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  1. 7721
    “…Strategies to control LF rely heavily on mass administration of anthelmintic drugs including ivermectin (IVM), a macrocyclic lactone drug considered an Essential Medicine by the WHO. …”
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    Ivermectin inhibits extracellular vesicle secretion from parasitic nematodes
  2. 7722
    “…METHODS/DESIGN: We conducted a qualitative study with 22 individuals aged 45 to 86 and resident in the Canton of Ticino (Switzerland). Participants had previously joined the validation phase of an epidemiological study into dementia and its impact. …”
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    Returning individual‐specific results of a dementia prevalence study: insights from prospective participants living in Switzerland
  3. 7723
    “…We attribute likely extract activity to the presence of sesquiterpene lactones, in combination with other components like steroids and flavonoids.…”
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    Chemical Composition, Antioxidant and Anticancer Activities of Leptocarpha rivularis DC Flower Extracts
  4. 7724
    por Stucki, Michael
    Publicado 2021
    “…The aim of this paper is to decompose inpatient care costs in the Swiss canton of Zurich by 100 diseases and 42 age/sex groups and to assess the contribution of six factors to the change in aggregate costs between 2013 and 2017. …”
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    Factors related to the change in Swiss inpatient costs by disease: a 6-factor decomposition
  5. 7725
    “…The strong bioactivity potential of the aforementioned strains was also evident in the abundance of BGCs, which encoded mainly beta-lactones, bacteriocins, non-ribosomal peptide synthetases (NRPS), terpenes, and siderophores. …”
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    Bioactivity Screening and Gene-Trait Matching across Marine Sponge-Associated Bacteria
  6. 7726
    “…They are classified into polyketides, terpenoids, steroids, macrolides, ten-membered lactones, alkaloids, flavonoids, and fatty acids. Polyketides constitute the main chemical population, accounting for 64%. …”
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    Bioactive Secondary Metabolites of the Genus Diaporthe and Anamorph Phomopsis from Terrestrial and Marine Habitats and Endophytes: 2010–2019
  7. 7727
    “…On the contrary, terpenes, lactones, and C(13) norisoprenoids showed lower variations in oral aroma release over time, thus showing a higher oral aroma persistence. …”
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    Oral Release Behavior of Wine Aroma Compounds by Using In-Mouth Headspace Sorptive Extraction (HSSE) Method
  8. 7728
    por Mayencourt, Gil, Quin, Grégory
    Publicado 2021
    “…Finally, a last part widens the perspective by highlighting, on one side, the cultural, political, and cantonal constraints on national expansion through youth of Swiss gymnastics and, on the other side, how these constraints have generated unifying and patriotic ambitions and discourses within the SFG.…”
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    From Mandatory School Gymnastics to Physical Training for Youth. How the Société Fédérale de Gymnastique Became a “Gymnastic State” Dedicated to the Physical Preparation of Swiss Youth From 1873 to 1907
  9. 7729
    “…γ-Butyrolactone, a five-membered lactone moiety, is one of the privileged structures of diverse natural products and biologically active small molecules. …”
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    A Review of the Pharmacological Activities and Recent Synthetic Advances of γ-Butyrolactones
  10. 7730
    “…An investigation was conducted in the Vaud Canton of Switzerland, where milk-based products are sprayed by helicopter over vineyards. …”
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    Skimmed Milk Applied as a Phytopharmaceutical Product: A Risk for Allergic Populations?
  11. 7731
    “…In order to verify performance in a real clinical setting, we silently deployed a preliminary version of the deep neural network at New York University Langone Health during the first wave of the pandemic, which produced accurate predictions in real-time. …”
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    An artificial intelligence system for predicting the deterioration of COVID-19 patients in the emergency department
  12. 7732
    “…Jerusalem isolates from seven different poultry productions distributed over six cantons in Switzerland were reported, providing further evidence of a possible outbreak. …”
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    Feedborne Salmonella enterica Serovar Jerusalem Outbreak in Different Organic Poultry Flocks in Switzerland and Italy Linked to Soya Expeller
  13. 7733
    por Fujii, Junichi
    Publicado 2021
    “…The last step in the biosynthesis of ascorbate is catalyzed by l-gulono-γ-lactone oxidase whose gene Gulo is commonly mutated in all animals that do not synthesize ascorbate. …”
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    Ascorbate is a multifunctional micronutrient whose synthesis is lacking in primates
  14. 7734
    “…Many bacteria communicate with kin and coordinate group behaviors through a form of cell-cell signaling called acyl-homoserine lactone (AHL) quorum sensing (QS). In these systems, a signal synthase produces an AHL to which its paired receptor selectively responds. …”
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    A covariation analysis reveals elements of selectivity in quorum sensing systems
  15. 7735
    “…Signaling molecules were characterized as long chain (C(14)) N-acyl-homoserine lactones. The role of the Qsd quorum-quenching pathway in biofilm alteration was confirmed with an R. erythropolis mutant unable to produce the QsdA lactonase, and by expression of the qsdA gene in a heterologous host, Escherichia coli. …”
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    Biocontrol of Biofilm Formation: Jamming of Sessile-Associated Rhizobial Communication by Rhodococcal Quorum-Quenching
  16. 7736
    “…In one case PCR assay for detection of Panton-Valentine leukocidin was performed with positive result. …”
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    L´ostéomyélite aiguë à Staphylocoque aureus résistant à la méthicilline d´origine communautaire chez l´enfant: à propos de 15 cas
  17. 7737
    “…In addition, the lungs of l-gulono-γ-lactone oxidase knockout (GULO-KO) mice also displayed a marked decrease in these genes compared to wild-type controls. …”
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    Vitamin C Enhances Antiviral Functions of Lung Epithelial Cells
  18. 7738
    “…Following our previous studies on the molecular level structure of (co)oligoesters obtained via anionic homo- and co-polymerization of novel β-substituted β-lactones, prepared by the atmospheric pressure carbonylation reaction of respective epoxides, the boric acid biocatalyzed ring-opening (co)polymerization of δ-valerolactone has been studied. …”
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    Towards Advances in Molecular Understanding of Boric Acid Biocatalyzed Ring-Opening (Co)Polymerization of δ-Valerolactone in the Presence of Ethylene Glycol as an Initiator
  19. 7739
    “…Then, two of the PCET reagents are applied in representative oxidative aryl‐aryl coupling reactions, namely the intramolecular coupling of 3,3’’‐4,4’’‐tetramethoxy‐o‐terphenyl to give the corresponding triphenylene, the intermolecular coupling of N‐ethylcarbazole to give N,N’‐diethyl‐3,3’‐bicarbazole, and in the oxidative lactonization of 2‐[(4‐methoxyphenyl)methyl]‐benzoic acid. …”
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    Proton‐Coupled Electron Transfer (PCET) with 1,4‐Bisguanidino‐Benzene Derivatives: Comparative Study and Use in Acid‐Initiated C‐H Activation
  20. 7740
    “…Interestingly, molecular dynamic simulations showed that both fatty acids bind to the quorum sensing acyl homoserine lactone synthase (AbaI), and decent conformational stabilities of interactions between the fatty acids and AbaI were exhibited. …”
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    Assessment of Antibiofilm Potencies of Nervonic and Oleic Acid against Acinetobacter baumannii Using In Vitro and Computational Approaches
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