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  1. 7601
    “…Isoalantolactone (IATL), an isomeric sesquiterpene lactone isolated from the plant of inula helenium, has been reported to have anti-cancer activity against a variety of cancer cells. …”
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    Isoalantolactone Enhances the Antitumor Activity of Doxorubicin by Inducing Reactive Oxygen Species and DNA Damage
  2. 7602
    “…The critical combinations of alginate, calcium carbonate and d-glucono-δ-lactone (GDL) combined with the scaffold production parameters (extrusion time, temperature, and curing time) were evaluated and discussed. …”
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    Alginate Self-Crosslinking Ink for 3D Extrusion-Based Cryoprinting and Application for Epirubicin-HCl Delivery on MCF-7 Cells
  3. 7603
    “…Artemisinin is a natural bioactive sesquiterpene lactone containing an unusual endoperoxide 1, 2, 4-trioxane ring. …”
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    Artemisinins in Combating Viral Infections Like SARS-CoV-2, Inflammation and Cancers and Options to Meet Increased Global Demand
  4. 7604
    “…The anti-QS potential of HA was evaluated by β-galactosidase assay and acylated homoserine lactones (AHL) analysis. The MIC of HA was > 1.20 mM. …”
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    Quorum Sensing Inhibition and Metabolic Intervention of 4-Hydroxycinnamic Acid Against Agrobacterium tumefaciens
  5. 7605
    “…The model has been verified against measured energy data from a total number of 451 buildings in three urban neighborhoods in the Canton of Geneva, Switzerland. The accuracy of the engineering model in predicting the energy demand has been improved by 10%, in terms of the mean absolute percentage error, as a result of adopting a data-driven correction with a random forest algorithm. …”
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    Impact of the COVID-19 pandemic on the energy performance of residential neighborhoods and their occupancy behavior
  6. 7606
    “…Muriolide (MO) is a natural lactone that was isolated from Ranunculus muricatus. …”
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    The radical scavenging activity of muriolide in physiological environments: mechanistic and kinetic insights into double processes
  7. 7607
    “…This plant is a rich source of secondary metabolites (SMs) such as coumarins, flavonoids, benzenoids, lactones, tannins, phenols, and sterols, which make this plant a highly valued medicinal herb with a broad spectrum of pharmacological activities such as anti-urolithic, antioxidant, anti-viral, free radical scavenging, antidiabetic, anti-hepatotoxic, diuretic, antipyretic, anti-oxaluria, anti-tumour, antibacterial, antifungal, anti-inflammatory, antimicrobial, and cardioprotective. …”
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    Bergenia pacumbis (Buch.-Ham. ex D.Don) C.Y.Wu & J.T.Pan: A Comprehensive Review on Traditional Uses, Phytochemistry and Pharmacology
  8. 7608
    por Reveilhac, Maud
    Publicado 2022
    “…These actors are scientists (experts), policymakers (government officials, cantonal executives, and other parties), and representatives of mass media. …”
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    The deployment of social media by political authorities and health experts to enhance public information during the COVID-19 pandemic
  9. 7609
    “…Compound 1 was a novel degraded carbon diterpene with the disappearing of methyl signal at C-19, while compound 7 possessed a new norabietane-type diterpenoid carbon skeleton with the presence of five-membered lactone arising from ring rearrangement. The anti-inflammatory of all obtained isolates were evaluated on lipopolysaccharide (LPS)-stimulated RAW 264.7 cells and the results of anti-inflammatory activity screening showed that compared with the LPS model group, all compounds were significantly down-regulation the TNF-α inflammatory factor at the specific concentration, except for compound 6.…”
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    Abietane-Type Diterpenoids From Nepeta bracteata Benth. and Their Anti-Inflammatory Activity
  10. 7610
    “…The alignment between federal policies and cantonal specificities also appears as necessary to achieve involvement of professionals, promote integration of services and coordination of professionals for continuous and efficient care.…”
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    Healthcare stakeholders' perspective on barriers to integrated care in Switzerland: Results from the open‐ended question of a nationwide survey
  11. 7611
    “…Oxovitisins are a unique group of anthocyanin derivatives with a non-oxonium nature and α-pyranone (lactone) D ring on the structure. In this study, oxovitisin A was synthesized through the micro-oxidative reaction of carboxypyranomalvidin-3-O-glucoside (vitisin A) with water, and its thermostability, pH, and SO(2) color stability were studied compared with its two precursors, malvidin-3-O-glucoside (Mv3glc) and vitisin A, as well as methylpyrano-malvidin-3-O-glucoside (Me-py). …”
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    Stability and Antiproliferative Activity of Malvidin-Based Non-Oxonium Derivative (Oxovitisin A) Compared with Precursor Anthocyanins and Pyranoanthocyanins
  12. 7612
    “…The concentrations of esters, lactones, and acids were significantly higher in the pervaporation produced peach spirit than those in the distilled peach spirit, while terpenoids showed opposite tendency. …”
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    Characterization of Key Aroma-Active Compounds in Two Types of Peach Spirits Produced by Distillation and Pervaporation by Means of the Sensomics Approach
  13. 7613
    “…Four different reducing agents (ascorbic acid, a starter culture, sodium ascorbate and glucono-delta-lactone) were added to the meat batter to assess their impact on the physico-chemical traits, instrumental color, residual nitrates and nitrites and lipid oxidation of this meat product. …”
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    Influence of Common Reducing Agents on Technological Parameters of Dry-Fermented Sausages with Low Fat Content
  14. 7614
    “…Autoinducers, for example, acyl-homoserine lactones (AHLs), auto-inducing oligo-peptides (AIPs) and autoinducer 2, present in both Gram-negative and Gram-positive bacteria, with their mechanism, are also explained. …”
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    Exploring the Function of Quorum Sensing Regulated Biofilms in Biological Wastewater Treatment: A Review
  15. 7615
    “…Ivermectin (IVM), an antiparasitic macrocyclic lactone, was tested and confirmed for its in vitro antiviral activity against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) in early 2020. …”
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    Repurposing Potential of the Antiparasitic Agent Ivermectin for the Treatment and/or Prophylaxis of COVID-19
  16. 7616
    “…Baeyer–Villiger monooxygenases, which oxidize ketones to lactones using aerial oxygen, among other activities, suffer particularly from these instabilities. …”
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    Mutations Increasing Cofactor Affinity, Improve Stability and Activity of a Baeyer–Villiger Monooxygenase
  17. 7617
    “…Artemisia ssp. primarily contain sesquiterpenoid lactones, coumarins, flavonoids, and phenolic acids. …”
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    Artemisia Species with High Biological Values as a Potential Source of Medicinal and Cosmetic Raw Materials
  18. 7618
    por Dicks, Leon M. T.
    Publicado 2022
    “…Signals produced by bacteria are diverse and include autoinducers (AIs), homoserine lactones (HSLs), quinolines, peptides, toxins and proteases. …”
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    How does Quorum Sensing of Intestinal Bacteria Affect Our Health and Mental Status?
  19. 7619
    por Emmenegger, Marc, De Cecco, Elena, Lamparter, David, Jacquat, Raphaël P.B., Riou, Julien, Menges, Dominik, Ballouz, Tala, Ebner, Daniel, Schneider, Matthias M., Morales, Itzel Condado, Doğançay, Berre, Guo, Jingjing, Wiedmer, Anne, Domange, Julie, Imeri, Marigona, Moos, Rita, Zografou, Chryssa, Batkitar, Leyla, Madrigal, Lidia, Schneider, Dezirae, Trevisan, Chiara, Gonzalez-Guerra, Andres, Carrella, Alessandra, Dubach, Irina L., Xu, Catherine K., Meisl, Georg, Kosmoliaptsis, Vasilis, Malinauskas, Tomas, Burgess-Brown, Nicola, Owens, Ray, Hatch, Stephanie, Mongkolsapaya, Juthathip, Screaton, Gavin R., Schubert, Katharina, Huck, John D., Liu, Feimei, Pojer, Florence, Lau, Kelvin, Hacker, David, Probst-Müller, Elsbeth, Cervia, Carlo, Nilsson, Jakob, Boyman, Onur, Saleh, Lanja, Spanaus, Katharina, von Eckardstein, Arnold, Schaer, Dominik J., Ban, Nenad, Tsai, Ching-Ju, Marino, Jacopo, Schertler, Gebhard F.X., Ebert, Nadine, Thiel, Volker, Gottschalk, Jochen, Frey, Beat M., Reimann, Regina R., Hornemann, Simone, Ring, Aaron M., Knowles, Tuomas P.J., Puhan, Milo A., Althaus, Christian L., Xenarios, Ioannis, Stuart, David I., Aguzzi, Adriano
    Publicado 2023
    “…We used TRABI for continuous seromonitoring of hospital patients and blood donors (n = 72′250) in the canton of Zurich from December 2019 to December 2020 (pre-vaccine period). …”
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    Continuous population-level monitoring of SARS-CoV-2 seroprevalence in a large European metropolitan region
  20. 7620
    “…The development of parasites resistant to macrocyclic lactones (ML) has created a significant challenge to the control of the infection. …”
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    A rodent model for Dirofilaria immitis, canine heartworm: parasite growth, development, and drug sensitivity in NSG mice
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