Copy number architectures define treatment-mediated selection of lethal prostate cancer clones

por Hasan, A. M. Mahedi, Cremaschi, Paolo, Wetterskog, Daniel, Jayaram, Anuradha, Wong, Stephen Q., Williams, Scott, Pasam, Anupama, Trigos, Anna, Trujillo, Blanca, Grist, Emily, Friedrich, Stefanie, Vainauskas, Osvaldas, Parry, Marina, Ismail, Mazlina, Devlies, Wout, Wingate, Anna, Linch, Mark, Naceur-Lombardelli, Cristina, Swanton, Charles, Jamal-Hanjani, Mariam, Lise, Stefano, Sandhu, Shahneen, Attard, Gerhardt
Publicado 2023

Signal peptide mimicry primes Sec61 for client-selective inhibition

por Rehan, Shahid, Tranter, Dale, Sharp, Phillip P., Craven, Gregory B., Lowe, Eric, Anderl, Janet L., Muchamuel, Tony, Abrishami, Vahid, Kuivanen, Suvi, Wenzell, Nicole A., Jennings, Andy, Kalyanaraman, Chakrapani, Strandin, Tomas, Javanainen, Matti, Vapalahti, Olli, Jacobson, Matthew P., McMinn, Dustin, Kirk, Christopher J., Huiskonen, Juha T., Taunton, Jack, Paavilainen, Ville O.
Publicado 2023

Decoding biological age from face photographs using deep learning

por Zalay, Osbert, Bontempi, Dennis, Bitterman, Danielle S, Birkbak, Nicolai, Shyr, Derek, Haugg, Fridolin, Qian, Jack M, Roberts, Hannah, Perni, Subha, Prudente, Vasco, Pai, Suraj, Dekker, Andre, Haibe-Kains, Benjamin, Guthier, Christian, Balboni, Tracy, Warren, Laura, Krishan, Monica, Kann, Benjamin H, Swanton, Charles, Ruysscher, Dirk De, Mak, Raymond H, Aerts, Hugo JWL
Publicado 2023

COP27 Climate Change Conference: Urgent action needed for Africa and the world: Wealthy nations must step up support for Africa and vulnerable countries in addressing past, present...

por Atwoli, Lukoye, Erhabor, Gregory E, Gbakima, Aiah A, Haileamlak, Abraham, Ntumba, Jean-Marie Kayembe, Kigera, James, Laybourn-Langton, Laurie, Mash, Bob, Muhia, Joy, Mulaudzi, Fhumulani Mavis, Ofori-Adjei, David, Okonofua, Friday, Rashidian, Arash, El-Adawy, Maha, Sidibé, Siaka, Snouber, Abdelmadjid, Tumwine, James, Yassien, Mohammad Sahar, Yonga, Paul, Zakhama, Lilia, Zielinski, Chris
Publicado 2022

Predictive biomarker discovery through the parallel integration of clinical trial and functional genomics datasets

por Swanton, Charles, Larkin, James M, Gerlinger, Marco, Eklund, Aron C, Howell, Michael, Stamp, Gordon, Downward, Julian, Gore, Martin, Futreal, P Andrew, Escudier, Bernard, Andre, Fabrice, Albiges, Laurence, Beuselinck, Benoit, Oudard, Stephane, Hoffmann, Jens, Gyorffy, Balázs, Torrance, Chris J, Boehme, Karen A, Volkmer, Hansjuergen, Toschi, Luisella, Nicke, Barbara, Beck, Marlene, Szallasi, Zoltan
Publicado 2010

Chemical–biological characterization of a cruzain inhibitor reveals a second target and a mammalian off-target

por Choy, Jonathan W, Bryant, Clifford, Calvet, Claudia M, Doyle, Patricia S, Gunatilleke, Shamila S, Leung, Siegfried S F, Ang, Kenny K H, Chen, Steven, Gut, Jiri, Oses-Prieto, Juan A, Johnston, Jonathan B, Arkin, Michelle R, Burlingame, Alma L, Taunton, Jack, Jacobson, Matthew P, McKerrow, James M, Podust, Larissa M, Renslo, Adam R
Publicado 2013

Evaluating the Accuracy of Molecular Diagnostic Testing for Canine Visceral Leishmaniasis Using Latent Class Analysis

por Solcà, Manuela da Silva, Bastos, Leila Andrade, Guedes, Carlos Eduardo Sampaio, Bordoni, Marcelo, Borja, Lairton Souza, Larangeira, Daniela Farias, da Silva Estrela Tuy, Pétala Gardênia, Amorim, Leila Denise Alves Ferreira, Nascimento, Eliane Gomes, de Sá Oliveira, Geraldo Gileno, dos-Santos, Washington Luis Conrado, Fraga, Deborah Bittencourt Mothé, Veras, Patrícia Sampaio Tavares
Publicado 2014

Replication stress links structural and numerical cancer chromosomal instability

por Burrell, Rebecca A., McClelland, Sarah E., Endesfelder, David, Groth, Petra, Weller, Marie-Christine, Shaikh, Nadeem, Domingo, Enric, Kanu, Nnennaya, Dewhurst, Sally M., Gronroos, Eva, Chew, Su Kit, Rowan, Andrew J., Schenk, Arne, Sheffer, Michal, Howell, Michael, Kschischo, Maik, Behrens, Axel, Helleday, Thomas, Bartek, Jiri, Tomlinson, Ian P., Swanton, Charles
Publicado 2013

BCL9L Dysfunction Impairs Caspase-2 Expression Permitting Aneuploidy Tolerance in Colorectal Cancer

por López-García, Carlos, Sansregret, Laurent, Domingo, Enric, McGranahan, Nicholas, Hobor, Sebastijan, Birkbak, Nicolai Juul, Horswell, Stuart, Grönroos, Eva, Favero, Francesco, Rowan, Andrew J., Matthews, Nicholas, Begum, Sharmin, Phillimore, Benjamin, Burrell, Rebecca, Oukrif, Dahmane, Spencer-Dene, Bradley, Kovac, Michal, Stamp, Gordon, Stewart, Aengus, Danielsen, Havard, Novelli, Marco, Tomlinson, Ian, Swanton, Charles
Publicado 2017

Precision medicine for suicidality: from universality to subtypes and personalization

por Niculescu, A B, Le-Niculescu, H, Levey, D F, Phalen, P L, Dainton, H L, Roseberry, K, Niculescu, E M, Niezer, J O, Williams, A, Graham, D L, Jones, T J, Venugopal, V, Ballew, A, Yard, M, Gelbart, T, Kurian, S M, Shekhar, A, Schork, N J, Sandusky, G E, Salomon, D R
Publicado 2017

Notes from the Field: A Multipartner Response to Prevent a Binational Rabies Outbreak — Anse-à-Pitre, Haiti, 2019

por Adrien, Joane, Georges, Yvenel, Augustin, Pierre D., Monroe, Benjamin, Gibson, Andrew D., Fenelon, Natael, Fleurinord, Ludder, Crowdis, Kelly, Mandra, Anna, Joseph, Haim C., Etheart, Melissa D., Wallace, Ryan M., Blanton, Jesse, Cleaton, Julie, Condori, Rene Edgar, Petersen, Brett, Ross, Yasmeen, Moran, David, Tataryn, Joanne, Gamble, Luke, Lohr, Fred, King, Alasdair
Publicado 2019

Effect of delays in the 2-week-wait cancer referral pathway during the COVID-19 pandemic on cancer survival in the UK: a modelling study

por Sud, Amit, Torr, Bethany, Jones, Michael E, Broggio, John, Scott, Stephen, Loveday, Chey, Garrett, Alice, Gronthoud, Firza, Nicol, David L, Jhanji, Shaman, Boyce, Stephen A, Williams, Matthew, Riboli, Elio, Muller, David C, Kipps, Emma, Larkin, James, Navani, Neal, Swanton, Charles, Lyratzopoulos, Georgios, McFerran, Ethna, Lawler, Mark, Houlston, Richard, Turnbull, Clare
Publicado 2020

Collateral damage: the impact on outcomes from cancer surgery of the COVID-19 pandemic

por Sud, A., Jones, M.E., Broggio, J., Loveday, C., Torr, B., Garrett, A., Nicol, D.L., Jhanji, S., Boyce, S.A., Gronthoud, F., Ward, P., Handy, J.M., Yousaf, N., Larkin, J., Suh, Y-E., Scott, S., Pharoah, P.D.P., Swanton, C., Abbosh, C., Williams, M., Lyratzopoulos, G., Houlston, R., Turnbull, C.
Publicado 2020

Clinical outcomes of COVID-19 in long-term care facilities for people with epilepsy

por Balestrini, Simona, Koepp, Matthias J., Gandhi, Sonia, Rickman, Hannah M., Shin, Gee Yen, Houlihan, Catherine F., Anders-Cannon, Jonny, Silvennoinen, Katri, Xiao, Fenglai, Zagaglia, Sara, Hudgell, Kirsty, Ziomek, Mariusz, Haimes, Paul, Sampson, Adam, Parker, Annie, Helen Cross, J., Pardington, Rosemarie, Nastouli, Eleni, Swanton, Charles, Sander, Josemir W., Sisodiya, Sanjay M.
Publicado 2021

