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7141por Kawahara, Takashi, Ito, Hiroki, Terao, Hideyuki, Kato, Yoshitake, Ogawa, Takehiko, Uemura, Hiroji, Kubota, Yoshinobu, Matsuzaki, Junichi“…A flexible ureteroscope (URS) was inserted, and a Lawson retrograde nephrostomy puncture wire was advanced into the flexible URS. …”
Publicado 2012
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7142“…SdiA of E. coli and Salmonella is a LuxR homolog that detects N-acyl homoserine lactones (AHLs). Most LuxR homologs function together with a cognate AHL synthase (a LuxI homolog), but SdiA does not. …”
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7143por Schmid, Nadine, Pessi, Gabriella, Deng, Yinyue, Aguilar, Claudio, Carlier, Aurelien L., Grunau, Alexander, Omasits, Ulrich, Zhang, Lian-Hui, Ahrens, Christian H., Eberl, Leo“…Quorum sensing in Burkholderia cenocepacia H111 involves two signalling systems that depend on different signal molecules, namely N-acyl homoserine lactones (AHLs) and the diffusible signal factor cis-2-dodecenoic acid (BDSF). …”
Publicado 2012
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7144por Bai, Yunpeng, Patil, Santoshkumar N., Bowden, Steven D., Poulter, Simon, Pan, Jie, Salmond, George P. C., Welch, Martin, Huck, Wilhelm T. S., Abell, Chris“…Escherichia coli transformed to express the quorum sensing receptor protein, LasR, were encapsulated in microdroplets that were positioned adjacent to microdroplets containing the autoinducer, N-(3-oxododecanoyl)- l-homoserine lactone (OdDHL). Functional activation of the LasR protein by diffusion of the OdDHL across the droplet interface was measured by monitoring the expression of green fluorescent protein (GFP) from a LasR-dependent promoter. …”
Publicado 2013
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7145“…The bacterial signalling and response system known as quorum sensing or Acylated Homoserine Lactone (AHL) mediated gene expression is thought to have evolved through kin selection. …”
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7146por Choudhary, Kumari Sonal, Hudaiberdiev, Sanjarbek, Gelencsér, Zsolt, Coutinho, Bruna Gonçalves, Venturi, Vittorio, Pongor, Sándor“…Quorum sensing via N-acyl homoserine lactone signals (AHL QS) is present in almost all Burkholderia species and is thought to play important roles in lifestyle changes such as colonization and niche invasion. …”
Publicado 2013
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7147por Tang, Kaihao, Zhang, Yunhui, Yu, Min, Shi, Xiaochong, Coenye, Tom, Bossier, Peter, Zhang, Xiao-Hua“…This method effectively eliminates false positives caused by inhibition of growth of biosensor A136 and alkaline hydrolysis of N-acylhomoserine lactones (AHLs), through normalization of β-galactosidase activities and addition of PIPES buffer, respectively. …”
Publicado 2013
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7148“…Adjustment of the oxidation state of the thus formed lactone allows introduction of the 2,3-dihydroxybenzoquinone moiety through a presumed benzoin-like condensation between a phthaldehyde derivative and a masked glyoxal equivalent catalyzed by a cyanide ion. …”
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7149por Nerin, C., Ubeda, J. L., Alfaro, P., Dahmani, Y., Aznar, M., Canellas, E., Ausejo, R.“…Chemical analysis of the suspicious bags identified unexpected compounds such as BADGE, a cyclic lactone and an unknown phthalate that leached into the semen at concentrations of 0.2 to 2.5 mg/L. …”
Publicado 2014
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7150por Vaverkova, Veronika, Vrana, Oldrich, Adam, Vojtech, Pekarek, Tomas, Jampilek, Josef, Babula, Petr“…Due to the cytotoxic properties of naphthoquinones, it is necessary to study the processes of naphthoquinones, DNA interactions (1,4-naphthoquinone, binapthoquinone, juglone, lawsone, plumbagin), especially by using modern analytical techniques. …”
Publicado 2014
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7151por Witzel, Claudia de Lima, Castelo Branco Fortaleza, Carlos Magno, Sena Martins de Souza, Camila, Moraes Riboli, Danilo Flávio, Ribeiro de Souza da Cunha, Maria de Lourdes“…Both harbored SCCmec IV, and did not possess the Panton-Valentine Leukocidin gene. CONCLUSION: We found low prevalence of S. aureus and CA-MRSA among prisoners. …”
