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7401por Li, Hongliang, Yang, Chang, Chen, Chong, Ren, Fazheng, Li, Yuan, Mu, Zhishen, Wang, Pengjie“…After being treated with microbial transglutaminase (mTGase), all dispersions were acidified with 1.3% (w/v) gluconodelta-lactone (GDL) to pH 4.4–4.6. As the concentration of trisodium citrate increased from 0 mmol/L to 30 mmol/L, the firmness and water-holding capacity increased significantly. …”
Publicado 2018
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7402por Osei-Safo, Dorcas, Dziwornu, Godwin Akpeko, Appiah-Opong, Regina, Chama, Mary Anti, Tuffour, Isaac, Waibel, Reiner, Amewu, Richard, Addae-Mensah, Ivan“…Also isolated were the known compounds friedelin-2,3-lactone (4), friedelan-3-one (6), friedelan-3β-ol (7) and pomolic (8), as well as the dipeptide aurantiamide acetate (5). …”
Publicado 2017
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7403por Semelakova, Martina, Grauzam, Stèphane, Betadthunga, Prabhakar, Tiedeken, Jessica, Coaxum, Sonya, Neskey, David M., Rosenzweig, Steven A.“…Treatment of cells with the vimentin-targeting steroidal lactone withaferin A had no effect on vimentin turnover as previously reported, instead causing NEDD9 cleavage and cell death. …”
Publicado 2018
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7404por Yao, Yuyuan, Guo, Qinglong, Cao, Yue, Qiu, Yangmin, Tan, Renxiang, Yu, Zhou, Zhou, Yuxin, Lu, Na“…Artemisinin (ART) is a sesquiterpene lactone extracted from Chinese herb qinghao, and artemether (ARM), artesunate (ARS) and dihydroartemisinin (DHA) were synthesized derivatives of artemisinin, which also have anti-malarial and anti-cancer effects such as artemisinin. …”
Publicado 2018
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7405por Espinosa-Valdés, Mariana Paola, Borbolla-Alvarez, Sara, Delgado-Espinosa, Ana Elena, Sánchez-Tejeda, Juan Francisco, Cerón-Nava, Anabelle, Quintana-Romero, Osvaldo Javier, Ariza-Castolo, Armando, García-Del Río, Diego Fernando, Loza-Mejía, Marco A.“…Based on the structure of 2-alkyl-3-hydroxy-4-quinolone and N-acylhomoserine lactone, molecules that act as mediators of quorum sensing and biofilm formation in Pseudomonas aeruginosa, we designed, prepared, and evaluated the biofilm inhibition properties of long chain amide derivatives of 2-amino-4-quinolone in Staphylococcus aureus and P. aeruginosa. …”
Publicado 2019
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7406por Deng, Yuyou, Bi, Ran, Guo, Haoran, Yang, Jiaxin, Du, Yujun, Wang, Chunxi, Wei, Wei“…Here, we identified Andrographolide, a diterpenoid lactone derived from a traditional herbal medicine Andrographis paniculata, as an ideal sensitizer for TRAIL to overcome bladder cancer. …”
Publicado 2019
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7407“…Gram-negative bacteria commonly use N-acyl homoserine lactones (AHLs) as their AIs, and they are detected by LuxR-type receptors. …”
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7408por Sülsen, Valeria P., Lizarraga, Emilio F., Elso, Orlando G., Cerny, Natacha, Sanchez Alberti, Andrés, Bivona, Augusto E., Malchiodi, Emilio L., Cazorla, Silvia I., Catalán, César A. N.“…Sesquiterpene lactones are naturally occurring compounds mainly found in the Asteraceae family. …”
Publicado 2019
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7409“…Here, it was hypothesized that ROP of lactones is possible with Fe(OAc)(2) when amides are present in the reactions mixture as Fe-ligands could increase the solubility and activity of the metal catalytic center. …”
