“…We used the developed framework to generate predictions for the spread of COVID-19 in the canton of Geneva, Switzerland, and validated them by comparing the calculated number of cases and recoveries with data from local seroprevalence studies.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…DNA sequencing revealed several transposon insertions clustered in gene regions associated with lipopolysaccharide (LPSI and LPSII), and N-acyl-homoserine lactone synthesis (quorum sensing). Twelve transposon insertions were located within transcriptional regulators or intergenic regions. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In this study, duo-induction methods of laccase and glucono-δ-lactone (L&GDL) or laccase and transglutaminase (L&MTG) were used to prepare the soy protein isolate-sugar beet pectin (SPI-SBP) emulsion gel. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In D. solani motility is regulated by ExpI-ExpR proteins, homologous to luxI-luxR system from Vibrio fisheri, in which N-acyl-homoserine lactones (AHLs) serve as signaling molecules. Moreover, in many Gram-negative bacteria motility is coupled with central metabolism via carbon catabolite repression. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In this study, we were interested in three molecules or classes of molecules present in chicory root: fructose, chlorogenic acids, and sesquiterpene lactones. We conducted experiments on the murine model and performed a nutrigenomic analysis, a metabolic hormone assay and a gut microbiota analysis, associated with in vitro observations for different responses. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Today, cardoon is recognized as a plant with great industrial potential and is considered as a functional food, with important nutritional value, being an interesting source of bioactive compounds, such as phenolics, minerals, inulin, fiber, and sesquiterpene lactones. These bioactive compounds have been vastly described in the literature, exhibiting a wide range of beneficial effects, such as antimicrobial, anti-inflammatory, anticancer, antioxidant, lipid-lowering, cytotoxic, antidiabetic, antihemorrhoidal, cardiotonic, and choleretic activity. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Outstandingly, nicansteroidins A and B possess an unusual side chain with an exocyclic double bond on the δ-lactone system, whereas nicansteroidins C and D have an uncommon cycloperoxide functionality in ring A as distinct structural motifs. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The risk maps showed high suitability for Ae. albopictus establishment in the Central Plateau, the area of Basel, and the lower Rhone Valley in the Canton of Valais. Conclusions: The areas identified as suitable for Ae. albopictus establishment are consistent with the actual current findings of tiger mosquito. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This study evaluated the performance of MADByTE for compound dereplication by examining two classes of fungal metabolites, the resorcylic acid lactones (RALs) and spirobisnaphthalenes. First, a pure compound database was created using the HSQC and TOCSY data from 19 RALs and 10 spirobisnaphthalenes. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Due to its chemical properties and multiple molecular effects on different tumor cell types, the sesquiterpene lactone parthenolide (PN) can be considered an effective drug with significant potential in cancer therapy. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Deoxyelephantopin and isodeoxyelephantopin, sesquiterpene lactone compounds, are major components of Elephantopus scaber and Elephantopus carolinianus, which have long been used as traditional medicines to treat multiple ailments, including liver diseases, diabetes, bronchitis, fever, diarrhea, dysentery, cancer, renal disorders, and inflammation-associated diseases. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Moreover, the high selectivity and high sensitivity of EDPC towards ClO(−) are attributed to the oxidation reaction between the C–O of the coumarin lactone and the C[double bond, length as m-dash]C formed by aldol condensation and the mechanism was further verified using ESI-MS and DFT. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…A series of natural polyaromatic compounds have previously displayed the capability to bind lithium via polar oxygen-containing functional groups that act as redox centers in potential electrodes. Lawsone, a widely renowned dye molecule extracted from the henna leaf, can be dimerized to bislawsone to yield up to six carbonyl/hydroxyl groups for potential lithium coordination. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Versiquinazoline L bearing a d-Ala residue and versiquinazoline M containing an l-serine residue are rarely found in the fumiquinazoline-type alkaloids, while versiquinazoline P displayed an unusual scaffold with a spiro-γ-lactone. Versiquinazolines P and Q exhibited significant inhibition against thioredoxin reductase (TrxR) with IC(50) values of 13.6 ± 0.6 and 12.2 ± 0.7 μM, which showed higher activity than the positive control curcumin (IC(50) = 25 μM). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…A total of 70 volatiles were identified, with lactones, alcohols and esters representing the main classes of apricot volatiles accounting for its discrete aroma. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CTS are commonly referred to cardiac glycosides (CGs) which are composed of sugar residues, unsaturated lactone rings and steroid cores. Their traditional mechanism of action is to inhibit sodium-potassium ATPase to strengthen the heart and regulate heart rate, so it is currently widely used in the treatment of cardiovascular diseases such as heart failure and tachyarrhythmia. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The percentages obtained for ashes were (0.13–0.69%), electrical conductivity (0.36–1.35 mS/cm), water content (17.30–22.80%), pH (4.17–5.05), free acidity (11.0–42.50 meq/kg), lactone acidity (4.0–16.50 meq/kg), and for total acidity (16.50–59.50 meq/kg). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Here, an electrospinning scaffold based on deferoxamine and poly(3(S)-methyl-morpholine-2,5-dione-co-lactone) (PDPLA/DFO) was constructed. This work aims to explore the promotion of nerve regeneration by the physiological regulation of the scaffold. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…A preliminary phytochemical analysis was performed, detecting the presence of saponins, tannins, cardiotonic glycosides, and sesquiterpene lactones. The presence of nicotinic acid in F. echidne and F. latispinus was identified by GC-MS. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This method was successfully applied to three different commercial liquors and led to the identification of 188 flavor compounds, including alcohols, esters, lactones, carbonyls, acetals, fatty acids, phenols, furans, aromatics, terpenoids, alkenes, and alkanes.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso