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  1. 6341
    “…The proteolytic activity of Pseudomonas fluorescens 07A was investigated, and was optimal on tryptone-calcium medium. N-acyl-homoserine lactones (AHLs) were not detected on supernatants of late-exponential and stationary-phase culture broths. …”
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    The proteolytic activity of Pseudomonas Fluorescens 07A isolated from milk is not regulated by quorum sensing signals
  2. 6342
    “…To this end we investigated an intramolecular variant of the thermal enamine [2 + 2] cyclisation, developing a diastereoselective intramolecular enamine [2 + 2] cyclisation furnishing δ lactone and lactam fused cyclobutenes in good yield and excellent diastereoselectivity.…”
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    Intramolecular thermal stepwise [2 + 2] cycloadditions: investigation of a stereoselective synthesis of [n.2.0]-bicyclolactones
  3. 6343
    por Wu, Ting, Pan, Zhiqiang, Xia, Chengfeng
    Publicado 2017
    “…Both the 3,3′-pyrrolidonyl spirooxindoles and spiroindolin-2-one δ-lactones were smoothly obtained by the intramolecular Dieckmann cyclization of oxindoles in excellent yield under mild conditions. …”
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    Construction of Spirooxindole Skeleton Through Intramolecular Dieckmann Cyclization
  4. 6344
    Publicado 2004
    “…Presented by Carlo Lamprecht, Head of the Department of Economy, Employment and External Affairs of the State of Geneva, the diploma was awarded in recognition of the 199 CERN apprentices Roland has guided through the Certificat Fédéral de Capacité (CFC), an end-of-apprenticeship certificate awarded by the Cantonal authorities. Roland will be retiring in December 2004 after 37 years of service, 32 of which he spent in the role of apprenticeship supervisor.…”
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    Hats off to CERN's Master of Apprenticeships ! Roland Gay of the HR Department (at right) recently received a special diploma from the Geneva Industrial Union (UIG).
  5. 6345
    “…The key steps of the synthesis include the concise preparation of the key intermediates 12a–b through the indium-mediated gem-difluoropropargylation of aldehyde 9 with the fluorine-containing building block 11 and the efficient construction of α,β-unsaturated-δ-lactones 15a–b via BAIB/TEMPO-procedure.…”
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    Synthesis of gem-difluoromethylenated analogues of boronolide
  6. 6346
    “…In the title mol­ecule, C(20)H(26)O(3), a clerodane diterpenoid isolated from Dodonaea viscosa­, the trans-fused six-membered rings of the deca­line system display chair conformations. The five-membered lactone ring adopts an envelope conformation and the five-membered furan ring is essentially planar with a maximum deviation of 0.0052 (12) Å.…”
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    7-[2-(3-Fur­yl)eth­yl]-7,8-dimethyl-3,5,6,6a,7,8,9,10-octa­hydro-1H-naphtho­[1,8a-c]furan-3-one
  7. 6347
    “…Highly virulent community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) with Panton-Valentine leukocidin (PVL) is common worldwide. …”
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    Community-acquired Methicillin-resistant Staphylococcus aureus in Children, Taiwan
  8. 6348
    “…This strain belongs to sequence type 772 (ST772), harbors the staphylococcal cassette chromosome mec element (SCCmec) type V, and is positive for the Panton-Valentine leukocidin (PVL) pathogenic determinant.…”
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    Draft Genome Sequence of Methicillin-Resistant Staphylococcus aureus KT/Y21, a Sequence Type 772 (ST772) Strain Isolated from a Pediatric Blood Sample in Terengganu, Malaysia
  9. 6349
    “…Genome annotation by BLAST searches revealed the presence of one acylhomoserine lactone (AHL) synthase (luxI) and five AHL receptor protein (luxR) gene homologs.…”
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    Draft Genome Sequence of Violacein-Producing Marine Bacterium Pseudoalteromonas sp. 520P1
  10. 6350
    “…Subsequent testing confirmed Panton-Valentine leukocidin-positive Staphylococcus aureus (PVL-SA). …”
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    “More than skin deep”: Recurrent primary hand abscesses in a warehouse operative
  11. 6351
    “…Its genome, estimated at 3,771,065 bp, encodes 3,535 coding sequences (CDSs), carrying genes for synthesis of auxins, homoserine lactones, enzymes, siderophores, and quorum sensing. …”
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    Genome Sequence of Pantoea sp. Strain 1.19, Isolated from Rice Rhizosphere, with the Capacity To Promote Growth of Legumes and Nonlegumes
  12. 6352
    por Rao, G Hari Mangeswara
    Publicado 2018
    “…The first approach to hyperireflexolide A, based on the synthesis of γ-lactone-fused cyclopentane 5, a functionalized key intermediate, is presented. …”
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    Studies towards the synthesis of hyperireflexolide A
  13. 6353
    “…These compounds were characterized as a group of macrolactones of operculinic acid A, and their lactonization site of 11S-hydroxyhexadecanoic acid was esterified at the second saccharide moiety (Rhamnose) at C-2. …”
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    Four Pentasaccharide Resin Glycosides from Argyreia acuta
  14. 6354
    “…We report a case of intractable arthritis of the shoulder joint caused by a multidrug-resistant Panton-Valentine leukocidin–positive livestock-associated MRSA clonal complex 398 sequence type 1232 clone in a patient in Japan who had no animal contact.…”
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    Arthritis Caused by MRSA CC398 in a Patient without Animal Contact, Japan
  15. 6355
    “…The genomes contain genes potentially involved in osmotic stress tolerance, DNA repair, monoacylglycerol hydrolysis, and beta-lactone synthesis.…”
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    Draft Genome Sequences of Micrococcus luteus MFP06 and MFP07, Isolated from the Skin of Healthy Volunteers
  16. 6356
    “…METHODS: We conducted a register study of all preschool children referred for EI in the Canton of Zurich, Switzerland, in 2017 (N = 1,785) and used an online survey among primary care physicians (PCPs, N = 271) to evaluate the care service of DD children. …”
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    The role of well-child visits in detecting developmental delay in preschool children
  17. 6357
    “…The presented PUR-PVA/TPT-PUR nanofibers appear to be promising carriers of active TPT lactone that could be useful for local cancer therapy.…”
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    Multilayered Polyurethane/Poly(vinyl alcohol) Nanofibrous Mats for Local Topotecan Delivery as a Potential Retinoblastoma Treatment
  18. 6358
    “…Considering this background, the work described herein reports the evaluation of the cytotoxicity of different acyl and alkyl derivatives from juglone and lawsone that showed the best activity results from a etiolated wheat coleoptile bioassay. …”
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    Biological Activity of Naphthoquinones Derivatives in the Search of Anticancer Lead Compounds
  19. 6359
    “…The methodology was applied to a modular and stereoselective total synthesis of the antiplatelet drug beraprost in only 8 steps from a key enal-lactone. This lactone provided the core of beraprost to which both its sidechains could be appended through a 1,4-conjugate addition process (lower ω-sidechain), followed by de novo construction of beraprost’s dihydrobenzofuran (upper α-sidechain) using our newly developed methodology. …”
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    De Novo Synthesis of Dihydrobenzofurans and Indolines and Its Application to a Modular, Asymmetric Synthesis of Beraprost
  20. 6360
    “…Among these, derivatives of 3-n-butylphthalide, a neuroprotective lactone from Apiaceae plants, may be prominent candidates. …”
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    Microbial Metabolites of 3-n-butylphthalide as Monoamine Oxidase A Inhibitors
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