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6881por Laurella, Laura C., Frank, Fernanda M., Sarquiz, Andrea, Alonso, María R., Giberti, Gustavo, Cavallaro, Lucia, Catalán, Cesar A., Cazorla, Silvia I., Malchiodi, Emilio, Martino, Virginia S., Sülsen, Valeria P.“…The chromatographic profile and infrared analysis of these fractions revealed the presence of sesquiterpene lactones. None of the tested extracts were active against dengue virus type 2.…”
Publicado 2012
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6882por Piccialli, Vincenzo, Oliviero, Giorgia, Zaccaria, Sabrina, Centore, Roberto, Tuzi, Angela“…The title compound, C(20)H(16)O(7), contains a cis-fused γ-lactone tetrahydrofuran ring system functionalized with two benzoyloxy groups. …”
Publicado 2013
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6883“…The title compound, C(22)H(29)NO(4), a stemona alkaloid, is composed of two lactone rings (A and E), a six-membered ring (B), a pyrrole ring (C) and a seven-membered ring (D). …”
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6884por Kim, Suyoung, Lee, Kang Lock, Baek, Hae Lim, Jang, Seung Jun, Moon, Song Mi, Cho, Yong Kyun“…The pathogen carried the type IV-A staphylococcal cassette chromosome mec (SCCmec) without the Panton-Valentine leukocidin (PVL) gene, and was identified as sequence type (ST) 72 by multilocus sequence typing.…”
Publicado 2013
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6885por Beyersmann, Paul G., Chertkov, Olga, Petersen, Jörn, Fiebig, Anne, Chen, Amy, Pati, Amrita, Ivanova, Natalia, Lapidus, Alla, Goodwin, Lynne A., Chain, Patrick, Detter, John C., Rohde, Manfred, Gronow, Sabine, Kyrpides, Nikos C., Woyke, Tanja, Simon, Meinhard, Göker, Markus, Klenk, Hans-Peter, Brinkhoff, Thorsten“…Here we report of putative quorum sensing systems, based on the finding of six N-acyl-homoserine lactone synthetases, and show that the blue color of P. caeruleus is probably due to the production of the secondary metabolite indigoidine. …”
Publicado 2013
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6886por Nayak, Sudhir, Fiaschi, Michela, King, Dana, Tabakin, Erica R., Wood, Lyndsay, Hunt, David A.“…This basic protocol is amenable to a high throughput (96-well) format and has been used successfully to identify multiple compounds for further analysis based on structural elements from the naturally occurring compounds lactacystin and the β-lactone homologs omuralide and salinosporamide A. …”
Publicado 2014
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6887por Zaytsev, Vladimir P., Orlova, Daria N., Gurbanov, Atash V., Zubkov, Fedor I., Khrustalev, Victor N.“…The central diazepane ring has a distorted boat conformation with two phenylene-fused and one methine C atom deviating by 0.931 (1), 0.887 (1) and 0.561 (1) Å, respectively, from the mean plane of the rest of the ring. The γ-lactone ring has an envelope conformation, with the C atom opposite to amide bond deviating by 0.355 (1) Å from its plane. …”
Publicado 2014
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6888por Wan, T.-W., Tomita, Y., Saita, N., Konno, K., Iwao, Y., Hung, W.-C., Teng, L.-J., Yamamoto, T.“…His CA-MRSA was an emerging type, originated in ST121/agr4 S. aureus, with diversities of Panton–Valentine leucocidin (PVL)(−)/spat5110/SCCmecV(+) versus PVL(+)/spat159((etc.))…”
Publicado 2016
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6889“…We describe the first pediatric case in Scandinavia with Panton-Valentine leucocidin (PVL) positive MRSA septicemia who developed bilateral pneumonia, arthritis of the knee, and osteomyelitis of the tibia. …”
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6890por Ai, Xiao-Yu, Zhang, Heng, Gao, Shao-Yan, Qin, Yuan, Zhong, Wei-Long, Gu, Ju, Li, Meng, Qiao, Kai-Liang, Tian, Qin, Cui, Zhan-Hong, Yang, Jia-Huan, Bi, Zhun, Xiao, Ting, Chen, Shuang, Liu, Hui-Juan, Zhou, Hong-Gang, Sun, Tao, Yang, Cheng“…Sesquiterpene lactones (SL) have a wide range of applications in anti-tumor and anti-inflammatory therapy. …”
Publicado 2017
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6891“…On the basis of shared responsibilities between the Federal State and the 26 cantons, this article describes the Swiss legal and regulatory approach to the right to health, the ways it is currently implemented and the possible vectors for an improved integration of migrants into the health system.…”
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6892por Guillen, Paul O., Calabro, Kevin, Jaramillo, Karla B., Dominguez, Cristobal, Genta-Jouve, Grégory, Rodriguez, Jenny, Thomas, Olivier P.“…The four compounds of this family of ecdysteroids feature an unprecedented γ-lactone fused at the C-2/C-3 position of ring A. These derivatives exhibited neither antimicrobial nor cytotoxic activities.…”
Publicado 2018
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6893por Wang, Zhen-Xiong, Qin, Shen, Xu, Li-Hua, Chen, He-Ping, Sun, Huan, Huang, Rong, Li, Zheng-Hui, Feng, Tao, Liu, Ji-Kai“…ABSTRACT: Three new lactones, xylanilyticolides A–C (1–3), were isolated from cultures of the actinomycete Promicromonospora xylanilytica YIM 61515. …”
Publicado 2018
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6894“…Here we have achieved the syntheses of homochiral porous molecular solids composed of helical metal macrocycles through supramolecular chirality induction to both enantiomorphic forms with the aid of two different enantiopure sugar-derived lactones in the crystallization process. Moreover, we found that the helicity of the macrocyclic skeletons can be inverted in the crystalline state only by changing the type of solvent. …”
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6895por De Mieri, Maria, Smieško, Martin, Ismajili, Isidor, Kaiser, Marcel, Hamburger, Matthias“…The acid-induced rearrangement of three epoxyderivatives of nobilin 1, the most abundant sesquiterpene lactone in Anthemis nobilis flowers, was investigated. …”
Publicado 2017
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6896“…Docking experiments showed that the 2-substituted aniline motif fits within the LuxR binding site at the place of the lactone moiety of AHL, and the biological evaluation revealed QS antagonisitic activity for several compounds, validating the hypothesis that this scaffold acts on QS. …”
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6897por Parthasarathy, Anutthaman, Gan, Han Ming, Wong, Narayan H., Savka, Michael A., Steiner, KayLee K., Henry, Kurtis R., Hudson, André O.“…In addition, we were able to show that one of the organisms, Enterobacter sp RIT418 produces N-acyl-homoserine lactones (AHLs), which is indicative of cell-cell communication via quorum sensing (QS).…”
Publicado 2018
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6898por Kan, Ze, Luo, Wenlong, Shi, Tong, Wei, Chuanzhi, Han, Binghao, Zheng, Dejuan, Liu, Shaofeng“…Ring-opening polymerization (ROP) of cyclic esters/lactones by efficient catalysts is a powerful method for synthesis of biodegradable and biocompatible polyesters with well-defined structures. …”
Publicado 2018
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6899“…Parthenolide, the principal component of sesquiterpene lactones present in medical plants such as feverfew (Tanacetum parthenium), has been reported to have anti-tumor activity. …”
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6900“…Overall, the review demonstrates that e-ROP of lactones or lactides could be an effective method for the synthesis of useful biomedical polymers.…”
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