Publicado 2014
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7152por Tan, Wen-Si, Yunos, Nina Yusrina Muhamad, Tan, Pui-Wan, Mohamad, Nur Izzati, Adrian, Tan-Guan-Sheng, Yin, Wai-Fong, Chan, Kok-Gan“…Chromobacterium violaceum CV026 and Escherichia coli [pSB401] were used for preliminary screening of N-acyl homoserine lactone (AHL) production. The Enterobacter sp. isolated was shown to produce two types of AHLs as confirmed by analysis using high resolution tandem mass spectrometry. …”
Publicado 2014
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7153por Carbonell-Ballestero, Max, Duran-Nebreda, Salva, Montañez, Raúl, Solé, Ricard, Macía, Javier, Rodríguez-Caso, Carlos“…As a proof of concept, we characterize a set of Lux homoserine-lactone-inducible genetic devices with different levels of Lux receptor and signal molecule. …”
Publicado 2014
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7154“…Here we show that QS signals (N-acyl-homoserine lactones, AHLs) are stochastically produced in young biofilms of Pseudomonas putida and act mainly as self-regulatory signals rather than inducing neighbouring cells. …”
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7155por Wei, Kun, Wang, Gang-Qiang, Bai, Xue, Niu, Yan-Fen, Chen, He-Ping, Wen, Chun-Nan, Li, Zheng-Hui, Dong, Ze-Jun, Zuo, Zhi-Li, Xiong, Wen-Yong, Liu, Ji-Kai“…The unusual fused β-lactone vibralactone was isolated from cultures of the basidiomycete Boreostereum vibrans and has been shown to significantly inhibit pancreatic lipase. …”
Publicado 2015
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7156por Jin, Xianqing, Qiu, Lin, Zhang, Dianliang, Zhang, Mingman, Wang, Ziming, Guo, Zhenhua, Deng, Chun, Guo, Chunbao“…In this study, we demonstrated with mechanistic evidence that parthenolide, a sesquiterpene lactone, could antagonize paclitaxel-mediated NF-κB nuclear translocation and activation by selectively targeting I-κB kinase (IKK) activity. …”
Publicado 2009
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7157“…Quorum sensing (QS) is a widespread intercellular form of communication to coordinate physiological processes and cooperative activities of bacteria at the population level, and it depends on the production, secretion, and detection of small diffusible autoinducers, such as acyl-homoserine lactones (AHLs), auto-inducing oligo-peptides (AIPs) and autoinducer 2. …”
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7158“…Here we characterize the Turing instability in a specific gene circuit that can be implemented in vitro or in populations of clonal cells producing short-range activator N-Acyl homoserine lactone (AHL) and long-range inhibitor hydrogen peroxide (H(2)O(2)) gas. …”
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7159por Miettinen, Karel, Pollier, Jacob, Buyst, Dieter, Arendt, Philipp, Csuk, René, Sommerwerk, Sven, Moses, Tessa, Mertens, Jan, Sonawane, Prashant D, Pauwels, Laurens, Aharoni, Asaph, Martins, José, Nelson, David R., Goossens, Alain“…Here we characterize CYP716 enzymes from different medicinal plant species by heterologous expression in engineered yeasts and report ten hitherto unreported triterpenoid oxidation activities, including a cyclization reaction, leading to a triterpenoid lactone. Kingdom-wide phylogenetic analysis of over 400 CYP716s from over 200 plant species reveals details of their evolution and suggests that in eudicots the CYP716s evolved specifically towards triterpenoid biosynthesis. …”
Publicado 2017
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7160por El-Aouar Filho, Rachid A., Nicolas, Aurélie, De Paula Castro, Thiago L., Deplanche, Martine, De Carvalho Azevedo, Vasco A., Goossens, Pierre L., Taieb, Frédéric, Lina, Gerard, Le Loir, Yves, Berkova, Nadia“…We discuss the mechanisms of actions of cyclomodulins according to their biochemical properties, providing examples of various cyclomodulins such as cycle inhibiting factor, γ-glutamyltranspeptidase, cytolethal distending toxins, shiga toxin, subtilase toxin, anthrax toxin, cholera toxin, adenylate cyclase toxins, vacuolating cytotoxin, cytotoxic necrotizing factor, Panton-Valentine leukocidin, phenol soluble modulins, and mycolactone. …”
Publicado 2017
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