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6541“…The A and B rings have chair conformations, whereas the C and D rings have envelope conformations; the two rings which contain the lactone and carbonyl bridge adopt chair and envelope conformations. …”
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6542por Jenkinson, Sarah F., Booth, K. Victoria, Best, Daniel, Fleet, George W. J., Watkin, David J.“…The absolute configuration was inferred from the use of d-erythronolactone as the starting material.…”
Publicado 2008
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6543por Jenkinson, Sarah F., Best, Daniel, Wilson, Francis X., Fleet, George W. J., Watkin, David J.“…The absolute configuration was determined by the use of d-glucorono-3,6-lactone as the starting material. The crystal structure consists of hydrogen-bonded chains of molecules running parallel to the a axis. …”
Publicado 2008
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6544por Jenkinson, Sarah F., Cruz, Filipa P., Booth, Kathrine V., Fleet, George W. J., Izumori, Ken, Yu, Chu-Yi, Watkin, David J.“…Addition of methyl lithium to d-erythrono-1,4-lactone followed by acid deprotection was shown, by X-ray crystallography, to give 1-deoxy-d-arabinitol, C(5)H(12)O(4), rather than 1-deoxy-d-ribitol as the major product. …”
Publicado 2008
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6545“…The title compound, C(15)H(20)O(3), a sesquiterpene lactone, was isolated from the aerial parts of Carpesium minus Hemsl. …”
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6546por Yousuf, Sammer, Younas, Syed M., Ambreen, Nida, Khan, Khalid M., Miana, Ghulam A.“…The trans-fused cyclohexane and γ-lactone rings of the α-santonin ring system adopt chair and envelope conformations, respectively, whereas the hexadiene ring is approximately planar [maximum deviation = 0.029 (4) Å] and forms a dihedral angle of 62.30 (11)° with the benzene ring. …”
Publicado 2012
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6547“…Two new eudesmane-type sesquiterpenoid lactones, named chlorelactone A (1) and chlorelactone B (2), and one new labdane-type diterpenoid, named elatiorlabdane (3), along with seven known sesquiterpenoids and one known disesquiterpenoid were isolated from the whole plants of Chloranthus elatior. …”
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6548“…Cimyunnins A–C (1–3), characterized with an unusual fused cyclopentenone ring G, together with cimyunnin D (4), possessing a highly rearranged γ-lactone ring F, were characterized from the fruit of Cimicifuga yunnanensis. …”
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6549“…In recent years, a considerable number of structurally unique metabolites with biological and pharmacological activities have been isolated from the marine-derived fungi, such as polyketides, alkaloids, peptides, lactones, terpenoids and steroids. Some of these compounds have anticancer, antibacterial, antifungal, antiviral, anti-inflammatory, antioxidant, antibiotic and cytotoxic properties. …”
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6550“…A new species of Hamacreadium Linton, 1910, H. cribbi n. sp. is described from Lethrinus miniatus (Forster) from the waters off New Caledonia. …”
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6551“…The starting materials for the reductions are, respectively, 1,2-O-isopropylidene-d-glucurono-6,3-lactone, 5-aldo-1,2-O-isopropylidene-d-xylo-pentofuranose, and 2,3:5,6-di-O-isopropylidene-d-mannofuranose. …”
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6552por Langer, Vratislav, Gyepesová, Dalma, Koman, Marian, Kapitán, Peter, Babjak, Matej, Gracza, Tibor, Koóš, Miroslav“…The conformation of both 5-membered lactone and furanose fused rings is also discussed.…”
Publicado 2003
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6553“…This is the first time that the known phenolics syringaldehyde and syringaresinol, as well as the known sesquiterpene lactones glucozaluzanin C, cichorioside C and hypochoeroside A have been described from a Picris species. …”
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6554por Rosselli, Sergio, Bruno, Maurizio, Raimondo, Francesco Maria, Spadaro, Vivienne, Varol, Mehmet, Koparal, Ayşe Tansu, Maggio, Antonella“…Five known sesquiterpene lactones with the eudesmane skeleton have been isolated and the cytotoxic activity of these compounds was tested in vitro on A549 (human lung carcinoma epithelial-like) and V79379A (Chinese hamster lung fibroblast-like) cells using the tetrazolium salt reduction (MTT) assay. …”
Publicado 2012
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6555“…The key features of this synthesis include Evans anti-aldol reaction for the installation of C-2 and C-3 stereocenters and cycloetherification via epoxide opening followed by concomitant lactonization for the construction of tetrahydrofuran and γ-butyrolactone scaffolds. …”
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6556por Ghosh, Kiron Kumar, Uttry, Alexander, Mondal, Arup, Ghiringhelli, Francesca, Wedi, Philipp, van Gemmeren, Manuel“…Through an intramolecular Michael addition, δ‐lactones are obtained as products. Two distinct ligand classes are identified that enable the challenging palladium‐catalyzed activation of free carboxylic acids in the γ‐position. …”
Publicado 2020
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6557“…This case explores Apligraf (Organogenesis Inc., Canton, Massachusetts) as an alternative treatment for full-thickness skin injuries in the pediatric population. …”
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6558por Lazzarotto, Mattia, Hartmann, Peter, Pletz, Jakob, Belaj, Ferdinand, Kroutil, Wolfgang, Payer, Stefan E., Fuchs, Michael“…Compared to the previous lactone reagent the stereopreference switches almost completely, proving the fact that the nature of the organometallic compound is of immense importance for the asymmetry of the product. …”
Publicado 2021
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6559“…The reaction proceeds via cascade C–H activation, carbene insertion, and intramolecular lactonization. The reaction exhibits high atom economy, good functional group tolerance, and high regioselectivity. …”
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6560“…[Image: see text] Commercially available and inexpensive lithium tert-butoxide ((t)BuOLi) acts as a good precatalyst for the hydroboration of esters, lactones, and epoxides using pinacolborane as a borylation agent. …”
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