik, Barbera D. C., van Kampen, Antoine H. C., Labranche, Celia C., Stanfield, Robyn L., Sok, Devin, Montefiori, David C., Burton, Dennis R., Seaman, Michael S., Ozorowski, Gabriel, Wilson, Ian A., Sanders, Rogier W., Ward, Andrew B., van Gils, Marit J.
Publicado 2022

Germline-targeting SOSIP trimer immunization elicits precursor CD4 binding-site targeting broadly neutralizing antibodies in infant macaques

por Nelson, Ashley N., Shen, Xiaoying, Vekatayogi, Sravani, Zhang, Shiyu, Ozorowski, Gabriel, Dennis, Maria, Sewall, Leigh M., Milligan, Emma, Davis, Dominique, Cross, Kaitlyn A., Chen, Yue, van Schooten, Jelle, Eudailey, Joshua, Isaac, John, Memon, Saad, Weinbaum, Carolyn, Stanfield-Oakley, Sherry, Byrd, Alliyah, Chutkan, Suni, Berendam, Stella, Cronin, Kenneth, Yasmeen, Anila, Alam, S. Munir, LaBranche, Celia C., Rogers, Kenneth, Shirreff, Lisa, Cupo, Albert, Derking, Ronald, Villinger, Francois, Klasse, Per Johan, Ferrari, Guido, Williams, Wilton B., Hudgens, Michael G., Ward, Andrew B., Montefiori, David C., Van Rompay, Koen K.A., Wiehe, Kevin, Moore, John P., Sanders, Rogier W., De Paris, Kristina, Permar, Sallie R.
Publicado 2023

Pre-Clinical Development of a Recombinant, Replication-Competent Adenovirus Serotype 4 Vector Vaccine Expressing HIV-1 Envelope 1086 Clade C

por Alexander, Jeff, Mendy, Jason, Vang, Lo, Avanzini, Jenny B., Garduno, Fermin, Manayani, Darly J., Ishioka, Glenn, Farness, Peggy, Ping, Li-Hua, Swanstrom, Ronald, Parks, Robert, Liao, Hua-Xin, Haynes, Barton F., Montefiori, David C., LaBranche, Celia, Smith, Jonathan, Gurwith, Marc, Mayall, Tim
Publicado 2013

Engineering Recombinant Reoviruses To Display gp41 Membrane-Proximal External-Region Epitopes from HIV-1

por Boehme, Karl W., Ikizler, Mine', Iskarpatyoti, Jason A., Wetzel, J. Denise, Willis, Jordan, Crowe, James E., LaBranche, Celia C., Montefiori, David C., Wilson, Gregory J., Dermody, Terence S.
Publicado 2016

Cross-Linking of a CD4-Mimetic Miniprotein with HIV-1 Env gp140 Alters Kinetics and Specificities of Antibody Responses against HIV-1 Env in Macaques

por Shen, Xiaoying, Bogers, Willy M., Yates, Nicole L., Ferrari, Guido, Dey, Antu K., Williams, William T., Jaeger, Frederick H., Wiehe, Kevin, Sawant, Sheetal, Alam, S. Munir, LaBranche, Celia C., Montefiori, David C., Martin, Loic, Srivastava, Indresh, Heeney, Jonathan, Barnett, Susan W., Tomaras, Georgia D.
Publicado 2017

Adeno-associated virus vectored immunoprophylaxis to prevent HIV in healthy adults: a phase 1 randomised controlled trial

por Priddy, Frances H, Lewis, David J M, Gelderblom, Huub C, Hassanin, Hana, Streatfield, Claire, LaBranche, Celia, Hare, Jonathan, Cox, Josephine H, Dally, Len, Bendel, Daryl, Montefiori, David, Sayeed, Eddy, Ackland, Jim, Gilmour, Jill, Schnepp, Bruce C, Wright, J Fraser, Johnson, Philip
Publicado 2019

Bridging Vaccine-Induced HIV-1 Neutralizing and Effector Antibody Responses in Rabbit and Rhesus Macaque Animal Models

por Pollara, Justin, Jones, Dorothy I., Huffman, Tori, Edwards, R. Whitney, Dennis, Maria, Li, Shuk Hang, Jha, Shalini, Goodman, Derrick, Kumar, Amit, LaBranche, Celia C., Montefiori, David C., Fouda, Genevieve G., Hope, Thomas J., Tomaras, Georgia D., Staats, Herman F., Ferrari, Guido, Permar, Sallie R.
Publicado 2019

