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  1. 6101
    “…By comparing the recorded experimental data, a remarkable activity can be attributed to few of the tested lactones.…”
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    Synthesis of Benzofuran-2-One Derivatives and Evaluation of Their Antioxidant Capacity by Comparing DPPH Assay and Cyclic Voltammetry
  2. 6102
    “…Guaianolides are an important class of sesquiterpene lactones with unique biological and pharmaceutical properties. …”
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    Kauniolide synthase is a P450 with unusual hydroxylation and cyclization-elimination activity
  3. 6103
    “…While treatment with conc. sulfuric acid led to a loss of the carboxanilide residue (accompanied by an expectable lactonization/dehydration process in the side chain), treatment with conc. aqueous hydrochloric acid gave a complex, bridged molecule under C–C-bond formation of the lactone moiety with the pyrrole, migration of the isopropyl group and loss of the carboxanilide residue. …”
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    Characterization of two new degradation products of atorvastatin calcium formed upon treatment with strong acids
  4. 6104
    “…Mexico is the center of origin of the species popularly known as toronjil or lemon balm (Agastache mexicana Linton & Epling). Two subspecies have been identified and are commonly called purple or red (Agastache mexicana Linton & Epling subspecies. mexicana) and white (Agastache mexicana subspecies xolocotziana Bye, E.L. …”
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    A Systematic Approach to Agastache mexicana Research: Biology, Agronomy, Phytochemistry, and Bioactivity
  5. 6105
    “…Fragment‐sized α‐methylene‐sesquiterpene lactones, whose scaffolds can formally be viewed as related to each other or are obtained by ring distortion, were combined with alkaloid‐derived pyrrolidine fragments by means of highly selective stereocomplementary 1,3‐dipolar cycloaddition reactions. …”
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    Combination of Pseudo‐Natural Product Design and Formal Natural Product Ring Distortion Yields Stereochemically and Biologically Diverse Pseudo‐Sesquiterpenoid Alkaloids
  6. 6106
    “…An older gentleman endured extensive perineal trauma after being trapped underneath an industrial-sized lawnmower, and a young adolescent was bitten by an English bulldog and suffered amputation of the glans of his penis. …”
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    Unusual Mechanisms of Penile Amputation
  7. 6107
    por Brice, Maximilien
    Publicado 2014
    “…remise des médailles lors du Scool 2014 - championnat d'orientation inter classe 6p et 8p du canton de Genève…”
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    60 ans anniversaire - activité
  8. 6108
    “…Alternatively, an unspecific L-gulono-1,4-lactone lactonase (smp30) from the animal L-ascorbic acid pathway was introduced in the fungal strain instead of the plant L-galactono-1,4-lactone lactonase. …”
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    Metabolic engineering of the fungal D-galacturonate pathway for L-ascorbic acid production
  9. 6109
    “…BACKGROUND: The existence nematodes of veterinary importance such as Haemonchus contortus resistant to anthelmintic drugs, including the macrocyclic lactones, has become a major concern in animal health. …”
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    Characterisation of P-glycoprotein-9.1 in Haemonchus contortus
  10. 6110
    “…Direct quantification of N-octanoyl-homoserine lactone (C(8)-HSL), N-3-hydroxy-decanoyl-homoserine lactone (3OHC(10)-HSL), and N-3-hydroxy-octanoyl-homoserine lactone (3OHC(8)-HSL), the primary AHLs produced by this bacterium, was performed by liquid chromatography coupled to tandem mass spectrometry (LC-MS/MS) in the wild-type strain and in QS deletion mutants. …”
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    The Complex Quorum Sensing Circuitry of Burkholderia thailandensis Is Both Hierarchically and Homeostatically Organized
  11. 6111
    “…This association is particularly prominent in cantons located along the North and South Pacific Coast, as well as in the Central cantons of the country. …”
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    Common patterns between dengue cases, climate, and local environmental variables in Costa Rica: A wavelet approach
  12. 6112
    “…PAK-200S was effective in restoring the cellular lactone concentrations of topotecan in resistant MCF-7/adr cells to levels comparable to those obtained in parental cells. …”
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    Reversal of MDR1-associated resistance to topotecan by PAK-200S, a new dihydropyridine analogue, in human cancer cell lines
  13. 6113
    por Busato, André, von Below, Georg
    Publicado 2010
    “…DRG-based hospital reimbursement is not simultaneously realized in all Swiss cantons and several cantons already implemented DRG-based financing irrespective of the national agenda, a setting that provides an opportunity to compare the situation in different cantons. …”
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    The implementation of DRG-based hospital reimbursement in Switzerland: A population-based perspective
  14. 6114
    “…N-acyl-homoserine lactonases and N-acyl-homoserine-lactone acylases). Only little is known on quorum quenching mechanisms of oxidoreductases (EC 1). …”
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    A Novel Metagenomic Short-Chain Dehydrogenase/Reductase Attenuates Pseudomonas aeruginosa Biofilm Formation and Virulence on Caenorhabditis elegans
  15. 6115
    “…In addition, octanoyl-homoserine lactone (C(8)-HSL), a quorum sensing molecule, was identified by mass spectrometry analysis in bacterial isolates referred to as LCV CTH, LCV VIT, SCV TOM, SCV CTH, 1 and 3, and the presence of other AHL's with higher masses; decanoyl-homoserine lactone (C(10)-HSL) and dodecanoyl-homoserine lactone (C(12)-HSL) were also found in all tested strain in this study. …”
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    The Effect of Environmental Conditions on Biofilm Formation of Burkholderia pseudomallei Clinical Isolates
  16. 6116
    “…The anti-cancer activity of parthenolide (PTL) isolated from Tanacetum parthenium, has been attributed to the presence of α-methylene-γ-lactone skeleton. In the present study we aimed to investigate the anti-cancer potential of a new synthetic compound, 3-isopropyl-2-methyl-4-methyleneisoxazolidin-5-one (MZ-6), with the same as in PTL α-methylene-γ-lactone motif, on two breast cancer cell lines, MCF-7 and MDA-MB-231. …”
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    Apoptosis-mediated cytotoxic effects of parthenolide and the new synthetic analog MZ-6 on two breast cancer cell lines
  17. 6117
    por Obradovic, Zarema, Obradovic, Amina
    Publicado 2013
    “…MATERIALS AND METHODS: We used protocol books of the Travel Clinic in Public Health Institute of Sarajevo Canton and the data from individual forms of travellers. …”
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    Characteristics of Travellers from Bosnia and Herzegovina to Africa
  18. 6118
    “…The highly active deterrents—dihydro-β-damascol, β-damascone acetate, δ-bromo-γ-lactone, and unsaturated γ-lactone—affected pre-phloem and phloem aphid probing activities. …”
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    Systemic deterrence of aphid probing and feeding by novel β-damascone analogues
  19. 6119
    “…We find that the least vulnerable cantons concentrate around Ecuador’s largest cities (e.g. …”
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    Assessing local vulnerability to climate change in Ecuador
  20. 6120
    “…The proapoptotic properties of the sesquiterpene lactones were additionally demonstrated withannexin V staining. …”
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    Investigation of the Antiproliferative Properties of Natural Sesquiterpenes from Artemisia asiatica and Onopordum acanthium on HL-60 Cells in Vitro
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