AZD1222-induced neutralising antibody activity against SARS-CoV-2 Delta VOC

por Wall, Emma C, Wu, Mary, Harvey, Ruth, Kelly, Gavin, Warchal, Scott, Sawyer, Chelsea, Daniels, Rodney, Adams, Lorin, Hobson, Philip, Hatipoglu, Emine, Ngai, Yenting, Hussain, Saira, Ambrose, Karen, Hindmarsh, Steve, Beale, Rupert, Riddell, Andrew, Gamblin, Steve, Howell, Michael, Kassiotis, George, Libri, Vincenzo, Williams, Bryan, Swanton, Charles, Gandhi, Sonia, Bauer, David LV
Publicado 2021

Bronchial Thermoplasty Global Registry (BTGR): 2-year results

por Torrego, Alfons, Herth, Felix J, Munoz-Fernandez, Ana M, Puente, Luis, Facciolongo, Nicola, Bicknell, Stephen, Novali, Mauro, Gasparini, Stefano, Bonifazi, Martina, Dheda, Keertan, Andreo, Felipe, Votruba, Praha, Langton, David, Flandes, Javier, Fielding, David, Bonta, Peter I, Skowasch, Dirk, Schulz, Christian, Darwiche, Kaid, McMullen, Edmund, Grubb, G. Mark, Niven, Robert
Publicado 2021

Paracrine signal emanating from stressed cardiomyocytes aggravates inflammatory microenvironment in diabetic cardiomyopathy

por Kaur, Namrita, Ruiz-Velasco, Andrea, Raja, Rida, Howell, Gareth, Miller, Jessica M., Abouleisa, Riham R.E., Ou, Qinghui, Mace, Kimberly, Hille, Susanne S., Frey, Norbert, Binder, Pablo, Smith, Craig P., Fachim, Helene, Soran, Handrean, Swanton, Eileithyia, Mohamed, Tamer M.A., Müller, Oliver J., Wang, Xin, Chernoff, Jonathan, Cartwright, Elizabeth J., Liu, Wei
Publicado 2022

Severe Acute Respiratory Syndrome Coronavirus 2 Anti-Spike Antibody Levels Following Second Dose of ChAdOx1 nCov-19 or BNT162b2 Vaccine in Residents of Long-term Care Facilities in...

por Stirrup, Oliver, Krutikov, Maria, Tut, Gokhan, Palmer, Tom, Bone, David, Bruton, Rachel, Fuller, Chris, Azmi, Borscha, Lancaster, Tara, Sylla, Panagiota, Kaur, Nayandeep, Spalkova, Eliska, Bentley, Christopher, Amin, Umayr, Jadir, Azar, Hulme, Samuel, Giddings, Rebecca, Nacer-Laidi, Hadjer, Baynton, Verity, Irwin-Singer, Aidan, Hayward, Andrew, Moss, Paul, Copas, Andrew, Shallcross, Laura
Publicado 2022

Antibody and cellular immune responses following dual COVID-19 vaccination within infection-naive residents of long-term care facilities: an observational cohort study

por Tut, Gokhan, Lancaster, Tara, Sylla, Panagiota, Butler, Megan S, Kaur, Nayandeep, Spalkova, Eliska, Bentley, Christopher, Amin, Umayr, Jadir, Azar, Hulme, Samuel, Ayodele, Morenike, Bone, David, Tut, Elif, Bruton, Rachel, Krutikov, Maria, Giddings, Rebecca, Shrotri, Madhumita, Azmi, Borscha, Fuller, Christopher, Baynton, Verity, Irwin-Singer, Aidan, Hayward, Andrew, Copas, Andrew, Shallcross, Laura, Moss, Paul
Publicado 2022

COP27 climate change conference: urgent action needed for Africa and the world

por Atwoli, Lukoye, Erhabor, Gregory E, Gbakima, Aiah A, Haileamlak, Abraham, Ntumba, Jean-Marie Kayembe, Kigera, James, Laybourn-Langton, Laurie, Mash, Bob, Muhia, Joy, Mulaudzi, Fhumulani Mavis, Ofori-Adjei, David, Okonofua, Friday, Rashidian, Arash, El-Adawy, Maha, Sidibé, Siaka, Snouber, Abdelmadjid, Tumwine, James, Yassien, Mohammad Sahar, Yonga, Paul, Zakhama, Lilia, Zielinski, Chris
Publicado 2022