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  1. 581
    “…A 56-year-old gentleman presented with acute delirium, fever and rigor. Panton-Valentine leukocidin (PVL)-positive Staphylococcus aureus (S. aureus) was isolated in the blood culture and the PR interval was prolonged on the electrocardiogram (ECG). …”
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    Acquired Ventricular Septal Defect in Panton-Valentine Leukocidin-Positive Staphylococcus aureus Infective Endocarditis
  2. 582
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    Social and Preventive Factors That Explain Oral Health among Pregnant Women in the Canton of Cuenca, Ecuador
  3. 583
    “…The method substantially simplifies the synthesis of important bicyclic lactones that are important features of natural products as well as pharmacoactive molecules. …”
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    Access to unsaturated bicyclic lactones by overriding conventional C(sp(3))–H site selectivity
  4. 584
    “…BACKGROUND: In Pseudomonas putida and Pseduomonas aeruginosa, the similar PpuR/RsaL/PpuI and LasR/RsaL/LasI acyl homoserine lactones (AHLs) quorum sensing (QS) systems have been shown to be under considerable regulation by other global regulators. …”
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    The Pseudomonas putida Lon protease is involved in N-acyl homoserine lactone quorum sensing regulation
  5. 585
    “…Strains from children and HCW were indistinguishable. All carried the Panton-Valentine leukocidine (PVL), the staphylococcal enterotoxin B gene, the gene complex for staphylococcal-cassette-chromosome mec type V, and were sequence type 59. …”
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    An Outbreak of Severe Infections with Community-Acquired MRSA Carrying the Panton-Valentine Leukocidin Following Vaccination
  6. 586
    “…The role of the pore-forming Staphylococcus aureus toxin Panton-Valentine leukocidin (PVL) in severe necrotizing diseases is debated due to conflicting data from epidemiological studies of community-associated methicillin-resistant S. aureus (CA-MRSA) infections and various murine disease-models. …”
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    Staphylococcus aureus Panton-Valentine Leukocidin Is a Very Potent Cytotoxic Factor for Human Neutrophils
  7. 587
    “…X-ray crystallographic analysis has established that the major product from the protection of d-glucoronolactone with benzaldehyde is (1S)-1,2-O-benzyl­idene-α-d-glucurono-6,3-lactone, C(13)H(12)O(6), rather than the R epimer. …”
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    (1S)-1,2-O-Benzyl­idene-α-d-glucurono-6,3-lactone
  8. 588
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    Vasorelaxant effect of diterpenoid lactones from Andrographis paniculata chloroform extract on rat aortic rings
  9. 589
    “…Atorvastatin δ-lactone, a major, pharmacologically inactive metabolite, has been associated with toxicity. …”
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    Paraoxonase (PON1 and PON3) Polymorphisms: Impact on Liver Expression and Atorvastatin-Lactone Hydrolysis
  10. 590
    “…PURPOSE: To explore the needs and expectations of diabetic patients and healthcare professionals in the canton of Vaud. CONTEXT: Development and implementation of a diabetes cantonal program. …”
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    Experiences and needs of diabetic patients and healthcare professionals: a qualitative study in the canton of Vaud (Switzerland)
  11. 591
    “…Bacteria communicate by producing quorum sensing molecules called autoinducers, which include autoinducer-1, an N-hexanoyl homoserine lactone (AHL), and autoinducer-2. Bacteria present in the human oral cavity have been shown to produce autoinducer-2, but not AHL. …”
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    N-Acyl Homoserine Lactone Production by Klebsiella pneumoniae Isolated from Human Tongue Surface
  12. 592
    “…BACKGROUND: Invasive community-onset staphylococcal disease has emerged worldwide associated with Panton-Valentine leucocidin (PVL) toxin. Whether PVL is pathogenic or an epidemiological marker is unclear. …”
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    The role of the Panton-Valentine leucocidin toxin in staphylococcal disease: a systematic review and meta-analysis
  13. 593
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    Correction: Transcriptome Analysis of Acyl-Homoserine Lactone-Based Quorum Sensing Regulation in Yersinia pestis
  14. 594
    “…[Image: see text] Flavaglines are a class of natural products with potent insecticidal and anticancer activities. β-Lactones are a privileged structural motif found in both therapeutic agents and chemical probes. …”
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    Remodeling Natural Products: Chemistry and Serine Hydrolase Activity of a Rocaglate-Derived β-Lactone
  15. 595
    “…The proposed HS-SPME-GC method is an appropriate technique for the quantitative analysis of γ-butyrolactone, γ-hexalactone, trans-whiskey lactone, γ-octalactone, cis-whiskey lactone, γ-nonalactone, γ-decalactone, δ-decalactone, and γ-undecalactone in wines. …”
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    Determination of Lactones in Wines by Headspace Solid-Phase Microextraction and Gas Chromatography Coupled with Mass Spectrometry
  16. 596
    “…These secondary metabolites belong to the 12-membered resorcylic acid lactone (RAL(12)) subclass of the benzenediol lactone (BDL) family. …”
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    Insights into the Biosynthesis of 12-Membered Resorcylic Acid Lactones from Heterologous Production in Saccharomyces cerevisiae
  17. 597
    “…CONCLUSION: Staphyloccocus aureus producing Panton-Valentine leukocidin are most commonly responsible for skin and soft tissue infections. …”
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    Prostatic abscesses and severe sepsis due to methicillin-susceptible Staphylococcus aureusproducing Panton-Valentine leukocidin
  18. 598
    “…[Image: see text] The chemo- and regioselectivity and functional group compatibility in gold and palladium cooperatively catalyzed cross-coupling reactions were determined in the synthesis of lactones; the selectivity in the gold and palladium dual-metal catalysis system was distinct from that available for the same class of substrates in systems with only gold catalysis or only palladium catalysis rather than dual catalysis. …”
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    Selectivity, Compatibility, Downstream Functionalization, and Silver Effect in the Gold and Palladium Dual-Catalytic Synthesis of Lactones
  19. 599
    “…Novel N-α-haloacylated homoserine lactones, in which a halogen atom was introduced at the α-position of the carbonyl function of the N-acyl chain, have been studied as quorum sensing (QS) modulators and compared with a library of natural N-acylated homoserine lactones (AHLs). …”
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    Synthesis and biological evaluation of novel N-α-haloacylated homoserine lactones as quorum sensing modulators
  20. 600
    “…MATERIAL AND METHODS: We retrospectively analyzed the epidemiological characteristics of meningococcal meningitis in the area of Zenica-Doboj Canton in the five-year period from 2008 to 2012th. …”
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    Epidemiological Characteristics of Meningococcal Meningitis in the Area of Zenica-Doboj Canton in Period from 2008 to 2012
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