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  1. 6421
    “…BACKGROUND: N-acylhomoserine lactones (AHLs) are well-studied signalling molecules produced by some Gram-negative Proteobacteria for bacterial cell-to-cell communication or quorum sensing. …”
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    Characterization of a novel N-acylhomoserine lactonase, AidP, from Antarctic Planococcus sp.
  2. 6422
    “…Methods Retrospective identification of patients who underwent primary emergency vitrectomies for retinal detachment at the Cantonal Hospital of Lucerne between 01.01.2018 – 31.12.2020. …”
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    Emergency Vitrectomies for Retinal Detachment Before and During the Coronavirus Pandemic – A Retrospective Single Centre Analysis
  3. 6423
    por Lawson Daku, Latévi M.
    Publicado 2020
    “…Two aqueous LS complexes were investigated in this framework, namely, [Fe(bpy)(3)](2+) (bpy = 2,2′-bipyridine) [Lawson Daku and Hauser, J. Phys. Chem. Lett., 2010, 1, 1830; Lawson Daku, Phys. …”
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    Spin-state dependence of the structural and vibrational properties of solvated iron(ii) polypyridyl complexes from AIMD simulations: III. [Fe(tpen)]Cl(2) in acetonitrile
  4. 6424
    “…In this report, we describe the successful treatment of vaginismus in a 25-year-old lady based on a model proposed by Keith Hawton. The eclectic approach involved education, graded insertion of fingers, Kegel's exercises and usage of local anesthesia with vaginal containment along with the prescription of Escitalopram.…”
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    Successful management of vaginismus: An eclectic approach
  5. 6425
    por Serrels, Bryan, Frame, Margaret C.
    Publicado 2012
    “…In this issue, Lawson et al. provide new insight into the relationship between FAK and talin during assembly of integrin adhesions on fibronectin. …”
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    FAK and talin: Who is taking whom to the integrin engagement party?
  6. 6426
    “…The compounds were prepared in a brief and efficient manner from thiophene-2-carbaldehyde using a ring-closing metathesis with Grubbs I or Grubbs II catalyst as the key step. The target lactones showed only insignificant cytotoxicity, while an intermediate simple thienyl carbinol showed very promising cytotoxicity.…”
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    Synthesis by Ring-Closing Metathesis and Cytotoxic Evaluation of Novel Thienylmacrolactones
  7. 6427
    “…The title compound, C(51)H(78)INO(12), contains a 29-membered ring incorporating amide, lactone and ester groups. It contains a total of 15 stereogenic centres. …”
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    40-De­oxy-40(S)-iodo­rapamycin
  8. 6428
    “…E6, which inhibits N-(3-oxododecanoyl)-l-homoserine lactone (3-oxo-C(12)-HSL)–mediated quorum sensing (QS), lasB transcription, and biofilm formation by Pseudomonas aeruginosa.…”
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    Draft Genome Sequence of Cellulophaga sp. E6, a Marine Algal Epibiont That Produces a Quorum-Sensing Inhibitory Compound Active against Pseudomonas aeruginosa
  9. 6429
    por Zhang, Huawei, Zhao, Ziping, Wang, Hong
    Publicado 2017
    “…This review for the first time provides a comprehensive overview of new cytotoxic agents from these marine microbes over the last 62 years from 1955 to 2016, which are assorted into seven types: terpenes, alkaloids, peptides, aromatics, lactones, steroids, and miscellaneous compounds.…”
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    Cytotoxic Natural Products from Marine Sponge-Derived Microorganisms
  10. 6430
    “…This methodology allows access to chiral γ-hydroxyaldehyde equivalents that were applied in the synthesis of chiral γ-lactones and 2,5-disubstitued tetrahydrofurans.…”
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    Development of a Strategy for Linear-Selective Cu-Catalyzed Reductive Coupling of Ketones and Allenes for the Synthesis of Chiral γ-Hydroxyaldehyde Equivalents
  11. 6431
    por Vu, Lan Phuong, Gütschow, Michael
    Publicado 2021
    “…[Image: see text] Diketomorpholines (DKMs; morpholine-2,5-diones) possess a six-membered ring with a lactone and lactam moiety and belong to the family of cyclodepsipeptides. …”
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    Diketomorpholines: Synthetic Accessibility and Utilization
  12. 6432
    “…The lactonization of 2-(2-nitrophenyl)-1,3-cyclohexanediones containing an alcohol side chain and up to three distant prochiral elements is reported by isomerization under the mediation of simple organocatalysts such as quinidine. …”
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    Organocatalyzed enantio- and diastereoselective isomerization of prochiral 1,3-cyclohexanediones into nonalactones bearing distant stereocenters
  13. 6433
    “…Two new apotirucallane triterpenoids, namely chisiamols G (1) and H (2), featuring a 21,23-lactone, together with five known triterpenoids, were isolated from the twigs of Chisocheton paniculatus. …”
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    New apotirucallane-type triterpenoids from Chisocheton paniculatus
  14. 6434
    “…In this approach to the cytotoxic C(2)-symmetric marine-derived bis(lactone) disorazole C(1), a highly convergent, modular strategy is employed featuring cyclization through an ambitious one-pot alkyne cross-metathesis/ring-closing metathesis self-assembly process.…”
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    Self-Assembly of Disorazole C(1) through a One-Pot Alkyne Metathesis Homodimerization Strategy**
  15. 6435
    “…Stereo- and chemodivergent enantioselective reaction pathways are observed upon treatment of alkylarylketenes and trichloroacetaldehyde (chloral) with N-heterocyclic carbenes, giving selectively either β-lactones (up to 88:12 dr, up to 94 % ee) or α-chloroesters (up to 94 % ee). …”
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    Stereo- and Chemodivergent NHC-Promoted Functionalisation of Arylalkylketenes with Chloral**
  16. 6436
    “…In this approach to the cytotoxic C(2)‐symmetric marine‐derived bis(lactone) disorazole C(1), a highly convergent, modular strategy is employed featuring cyclization through an ambitious one‐pot alkyne cross‐metathesis/ring‐closing metathesis self‐assembly process.…”
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    Self‐Assembly of Disorazole C(1) through a One‐Pot Alkyne Metathesis Homodimerization Strategy
  17. 6437
    “…These consist mainly of terpenoids (sesquiterpene lactones and dimmers, diterpenes and triterpenoids) and flavonoids. …”
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    Secondary Metabolites from Inula britannica L. and Their Biological Activities
  18. 6438
    “…A series of eight substituted bis-2-hydroxy-1,4-naphthoquinone derivatives was synthesized through lawsone condensation with various aromatic and aliphatic aldehydes under mild acidic conditions. …”
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    Synthesis, Leishmanicidal Activity and Theoretical Evaluations of a Series of Substituted bis-2-Hydroxy-1,4-Naphthoquinones
  19. 6439
    “…Computational chemistry approaches for studying the formation of terpenes/terpenoids in wines are presented, using five particular terpenes/terpenoids (1,8-cineole, α-ylangene, botrydial, rotundone, and the wine lactone), volatile compounds (or their precursors) found in wine and/or wine grapes, as representative examples. …”
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    Carbocations and the Complex Flavor and Bouquet of Wine: Mechanistic Aspects of Terpene Biosynthesis in Wine Grapes
  20. 6440
    “…A route to medium-ring lactones was also developed.…”
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    Seven-Membered Rings through Metal-Free Rearrangement Mediated by Hypervalent Iodine
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