Neutralizing Antibody Induction by HIV-1 Envelope Glycoprotein SOSIP Trimers on Iron Oxide Nanoparticles May Be Impaired by Mannose Binding Lectin

por Ringe, Rajesh P., Cruz Portillo, Victor M., Dosenovic, Pia, Ketas, Thomas J., Ozorowski, Gabriel, Nogal, Bartek, Perez, Lautaro, LaBranche, Celia C., Lim, Jillian, Francomano, Erik, Wilson, Ian A., Sanders, Rogier W., Ward, Andrew B., Montefiori, David C., Nussenzweig, Michel C., Klasse, P. J., Cupo, Albert, Moore, John P.
Publicado 2020

The Immunological Impact of Adenovirus Early Genes on Vaccine-Induced Responses in Mice and Nonhuman Primates

por Sangare, Kotou, Tuero, Iskra, Rahman, Mohammad Arif, Hoang, Tanya, Miller-Novak, Leia K., Vargas-Inchaustegui, Diego A., Venzon, David J., LaBranche, Celia, Montefiori, David C., Robert-Guroff, Marjorie, Thomas, Michael A.
Publicado 2021

Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies

por Williams, Wilton B., Meyerhoff, R. Ryan, Edwards, R.J., Li, Hui, Manne, Kartik, Nicely, Nathan I., Henderson, Rory, Zhou, Ye, Janowska, Katarzyna, Mansouri, Katayoun, Gobeil, Sophie, Evangelous, Tyler, Hora, Bhavna, Berry, Madison, Abuahmad, A. Yousef, Sprenz, Jordan, Deyton, Margaret, Stalls, Victoria, Kopp, Megan, Hsu, Allen L., Borgnia, Mario J., Stewart-Jones, Guillaume B.E., Lee, Matthew S., Bronkema, Naomi, Moody, M. Anthony, Wiehe, Kevin, Bradley, Todd, Alam, S. Munir, Parks, Robert J., Foulger, Andrew, Oguin, Thomas, Sempowski, Gregory D., Bonsignori, Mattia, LaBranche, Celia C., Montefiori, David C., Seaman, Michael, Santra, Sampa, Perfect, John, Francica, Joseph R., Lynn, Geoffrey M., Aussedat, Baptiste, Walkowicz, William E., Laga, Richard, Kelsoe, Garnett, Saunders, Kevin O., Fera, Daniela, Kwong, Peter D., Seder, Robert A., Bartesaghi, Alberto, Shaw, George M., Acharya, Priyamvada, Haynes, Barton F.
Publicado 2021

Persistent immunogenicity of integrase defective lentiviral vectors delivering membrane-tethered native-like HIV-1 envelope trimers

por Gallinaro, Alessandra, Pirillo, Maria Franca, Aldon, Yoann, Cecchetti, Serena, Michelini, Zuleika, Tinari, Antonella, Borghi, Martina, Canitano, Andrea, McKay, Paul F., Bona, Roberta, Vescio, Maria Fenicia, Grasso, Felicia, Blasi, Maria, Baroncelli, Silvia, Scarlatti, Gabriella, LaBranche, Celia, Montefiori, David, Klotman, Mary E., Sanders, Rogier W., Shattock, Robin J., Negri, Donatella, Cara, Andrea
Publicado 2022

Mucosal B Cells Are Associated with Delayed SIV Acquisition in Vaccinated Female but Not Male Rhesus Macaques Following SIV(mac251) Rectal Challenge

por Tuero, Iskra, Mohanram, Venkatramanan, Musich, Thomas, Miller, Leia, Vargas-Inchaustegui, Diego A., Demberg, Thorsten, Venzon, David, Kalisz, Irene, Kalyanaraman, V. S., Pal, Ranajit, Ferrari, Maria Grazia, LaBranche, Celia, Montefiori, David C., Rao, Mangala, Vaccari, Monica, Franchini, Genoveffa, Barnett, Susan W., Robert-Guroff, Marjorie
Publicado 2015

Reducing V3 Antigenicity and Immunogenicity on Soluble, Native-Like HIV-1 Env SOSIP Trimers

por Ringe, Rajesh P., Ozorowski, Gabriel, Rantalainen, Kimmo, Struwe, Weston B., Matthews, Katie, Torres, Jonathan L., Yasmeen, Anila, Cottrell, Christopher A., Ketas, Thomas J., LaBranche, Celia C., Montefiori, David C., Cupo, Albert, Crispin, Max, Wilson, Ian A., Ward, Andrew B., Sanders, Rogier W., Klasse, P. J., Moore, John P.
Publicado 2017