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  1. 501
    por Ravazzini, Laura
    Publicado 2018
    “…Fuelled by federal stimuli of 440 million Swiss francs, the staggered expansion of childcare in many cantons allows the evaluation of this family policy on female labour supply. …”
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    Childcare and maternal part-time employment: a natural experiment using Swiss cantons
  2. 502
    por Page, Antony P.
    Publicado 2018
    “…Control of these parasites is almost exclusively dependent on a small group of anthelmintic drugs, the most important of which belong to the macrocyclic lactone class. The extensive use of these drugs to control the ubiquitous trichostrongylid parasites of grazing livestock has resulted in the emergence of both single and multi-drug resistance. …”
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    The sensory amphidial structures of Caenorhabditis elegans are involved in macrocyclic lactone uptake and anthelmintic resistance
  3. 503
    “…The Asteraceae, one of the largest families among angiosperms, is chemically characterised by the production of sesquiterpene lactones (SLs). A total of 1,111 SLs, which were extracted from 658 species, 161 genera, 63 subtribes and 15 tribes of Asteraceae, were represented and registered in two dimensions in the SISTEMATX, an in-house software system, and were associated with their botanical sources. …”
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    Self-Organizing Maps of Molecular Descriptors for Sesquiterpene Lactones and Their Application to the Chemotaxonomy of the Asteraceae Family
  4. 504
    por Yang, Xiao-Long, Li, Zhuang-Zhuang
    Publicado 2013
    “…(−)-(4S, 8S)-Foedanolide (1a) and (+)-(4R, 8R)-foedanolide (1b), a pair of new spiro-γ-lactone enantiomers, were isolated from the fermentation broth of the plant endophytic fungus Pestalotiopsis foedan by HPLC using a chiral column, achieving over 7% ee. …”
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    New Spiral γ-Lactone Enantiomers from the Plant Endophytic Fungus Pestalotiopsis foedan
  5. 505
    “…In the present work, a quantitative (1)H Nuclear Magnetic Resonance (qHNMR) was established for purity assessment of six aryltetralin lactone lignans. The validation of the method was carried out, including specificity, selectivity, linearity, accuracy, precision, and robustness. …”
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    Purity Assessment of Aryltetralin Lactone Lignans by Quantitative (1)H Nuclear Magnetic Resonance
  6. 506
    “…Here we demonstrate efficient total biosynthetic and biocatalytic platforms that use a pair of fungal OMTs with orthogonal regiospecificity to produce unnatural O-methylated benzenediol lactone polyketides. We show that rational, structure-guided active-site cavity engineering can reprogram the regioselectivity of these enzymes. …”
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    Rational Reprogramming of O-Methylation Regioselectivity for Combinatorial Biosynthetic Tailoring of Benzenediol Lactone Scaffolds
  7. 507
    “…We found a strong relationship between bacterial genetic variation and pyomyositis, with estimated heritability 63.8% (95% CI 49.2–78.4%). The presence of the Panton–Valentine leucocidin (PVL) locus increased the odds of pyomyositis 130-fold (p=10(-17.9)). …”
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    Panton–Valentine leucocidin is the key determinant of Staphylococcus aureus pyomyositis in a bacterial GWAS
  8. 508
    “…In the presented work, five bio-based and bio-degradable cyclic esters, i.e. lactones, have been investigated as possible phase change materials for applications in latent heat storage systems. …”
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    Investigation of Lactones as Innovative Bio-Sourced Phase Change Materials for Latent Heat Storage
  9. 509
    por Marzec, Anna, Szadkowski, Bolesław
    Publicado 2019
    “…In this study, we produced a new organic-inorganic hybrid pigment based on a natural chromophore. Lawsone was selected as the active organic compound and incorporated into aluminum-magnesium hydroxycarbonate (LH). …”
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    Improved Aging Stability of Ethylene-Norbornene Composites Filled with Lawsone-Based Hybrid Pigment
  10. 510
    “…METHODS: We included all first primary breast adenocarcinoma diagnosed between 2006 and 2014 in women aged 50–69 years resident in the canton of Fribourg. We considered only breast cancer discovered by mammography screening. …”
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    Comparison between opportunistic and organised breast cancer mammography screening in the Swiss canton of Fribourg
  11. 511
    “…In addition, the synthesis of fatty γ-lactones, corresponding to 4-hydroxy fatty acids, was also explored.…”
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    Enantioselective Organocatalysis-Based Synthesis of 3-Hydroxy Fatty Acids and Fatty γ-Lactones
  12. 512
    “…[Image: see text] The conversion of troponyl alkylglycinate acid/ester/amide derivatives (Trag acid/ester/amide) into cationic troponyl lactones (CTLs) in the presence of trifluoroacetic acid and their amidation with amines is described. …”
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    Direct/Reversible Amidation of Troponyl Alkylglycinates via Cationic Troponyl Lactones and Mechanistic Insights
  13. 513
    “…[Image: see text] This study aims to develop an intermolecular lactonization reaction of alkenes with carbonyls mediated by visible light and molecular iodine. …”
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    trans-Diastereoselective Syntheses of γ-Lactones by Visible Light-Iodine-Mediated Carboesterification of Alkenes
  14. 514
    “…In the course of our investigations on the antitrypanosomal potential of sesquiterpene lactones (STL), we have recently reported on the exceptionally strong activity of 4,15-iso-Atriplicolide tiglate, which demonstrated an IC(50) value of 15 nM against Trypanosoma brucei rhodesiense, the etiologic agent responsible for East African human trypanosomiasis (HAT). …”
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    Natural Sesquiterpene Lactones of the 4,15-iso-Atriplicolide Type are Inhibitors of Trypanothione Reductase
  15. 515
    “…Production of the Panton-Valentine leukocidin (PVL) by Staphylococcus aureus is mediated via the genes lukS-PV and lukF-PV which are carried on bacteriophage ϕSa2. …”
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    Diversity of bacteriophages encoding Panton-Valentine leukocidin in temporally and geographically related Staphylococcus aureus
  16. 516
    “…The demand for natural lactone gamma-decalactone (GDL) has increased in the fields of food and cosmetic products. …”
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    Bacterial Cellulose-Alginate Composite Beads as Yarrowia lipolytica Cell Carriers for Lactone Production
  17. 517
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    Detection of viruses by electron microscopy in fecal samples from patients with gastroenteritis in the canton of Vaud
  18. 518
    “…MAIN CONCLUSION: Tissue-specific occurrence and formation of endogenous sesquiterpene lactones has been assessed and suggests physiological function as antagonists of auxin-induced plant growth in sunflower. …”
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    Spatial and developmental synthesis of endogenous sesquiterpene lactones supports function in growth regulation of sunflower
  19. 519
    “…Acyl homoserine lactones (AHLs), the quorum sensing (QS) signals produced by Gram-negative bacteria, are currently considered to play a minor role in the development of oral biofilm since their production by oral pathogens has not been ascertained thus far. …”
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    Acyl homoserine lactone-mediated quorum sensing in the oral cavity: a paradigm revisited
  20. 520
    “…The HPLC fractionation of the CH(2)Cl(2) phase of the MeOH extract from the leaves of C. pinnatifida led to the isolation of two related sesquiterpene lactones (STLs): calein C (1) and calealactone B (2). …”
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    Sesquiterpene Lactones from Calea pinnatifida: Absolute Configuration and Structural Requirements for Antitumor Activity
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