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7161“…Here we show that the white (w) gene, a classical gene for eye color, is associated with copulation success. 82.5% of wild-type Canton-S flies copulated within 60 minutes in circular arenas, whereas few white-eyed mutants mated successfully. …”
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7162por Lebughe, Marthe, Phaku, Patrick, Niemann, Silke, Mumba, Dieudonné, Peters, Georg, Muyembe-Tamfum, Jean-Jacques, Mellmann, Alexander, Strauß, Lena, Schaumburg, Frieder“…The majority of the 79 virulence factors were equally distributed among isolates from colonization and infection. Panton-Valentine leukocidin (PVL) and the non-truncated hemolysin β were associated with skin and soft tissue infection (SSTI) and recurrence of disease but did not influence the course of infection (i.e., mortality, surgical intervention). …”
Publicado 2017
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7163por Li, Chun-Shun, Sarotti, Ariel M., Huang, Peng, Dang, Uyen T., Hurdle, Julian G., Kondratyuk, Tamara P., Pezzuto, John M., Turkson, James, Cao, Shugeng“…LC-UV/MS-based metabolomic analysis of the Hawaiian endophytic fungus Paraphaeosphaeria neglecta FT462 led to the identification of four unique mercaptolactated γ-pyranol–γ-lactams, paraphaeosphaerides E–H (1–4) together with one γ-lactone (5) and the methyl ester of compound 2 (11). …”
Publicado 2017
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7164“…The resulting products can be easily scaled up and directly converted to γ,δ-unsaturated or α,β-diaryl-acids, -esters, -amides, -pyrazoles, -isoxazoles, as well as lactones, which enables this mild and selective sp(3) C–H alkylation to rapidly access complex bioactive molecules.…”
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7165por Dixit, Swarnita, Dubey, Ramesh Chand, Maheshwari, Dinesh Kumar, Seth, Prahlad Kishore, Bajpai, Vivek K.“…The most abundant and biologically active N-acyl homoserine lactone molecules (3-oxo-C(8)-HSL and 3-OH-C(14)-HSL) were detected in the ethyl acetate extract of RT1. …”
Publicado 2017
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7166“…Minocycline-supplemented food significantly extended lifespan in both Canton S and w(1118) Drosophila strains. The drug-induced lifespan extension was not associated with reduced dietary intake or reduced female fecundity, but rather with increased resistance to an oxidative stressor (hydrogen peroxide). …”
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7167por Herrera-España, Angel D., Mena-Rejón, Gonzalo J., Hernández-Ortega, Simón, Quijano, Leovigildo, Mirón-López, Gumersindo“…The title compound, C(30)H(44)O(3) [systematic name: 6aR,6 bR,8aS,9aR,12aR,14bR)-4,4,6a,6;b,8a,14b-hexamethyl-12-methyleneicosahydro-3H-phenanthro[1′,2′:6,7]indeno[2,1-b]furan-3,11(2H)-dione], is a triterpene lactone, which was isolated from dichloromethane extract of Elaeodendron trichotomum (Turcz.) …”
Publicado 2017
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7168“…Inulin, coumarins, tannins, monomeric flavonoids, and sesquiterpene lactones are some of the major phytocompounds mostly found in chicory plants. …”
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7169por Feng, Quanyou, Yang, Lei, Zhong, Yongliang, Guo, Dong, Liu, Guoliang, Xie, Linghai, Huang, Wei, Tong, Rong“…Biodegradable polyesters with various tacticities have been synthesized by means of stereoselective ring-opening polymerization of racemic lactide and β-lactones but with limited side-chain groups. However, stereoselective synthesis of functional polyesters remains challenging from O-carboxyanhydrides that have abundant pendant side-chain functional groups. …”
Publicado 2018
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7170por Gauvin-Rossignol, Gabrielle, Legros, Philippe, Ruel, Jean, Fortin, Marc-André, Bégin-Drolet, André“…We used a dual calcium cross-linking process by adding this highly soluble calcium source in the printed sugar, thus allowing the rapid gelation of a thin membrane of alginate around the sugar construct, followed by the addition of calcium carbonate and gluconic acid δ-lactone to complete the process. This innovative technique results in the rapid formation of "on-demand" alginate hydrogel with complex fluidic channels that could be used in biomedical applications such as highly vascularized scaffolds promoting pathways for nutrients and oxygen to the cells.…”
