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  1. 6121
    “…N-acyl-homoserine lactones (AHLs) are small diffusible molecules called autoinducers that mediate cell-to-cell communications. …”
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    Engineering of a thermostable esterase Est816 to improve its quorum-quenching activity and the underlying structural basis
  2. 6122
    “…BACKGROUND: Macrocyclic lactones are arguably the most successful chemical class with efficacy against parasitic nematodes. …”
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    Coherent anti‐Stokes Raman scattering (CARS) spectroscopy in Caenorhabditis elegans and Globodera pallida: evidence for an ivermectin‐activated decrease in lipid stores
  3. 6123
    “…First, we examined the geographical distribution of Big Five personality traits in Switzerland. Across the 26 Swiss cantons, unique patterns were observed for all traits. …”
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    Regional Cultures and the Psychological Geography of Switzerland: Person–Environment–Fit in Personality Predicts Subjective Wellbeing
  4. 6124
    “…BACKGROUND: Sesquiterpene lactones are plant-derived, natural, bioactive molecules often used against inflammatory diseases in traditional Chinese medicines. …”
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    Brevilin A promotes oxidative stress and induces mitochondrial apoptosis in U87 glioblastoma cells
  5. 6125
    “…Here, we used two lactonases both targeting the signal molecules N-(3-oxododecanoyl)-L-homoserine lactone (3-oxo-C(12) HSL) and butyryl-homoserine lactone (C(4) HSL) albeit with different efficacies on C(4) HSL. …”
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    Lactonase Specificity Is Key to Quorum Quenching in Pseudomonas aeruginosa
  6. 6126
    “…The addition of L-gulono-1,4-lactone, an AsA precursor in the mammalian pathway, significantly increased AsA level in C. elegans, whereas the addition of L-galactono-1,4-lactone, an AsA precursor in the plant and Euglena pathway, did not affect AsA level. …”
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    L-Ascorbate Biosynthesis Involves Carbon Skeleton Rearrangement in the Nematode Caenorhabditis elegans
  7. 6127
    “…Since many sesquiterpene lactones with α-methylene γ-lactone ring are reported as anti-inflammatory and anticancer agents, eupatoriopicrin (10), 1-hydroxy-8-(4,5-dihydroxytigloyloxy)eudesma-4(15),11(13)-dien-6,12-olide (11) were selected among the isolates for biological assays. …”
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    Chemical Constituents of Eupatorium japonicum and Anti-Inflammatory, Cytotoxic, and Apoptotic Activities of Eupatoriopicrin on Cancer Stem Cells
  8. 6128
    “…PK blood samples were collected up to 24 h after the last dose, and PK parameters for atorvastatin, 2-hydroxyatorvastatin and atorvastatin lactone were estimated by a non-compartmental method. …”
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    Co-Administration of Vonoprazan, Not Tegoprazan, Affects the Pharmacokinetics of Atorvastatin in Healthy Male Subjects
  9. 6129
    “…The progressive introduction of regional mammography programs by 12 out of the 26 Swiss cantons (regions) since 1999 offers an opportunity to perform an ecological quasi-experimental study. …”
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    Revisiting the Effects of Organized Mammography Programs on Inequalities in Breast Screening Uptake: A Multilevel Analysis of Nationwide Data From 1997 to 2017
  10. 6130
    por Piccoli, Lorenzo, Wanner, Philippe
    Publicado 2022
    “…Second, we test whether there is an association between cantonal authorities’ policies and differing mortality patterns. …”
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    The political determinants of the health of undocumented immigrants: a comparative analysis of mortality patterns in Switzerland
  11. 6131
    “…Macrocyclic lactones are agonists of the nematode glutamate‐gated chloride channels (GluCls). …”
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    Pharmacological characterization of novel heteromeric GluCl subtypes from Caenorhabditis elegans and parasitic nematodes
  12. 6132
    por CAVAZZA, Marina
    Publicado 2022
    “…Founded by the Swiss Confederation and the Republic and Canton of Geneva, the International Geneva Welcome Centre is the single entry point for the support and integration of employees of International Geneva and their families, NGOs and visiting delegates.…”
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    Inauguration of the CAGI Welcome Centre of International Geneva
  13. 6133
    “…A new and efficient method for the synthesis of hexahydropyrimidine-fused 1,4-naphthoquinones in one step with high yields from the reaction of lawsone with 1,3,5-triazinanes was developed.…”
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    A new and efficient procedure for the synthesis of hexahydropyrimidine-fused 1,4-naphthoquinones
  14. 6134
    “…Hexane and methanol extracts of clove inhibited the response of C. violaceum CV026 to exogenously supplied N‐hexanoylhomoserine lactone, in turn preventing violacein production. …”
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    Inhibition of Quorum Sensing-Controlled Virulence Factor Production in Pseudomonas aeruginosa PAO1 by Ayurveda Spice Clove (Syzygium Aromaticum) Bud Extract
  15. 6135
    “…We verified that caffeine did not degrade the N-acyl homoserine lactones tested. In this work, it is shown that caffeine could inhibit N-acyl homoserine lactone production and swarming of a human opportunistic pathogen, namely Pseudomonas aeruginosa PA01. …”
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    Caffeine as a Potential Quorum Sensing Inhibitor
  16. 6136
    “…In this paper was described Health Information System (HIS) of Tuzla Canton and Brčko DC (whose citizens gravitate toward Tuzla Clinical Center). …”
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    E-Health in Bosnia - Starting from the Ground-Up
  17. 6137
    por Lenhart, Dominik, Bach, Thorsten
    Publicado 2014
    “…For the six-membered lactones and lactams and for cyclopentenone the simple addition products prevailed.…”
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    Visible-light-induced, Ir-catalyzed reactions of N-methyl-N-((trimethylsilyl)methyl)aniline with cyclic α,β-unsaturated carbonyl compounds
  18. 6138
    “…Using functionalized alkenes bearing a tethered nucleophile (alcohol, carboxylic acid, and sulfonamide), methylative cycloetherification, lactonization, and cycloamination processes are subsequently developed for the construction of important heterocycles such as 2,2-disubstituted tetrahydrofurans, tetrahydropyrans, γ-lactones, and pyrrolidines with concurrent generation of a quaternary carbon center. …”
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    Copper-catalyzed methylative difunctionalization of alkenes
  19. 6139
    “…Investigation of the ethanol extract of the whole plant of Ainsliaea yunnanensis led to the isolation of four new dimeric sesquiterpene lactones, ainsliadimer F–I (1–4), together with seven known dimeric sesquiterpene lactones (5–11) and ten sesquiterpenes (12–21). …”
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    New Sesquiterpenenoids from Ainsliaea yunnanensis
  20. 6140
    “…Modifications on tropone, lactone, and allyl positions of HO (1) were carried out to provide 17 derivatives (2–13, 11a–11f). …”
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    Semi-Synthesis of Harringtonolide Derivatives and Their Antiproliferative Activity
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