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  1. 7421
    “…The worldwide spread of the third pandemic began when the plague reached Hong Kong and Canton in the year 1894. The gram-negative coccobacillus now designated as Yersinia pestis has been discovered as the causative agent of plague in this Hong Kong outbreak. …”
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    The history of the plague and the research on the causative agent Yersinia pestis
  2. 7422
    “…The obtained value for pH (3.58–4.08), free acidity (30.9–36.0 meq/kg), lactone acidity (9.0–14.3 meq/kg), total acidity (42.1–46.0 meq/kg), moisture content (19.1–20.0%), diastase activity (8.11–12.7 ºG), colour intensity (41.5–86.6 mm Pfund), hydroxymethylfurfural (15.7–26.0 mg/kg), and electrical conductivity (0.33–0.52 mS/cm) were within the criteria set by international quality regulations. …”
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    Sensory Profile and Physico-Chemical Properties of Artisanal Honey from Zulia, Venezuela
  3. 7423
    “…[Image: see text] Positional order in the lyotropic chromonic liquid crystals (LCLCs) is investigated in the supramolecular assembly of benzene 1,3,5-tricarboxamide (BTA) derivatives with the glucono-delta-lactone (GdL) acid additive by high-resolution synchrotron radiation small-angle X-ray scattering. …”
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    Positional Order in the Columnar Phase of Lyotropic Chromonic Liquid Crystals Mediated by Ionic Additives
  4. 7424
    “…Although LuxR-N-acyl homoserine lactone systems have been characterized in Gram-negative bacteria, we revealed LuxR-β-carboline system in Streptomyces sp. …”
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    β-carboline chemical signals induce reveromycin production through a LuxR family regulator in Streptomyces sp. SN-593
  5. 7425
    “…The purpose of our study was to explore whether deoxyelephantopin (DET), a sesquiterpene lactone, has a potential antitumor effect in pancreatic cancer. …”
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    Deoxyelephantopin induces apoptosis via oxidative stress and enhances gemcitabine sensitivity in vitro and in vivo through targeting the NF-κB signaling pathway in pancreatic cancer
  6. 7426
    “…The main volatile components in the SDE extract were benzyl alcohol, linalool, hotrienol, geraniol, α-terpineol, coumarin, camphene, benzeneacetaldehyde, 2-hexanone, cis-jasmin lactone and phenylethyl alcohol. GC-MS-O and aroma reconstruction experiments showed 16 aroma-active compounds. …”
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    Characterization of the Aroma of an Instant White Tea Dried by Freeze Drying
  7. 7427
    por Poddighe, Dimitri, Aljofan, Mohamad
    Publicado 2020
    “…Macrolides are a large group of antibiotics characterised by the presence of a macro-lactone ring of variable size. The prototype of macrolide antibiotics, erythromycin was first produced by Streptomyces and associated species more than half a century ago; other related drugs were developed. …”
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    Clinical evidences on the antiviral properties of macrolide antibiotics in the COVID-19 era and beyond
  8. 7428
    “…In this paper, we integrate 13 years of weekly malaria surveillance data collected at the district level in Peru and the canton level in Ecuador, and leverage hierarchical Bayesian spatiotemporal regression models to identify the degree to which malaria transmission in Ecuador is influenced by transmission in Peru. …”
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    Malaria Transmission and Spillover across the Peru–Ecuador Border: A Spatiotemporal Analysis
  9. 7429
    “…However, results of lanolin alcohols, epoxy resin, and Sesquiterpene lactone mix varied significantly with season. Atopy was significantly associated with 18.8% of positive reactions in winter and only with 5.2% of positive reactions in summer (p = 0.015). …”
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    Seasonal Variation in Patch Test Results with European Baseline Series
  10. 7430
    “…To date, 152 chemical constituents have been identified and characterized from the genus Bergenia that belong to the chemical classes of polyphenols, phenolic-glycosides, lactones, quinones, sterols, tannins, terpenes, and others. …”
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    Bergenia Genus: Traditional Uses, Phytochemistry and Pharmacology
  11. 7431
    “…Enzymes hydrolyzing N-acyl homoserine lactones (AHLs) and peptides that are signal molecules of Gram-negative and Gram-positive bacterial cells, respectively, were estimated as “partners” for antibiotics and antimicrobial peptides in newly designed antimicrobial–enzymatic combinations. …”
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    Bacterial Cellulose Containing Combinations of Antimicrobial Peptides with Various QQ Enzymes as a Prototype of an “Enhanced Antibacterial” Dressing: In Silico and In Vitro Data
  12. 7432
    “…They formed biofilms and produced acyl-homoserine lactones (AHLs), which are involved in the quorum sensing regulation process. …”
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    Analysis of the Interaction between Pisum sativum L. and Rhizobium laguerreae Strains Nodulating This Legume in Northwest Spain
  13. 7433
    “…Antaroide is a nine-membered macrolide with lactone and lactam moieties. To investigate its applicability in skin whitening cosmetics, its anti-melanogenic activity in B16F10 murine melanoma cells was examined. …”
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    Antaroide, a Novel Natural Nine-Membered Macrolide, Inhibits Melanin Biosynthesis in B16F10 Murine Melanoma Cells
  14. 7434
    “…Xanthatin (Xa) is a bicyclic sesquiterpene lactone identified from the plant Xanthium L. with impressive antitumor activity, but the role of Xa in non‐small cell lung cancer (NSCLC) is not known. …”
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    Xanthatin synergizes with cisplatin to suppress homologous recombination through JAK2/STAT4/BARD1 axis in human NSCLC cells
  15. 7435
    “…It has been proven to be a feasible source of biologically relevant elements (K, Fe, Ca), vitamins (A, B(1), B(2), C) as well as bioactive compounds (inulin, sesquiterpene lactones, coumarin derivatives, cichoric acid, phenolic acids), which exert potent pro-health effects on the human organism. …”
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    The Common Cichory (Cichorium intybus L.) as a Source of Extracts with Health-Promoting Properties—A Review
  16. 7436
    “…G. biloba dry extract is specified to contain at least 24% flavonol glycosides, at least 6% terpene lactones and less than 5 ppm ginkgolic acids. Since uncertainty remains concerning the nature of up to 75% of the extract, the additive is not sufficiently characterised to allow an assessment based on the individual components. …”
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    Safety and efficacy of a feed additive consisting of a dried extract from the leaves of Ginkgo biloba L. (G. biloba dry extract) for use in cats and dogs (C.I.A.M.)
  17. 7437
    “…Additionally, this review identifies major processes (lactonization, P-gp contribution, ATS-Ca solubility, simultaneous management of multiple analytes, and experimental evidence in the target population), which would enhance the PBPK model prediction to serve as a valid tool for ATS dose optimization.…”
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    Current Evidence, Challenges, and Opportunities of Physiologically Based Pharmacokinetic Models of Atorvastatin for Decision Making
  18. 7438
    “…A new series of carbohydrate-based macrocycles containing triazole and lactone moieties have been designed and synthesized. …”
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    Synthesis of Carbohydrate Based Macrolactones and Their Applications as Receptors for Ion Recognition and Catalysis
  19. 7439
    “…We studied the metabolization of taraxinic acid β-D-glucopyranosyl ester (TA-G), a sesquiterpene lactone of the common dandelion (Taraxacum officinale) that deters its major root herbivore, the common cockchafer larva (Melolontha melolontha). …”
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    A beta-glucosidase of an insect herbivore determines both toxicity and deterrence of a dandelion defense metabolite
  20. 7440
    “…Density-functional theory (DFT) computations were used to explain the reaction mechanism for the ring opening of the epoxide and the formation of five-membered lactones. The stereochemistry of the synthesized compounds was determined by 1D and 2D NMR spectroscopy. …”
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    Efficient and regioselective synthesis of dihydroxy-substituted 2-aminocyclooctane-1-carboxylic acid and its bicyclic derivatives
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