Publicado 2018
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7171por Chen, Lin, Zhang, Jian-Ping, Liu, Xin, Tang, Jiang-Jiang, Xiang, Ping, Ma, Xing-Ming“…1β-hydroxy alantolactone, a sesquiterpene lactone mainly isolated from Inula genus plants, exhibits potent anti-inflammatory and anticancer activities. …”
Publicado 2017
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7172por Hodille, Elisabeth, Badiou, Cédric, Bouveyron, Caroline, Bes, Michèle, Tristan, Anne, Vandenesch, François, Lina, Gérard, Dumitrescu, Oana“…Here, we show that sub-MICs of clindamycin decrease Panton–Valentine leucocidin, toxic-shock-staphylococcal toxin (TSST-1) and alpha-haemolysin (Hla) expression in six inducible clindamycin-resistant isolates cultivated in vitro in CCY medium. …”
Publicado 2018
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7173por Cole, Stephanie J., Hall, Cherisse L., Schniederberend, Maren, Farrow III, John M., Goodson, Jonathan R., Pesci, Everett C., Kazmierczak, Barbara I., Lee, Vincent T.“…P. aeruginosa produces acyl homoserine lactones (AHLs) in the presence of urea, but cannot perceive AHLs. …”
Publicado 2018
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7174por Xiong, Xu-qiong, Zhao, Dong-mei, Bu, Peng-fei, Liu, Yang, Ren, Jin-hong, Wang, Jian, Cheng, Mao-sheng“…These derived models may help us to gain a deeper understanding of the binding interaction of these lactone-based compounds and aid in the design of new potent compounds against CETP.…”
Publicado 2008
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7175“…Two viridin-related B-norsteroids, B-norviridiol lactone (1) and B-norviridin enol (2), both possessing distinct unprecedented carbon skeletons, were isolated from a liquid culture of the ash dieback-causing fungus Hymenoscyphus pseudoalbidus. …”
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7176por Meier, Herbert“…Naphtho-condensed and higher condensed compounds and compounds with an exocyclic C=O or S=O double bond (lactones, thiolactones, sulfoxides and sulfones) are not covered in this article.…”
Publicado 2012
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7177por Rasul, Azhar, Bao, Rui, Malhi, Mahadev, Zhao, Bing, Tsuji, Ichiro, Li, Jiang, Li, Xiaomeng“…Costunolide, a member of sesquiterpene lactone family, possesses potent anticancer properties. …”
Publicado 2013
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7178por Andersen, Trine Bundgaard, López, Carmen Quiñonero, Manczak, Tom, Martinez, Karen, Simonsen, Henrik Toft“…The sesquiterpene lactone thapsigargin is found in the plant Thapsia garganica L., and is one of the major constituents of the roots and fruits of this Mediterranean species. …”
Publicado 2015
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7179por Pan, Jie-Tao, Yu, Bang-Wei, Yin, Yong-Qin, Li, Jie-Hong, Wang, Li, Guo, Li-Bing, Shen, Zhi-Bin“…The core of the six compounds was simonic acid A, and they were esterfied the same sites, just differing in the substituent groups. The lactonization site of the aglycone was bonded to the second saccharide moiety at C-2 in 1–4, and at C-3 in 5–6. …”
Publicado 2015
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7180por Jun, Joon‐Young, Jung, Min‐Jeong, Jeong, In‐Hak, Kim, Gwang‐Woo, Sim, Jae‐Man, Nam, Si‐Youl, Kim, Byoung‐Mok“…The tofu yields of all the acetic acid extracts were comparable with those of the commercial coagulants MgCl(2) and glucono‐δ‐lactone (GDL). Furthermore, the results for the textural attributes and sensorial acceptability demonstrated that either the extract from CSP prepared with 3% acetic acid or the extracts from CSA prepared with 1% or 3% acetic acid could be used as coagulants, because all the values of the extracts were statistically equivalent to those of the MgCl(2) and GDL (p < 0.05).…”
Publicado 2019
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