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  1. 6681
    “…A multivariable model was used to determine if sex, age, breed, canton, or stable had a significant effect on the shedding status of each detected eGHV. …”
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    Prevalence of Nasal Shedding of Equid Gammaherpesviruses in Healthy Swiss Horses
  2. 6682
    “…[Image: see text] Baeyer–Villiger monooxygenases (BVMOs) catalyze the oxidation of ketones to lactones under very mild reaction conditions. This enzymatic route is hindered by the requirement of a stoichiometric supply of auxiliary substrates for cofactor recycling and difficulties with supplying the necessary oxygen. …”
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    Photobiocatalytic Oxyfunctionalization with High Reaction Rate using a Baeyer–Villiger Monooxygenase from Burkholderia xenovorans in Metabolically Engineered Cyanobacteria
  3. 6683
    “…Strong inhibition of graft establishment was observed only with D-glucono-1,5-lactone, thus suggesting the important role of GH9B3 in P. hybrida grafting. …”
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    Discovery of the interfamily grafting capacity of Petunia, a floricultural species
  4. 6684
    “…METHODS: We applied a Bayesian multilevel model with five levels to adjust for patients, drugs’ market, and physicians ‘characteristics, treatment type, and district (i.e. Swiss canton). We used data of the Swiss drugs’ market in 2006, offering real choices for doctors and patients (multiple products for similar active substances), with a neutral position of pharmacists (no financial incentives). …”
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    Determinants of drug expenditure in the Swiss healthcare market in 2006
  5. 6685
    “…The K-means analysis revealed that esters/lactones, including acetic acid, octyl ester, δ-octalactone, and δ-decalactone, were more abundant in HA and PA than in NA. …”
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    Transcriptomic and Metabolomic Analyses Provide Insights into the Formation of the Peach-like Aroma of Fragaria nilgerrensis Schlecht. Fruits
  6. 6686
    “…The in silico studies revealed that, out of the ten compounds, three of them—viz., Z-guggulsterone, dehydrocostus lactone and crocin—showed good binding efficiency with the HCC and ER stress proteins. …”
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    Z-Guggulsterone Is a Potential Lead Molecule of Dawa-ul-Kurkum against Hepatocellular Carcinoma
  7. 6687
    “…We demonstrate that oridonin suppressed cis-2-dodecenoic acid (BDSF) and N-acyl homoserine lactone (AHL) signal production and attenuated virulence in B. cenocepacia. …”
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    Oridonin Attenuates Burkholderia cenocepacia Virulence by Suppressing Quorum-Sensing Signaling
  8. 6688
    “…A series of naphthoquinones, namely, 1,4-naphthoquinone, menadione, plumbagin, juglone, naphthazarin, and lawsone, were reacted with N-acetyl-L-cysteine, and except for lawsone, which did not react, the related adducts were obtained. …”
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    Synthesis of thia-Michael-Type Adducts between Naphthoquinones and N-Acetyl-L-Cysteine and Their Biological Activity
  9. 6689
    “…Currently, most anti-cancer studies reporting the effects of sophorolipids have focused on lactonic preparations with the effects of acidic sophorolipids yet to be elucidated. …”
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    Microbial sophorolipids inhibit colorectal tumour cell growth in vitro and restore haematocrit in Apc(min+/−) mice
  10. 6690
    “…METHODS: Our analysis exploited the fact that between July and October 2020, nine cantons in Switzerland extended a face-mask mandate at different time points from being restricted to public transportation only to applying to all public indoor places. …”
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    The impact of face-mask mandates on all-cause mortality in Switzerland: a quasi-experimental study
  11. 6691
    por Nielsen, M.K.
    Publicado 2022
    “…Resistance to benzimidazoles and pyrimidines is highly prevalent in cyathostomin populations around the world, and macrocyclic lactone resistance has been documented in cyathostomins in recent years as well. …”
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    Anthelmintic resistance in equine nematodes: Current status and emerging trends
  12. 6692
    “…The present review summarizes a number of synthetic methodologies, including stereoselective and regioselective pathways adopted by scientists, for framing medium- to large-size carbo- and heterocycles involving lactams, lactone, azepine and azulene derivatives via ring expansion of six-membered carbo- and heterocycles that have been reported from 2007–2022. …”
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    Synthetic Potential of Regio- and Stereoselective Ring Expansion Reactions of Six-Membered Carbo- and Heterocyclic Ring Systems: A Review
  13. 6693
    “…[Image: see text] Despite recent advancements in the development of catalytic asymmetric electrophile induced lactonization reactions of olefinic carboxylic acids, the archetypical hydrolactonization has long remained an unsolved and well-recognized challenge. …”
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    A Catalytic Asymmetric Hydrolactonization
  14. 6694
    “…The combination of inexpensive Fe(ii) acetate with low molecular weight aliphatic carboxamides in situ generates an effective catalyst system for the ring opening polymerisation of lactones. PLLAs were produced in melt conditions with molar masses of up to 15 kg mol(−1), narrow dispersity (Đ = 1.03), and without racemisation. …”
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    Iron(ii) carboxylates and simple carboxamides: an inexpensive and modular catalyst system for the synthesis of PLLA and PLLA-PCL block copolymers
  15. 6695
    por Mankaev, Badma N., Karlov, Sergey S.
    Publicado 2023
    “…Also, a separate chapter is devoted to the study of metal complexes in the synthesis of copolymers of lactide and lactones. This review highlights the efforts made over the last ten years or so, and shows how main-group metals have received increasing attention in the field of the polymerization of lactide and related cyclic esters.…”
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    Metal Complexes in the Synthesis of Biodegradable Polymers: Achievements and Prospects
  16. 6696
    “…Mycolactones are characterized by a common 12-membered lactone core to which is appended an unsaturated fatty acyl side-chain of variable length and oxidation state. …”
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    Mycolactones: immunosuppressive and cytotoxic polyketides produced by aquatic mycobacteria
  17. 6697
    “…Upon ester hydrolysis, unfavorable steric interactions between the three methyl groups of this o-hydroxycinnamic acid derivative encourage rapid lactonization to form a hydrocoumarin and release p-nitroaniline. …”
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    Trimethyl Lock: A Stable Chromogenic Substrate for Esterases
  18. 6698
    “…In 2002 a consensus statement pertaining to the management of classical congenital adrenal hyperplasia due to 21-hydroxylase deficiency was jointly produced by the Lawson Wilkins Pediatric Endocrine Society and the European Society of Pediatric Endocrinology. …”
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    An Evidence-Based Model of Multidisciplinary Care for Patients and Families Affected by Classical Congenital Adrenal Hyperplasia due to 21-Hydroxylase Deficiency
  19. 6699
    “…The title furan­oditerpenoid, known as fibaruretin B (systematic name: 2β,3α-dihy­droxy-2,3,7,8α-tetra­hydro­penianthic acid lactone), C(20)H(24)O(7), was isolated from the roots of Arcangelisia flava. …”
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    Absolute configuration of fibaruretin B
  20. 6700
    “…In the title compound C(27)H(19)ClO(6), the coumarin ring system is not exactly planar, with a dihedral angle of 4.12 (7)° between its benzene and lactone rings. The cis-fused pyran rings adopt half-chair conformations. …”
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    Methyl rac-(2R,11S,12R)-12-(2-chloro­phen­yl)-22-oxo-9,13,21-trioxapenta­cyclo­[12.8.0.0(2,11).0(3,8).0(15,20)]docosa-1(14),3,5,7,15(20),16,18-hepta­ene-11-carboxyl­ate
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