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7410por Walker, Kenneth T., Goosens, Vivianne J., Das, Akashaditya, Graham, Alicia E., Ellis, Tom“…Using synthetic biology tools, we engineer Sender and Receiver strains of K. rhaeticus to produce and respond to the diffusible signalling molecule, acyl‐homoserine lactone. We demonstrate that communication can occur both within and between growing pellicles and use this in a boundary detection experiment, where spliced and joined pellicles sense and reveal their original boundary. …”
Publicado 2018
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7411“…Other important bioactives, such as phenolic acids and lactones, are derived from microbial metabolism. The identification of the metabolites produced after cocoa intake is a first step to understand the overall effect on human health. …”
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7412“…The ability of this monomer to copolymerize with other commercially available acrylates is studied using emulsion polymerization techniques. The pendent lactone ring remains unopened during polymerization and the new monomer is able to copolymerize with other acrylates such as methyl methacrylate and styrene. …”
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7413por Zhao, Guanyi, Han, Qi, Peng, Xiang, Zou, Pengyi, Wang, Haidong, Du, Changping, Wang, He, Tong, Xiaojun, Li, Qiong, Guo, Hong“…Commonly, based on the Tolles–Lawson model, this issue is solved as a linear regression problem. …”
Publicado 2019
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7414por Almandil, Noor Barak, Taha, Muhammad, Gollapalli, Mohammed, Rahim, Fazal, Ibrahim, Mohamed, Mosaddik, Ashik, Anouar, El Hassane“…All compounds showed outstanding β-glucuronidase activity with IC(50) values ranging between 0.5 ± 0.08 to 38.9 ± 0.8 µM when compared with standard d-saccharic acid 1,4 lactone (IC(50) value of 48.1 ± 1.2 µM). The compound 6, a 2,3-dihydroxy analog was found the most potent among the series with IC(50) value 0.5 ± 0.08 µM. …”
Publicado 2019
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7415por Frey, Maximilian, Klaiber, Iris, Conrad, Jürgen, Bersch, Aylin, Pateraki, Irini, Ro, Dae-Kyun, Spring, Otmar“…Sesquiterpene lactones (STL) are a subclass of isoprenoids with many known bioactivities frequently found in the Asteraceae family. …”
Publicado 2019
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7416“…In regression analyses, 6 serum and 28 urine metabolites were significantly associated with change in RSS. Urine gluconic acid lactone was the most significantly correlated with clinical response (correlational coefficient 0.915). …”
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7417por Aslanli, Aysel, Stepanov, Nikolay, Razheva, Tatyana, Podorozhko, Elena A., Lyagin, Ilya, Lozinsky, Vladimir I., Efremenko, Elena“…His(6)-OPH possesses lactonase activity, with a number of N-acyl homoserine lactones being the inducers of Gram-negative bacterial resistance. …”
Publicado 2019
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7418“…This may be related to higher levels of glucose and l‐galactono‐1, 4‐lactone dehydrogenase activity seen in the treated group versus the control. …”
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7419por Yin, Jun-Jun, He, Yan, An, Jun, Miao, Qiang, Sui, Ruo-Xuan, Wang, Qing, Yu, Jie-Zhong, Xiao, Bao-Guo, Ma, Cun-Gen“…Ginkgolide B (GB), a major terpene lactone and active component of Ginkgo biloba, has neuroprotective effects in several models of neurological diseases. …”
Publicado 2020
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7420por Chen, Yu-Hsin, Huang, Kuan-Ying A., Huang, Yi-Chuan, Chi, Hsin, Lu, Chun-Yi, Chang, Luan-Yin, Ho, Yu-Huai, Chi, Chia-Yu, Liu, Ching-Chuan, Huang, Li-Min, Yang, Tien Yu Owen, Huang, Yhu-Chering“…Three ST59 MRSA isolates carried the Panton-Valentine Leukocidin genes. CONCLUSIONS: The results indicated a high prevalence of S. arueus and MRSA nasal colonization among pediatric ICU patients in Taiwan. …”
Publicado 2020
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