“…In this study, a novel quenching strain of Pseudomonas multiresinivorans QL-9a was isolated and characterized, and it showed excellent degradation ability against AHLs, degrading 98.20% of N-(-3-oxohexanoyl)-L-homoserine lactone (OHHL) within 48 h. Based on the results of the gas chromatography–mass spectrometer (GC–MS) analysis, a possible pathway was proposed to decompose OHHL into fatty acids and homoserine lactone, in which AHL acylase was involved. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…METHODOLOGY/PRINCIPAL FINDINGS: Here, we describe the substrate specificity of SisLac, providing extensive kinetic studies performed with various phosphotriesters, esters, N-acyl-homoserine lactones (AHLs) and other lactones as substrates. Moreover, we solved the X-ray structure of SisLac and structural comparisons with the closely related SsoPox structure highlighted differences in the surface salt bridge network and the dimerization interface. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The dihedral angle between the pyrimidine moiety and the lactone ring system is 29.43 (7)°.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Patients were usually coming from the Tuzla Canton Federation of Bosnia and Herzegovina (28 patients). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The new compound, 4, containing a β-lactone ring, exhibited moderate inhibitory activity against P. theae, with an MIC of 50 μg/disc. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Gap values have evidenced that squamocin is most reactive in methanol while that its large aliphatic chain produces an increases the reactivity of this γ-lactone, as compared with ascorbic acid lactone. Reasonable concordances among the predicted UV–visible and IR, Raman spectra with the corresponding experimental ones were found.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Clusters containing such a pair of PKS genes have been identified in the biosynthesis of resorcylic acid lactones or dihydroxyphenylacetic acid lactones. AdPKS7 and AdPKS8 gene expression patterns correlated with aldaulactone production in different experimental conditions. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Though total volatiles declined during extended cold storage, CA accumulated higher content of volatile esters and lactones than control at 28S3. A total of 14 volatiles were positively correlated with consumer acceptability, mainly including three C6 compounds, three esters and four lactones derived from the fatty acid lipoxygenase (LOX) pathway. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Linton M. Traub and Frances M. Brodsky discuss the life and achievements of Ernst Ungewickell, who passed away on August 19th.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…After ivermectin and abamectin treatment, no relevant statistically significant differences in plasma levels of clorsulon were reported between the experimental groups since there were no differences in the area under the plasma concentration-curve (AUC) between clorsulon treatment alone and coadministration with macrocyclic lactones. With regard to milk, total amount of clorsulon, as percentage of dose excreted, did not show statistically significant differences when macrocyclic lactones were coadministered. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Important differences in prescription prevalence across cantons were observed, suggesting potential overuse. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Rich theme that Geneva, the town and the Canton, partners of the demonstration, has chosen to evoke it. (1 page)…”
Enlace del recurso

“…CERN has now been mandated by DAEL (the representative of the Canton of Geneva) to enter into a contract with the firm selected by DAEL. …”
Enlace del recurso

“…So far, only some antimycotics, killer toxins and Massoia lactone haven been found to be able to actively control and kill its growth. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The mol­ecule has two fused rings consisting of a tetra­hydro-2H-pyran and a lactone ring, with the benzene ring and the acetyl group attached to the tetra­hydro-2H-pyran ring. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Ten new briarane diterpenoids, briaviolides A–J (1–10), together with six known briaranes, solenolides A and D, excavatolide A, briaexcavatolide I, 4β-acetoxy-9-deacetystylatulide lactone and 9-deacetylstylatulide lactone, were isolated from the Taiwanese soft coral, Briareum violacea. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Numerous bacteria coordinate gene expression in response to small signalling molecules in many cases known as acylhomoserine lactones (AHLs), which accumulate as a function of cell density in a process known as quorum sensing. …”
Enlace del recurso
Enlace del recurso

“…The C-ring was synthesized via an oxiranyl anion coupling and a 6-endo cyclization, and the D-ring was forged by means of an oxidative lactonization and subsequent palladium-catalyzed functionalization of the lactone ring. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The concise building of the spiroketal core of acortatarin-type alkaloids as potential therapeutic agents in diabetic nephropathy was established in four steps, through a tandem N-alkylation/hemiacetalization between pyrrole units and the corresponding halo alcohols generated by convenient halomethylation of chiral lactones from natural aldoses. The Acortatarin alkaloids exhibit a promising perspective against diabetic nephropathy and other ROS-linked diseases. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The effects of patient characteristics and health conditions on visiting hospitals outside the residential canton were examined using complete, nationwide, inpatient health records for the years 2010 and 2011. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso