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7881“…We further show that roseobacticide production is quorum sensing regulated via an N-acyl homoserine lactone signal (3-OH–C(10)-HSL). To ensure tight regulation of algaecide production, and thus of a lifestyle switch from mutualism to parasitism, roseobacticide biosynthesis necessitates the presence of both an algal senescence molecule and a quorum sensing signal.…”
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7882“…Aldehydes and terpenes decreased significantly during the whole development period, whereas lactones and apocarotenoids significantly increased with fruit ripening. …”
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7883por Maisuria, Vimal B., Los Santos, Yossef Lopez-de, Tufenkji, Nathalie, Déziel, Eric“…Bacteria have evolved multiple strategies for causing infections that include producing virulence factors, undertaking motility, developing biofilms, and invading host cells. N-acylhomoserine lactone (AHL)-mediated quorum sensing (QS) tightly regulates the expression of multiple virulence factors in the opportunistic pathogenic bacterium Pseudomonas aeruginosa. …”
Publicado 2016
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7884por Kimyon, Önder, Ulutürk, Zehra İ., Nizalapur, Shashidhar, Lee, Matthew, Kutty, Samuel K., Beckmann, Sabrina, Kumar, Naresh, Manefield, Mike“…Some bacteria use N-acyl-L-homoserine lactone (AHL) mediated quorum sensing (QS) to regulate chitinase production in order to catalyze the cleavage of chitin polymers into water soluble N-acetyl-D-glucosamine (NAG) monomers. …”
Publicado 2016
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7885“…The majority of sea cucumber triterpene glycosides are of the holostane type containing a C18 (20) lactone group and either Δ(7(8)) or Δ(9(11)) double bond in their genins. …”
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7886por Purg, Miha, Pabis, Anna, Baier, Florian, Tokuriki, Nobuhiko, Jackson, Colin, Kamerlin, Shina Caroline Lynn“…Methyl parathion hydrolase (MPH) is an enzyme from the metallo-β-lactamase superfamily, which hydrolyses a wide range of organophosphate, aryl ester and lactone substrates. In addition, MPH demonstrates metal-ion-dependent selectivity patterns. …”
Publicado 2016
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7887por Rémy, Benjamin, Plener, Laure, Poirier, Laetitia, Elias, Mikael, Daudé, David, Chabrière, Eric“…This enzyme is a lactonase catalyzing the hydrolysis of acyl-homoserine lactones; these molecules are involved in Gram-negative bacterial communication referred to as quorum sensing. …”
Publicado 2016
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7888por Yuan, Yue, Wen, Jian, Tang, Jie, Kan, Qiming, Ackermann, Rose, Olsen, Karl, Schwendeman, Anna“…Partitioning of HCPT in the sHDL lipid membrane enhanced drug stability in its active lactone form, increased solubilization, and enabled slow release. …”
Publicado 2016
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7889por Mao, Jin, He, Bing, Zhang, Liangxiao, Li, Peiwu, Zhang, Qi, Ding, Xiaoxia, Zhang, Wen“…The high-resolution mass spectra reflected that two main products were formed after the modification of a double bond in the terminal furan ring and the fracture of the lactone ring, while the small molecules especially nitrogen-containing compound may have participated in the photochemical reaction. …”
Publicado 2016
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7890“…The aims of the current study focus on identifying AI-1 type QS signals, i.e., acyl homoserine lactones (AHLs), in Kandelia obovata rhizosphere environment. …”
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7891“…INTRODUCTION: The objective of this study was to determine the oral health condition Down syndrome (DS) children in Bosnia and Herzegovina, by analizing oral health of Down syndrome individuals in two largest regions, Sarajevo and Tuzla Canton. PATIENTS AND METHODS: Caries and oral health status of Down syndrome children aged 6-18 years were examined and assessed according WHO 1997 criteria. …”
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7892por Vavricka, Stephan, Ruiz, Pedro A, Scharl, Sylvie, Biedermann, Luc, Scharl, Michael, de Vallière, Cheryl, Lundby, Carsten, Wenger, Roland H, Held, Leonhard, Merz, Tobias M, Gassmann, Max, Lutz, Thomas, Kunz, Andres, Bron, Denis, Fontana, Adriano, Strauss, Laura, Weber, Achim, Fried, Michael, Rogler, Gerhard, Zeitz, Jonas“…ETHICS AND DISSEMINATION: The study protocol was approved by the Ethics Committee of the Kanton Zurich (reference KEK-ZH-number 2013-0284). …”
Publicado 2017
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7893por Clamens, Thomas, Rosay, Thibaut, Crépin, Alexandre, Grandjean, Teddy, Kentache, Takfarinas, Hardouin, Julie, Bortolotti, Perrine, Neidig, Anke, Mooij, Marlies, Hillion, Mélanie, Vieillard, Julien, Cosette, Pascal, Overhage, Joerg, O’Gara, Fergal, Bouffartigues, Emeline, Dufour, Alain, Chevalier, Sylvie, Guery, Benoit, Cornelis, Pierre, Feuilloley, Marc G. J., Lesouhaitier, Olivier“…In the same line, AmiE is involved in P. aeruginosa motilities (swarming and twitching) and production of the quorum sensing molecules N-acyl homoserine lactones and Pseudomonas Quinolone Signal (PQS). We observed that AmiE overproduction reduced levels of HCN and pyocyanin causing a decreased virulence in different hosts (i.e. …”
Publicado 2017
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7894por Liu, Weifeng, Wang, Xinshuai, Sun, Junjun, Yang, Yanhui, Li, Wensheng, Song, Junxin“…Parthenolide, a sesquiterpene lactone isolated from feverfew, has exhibited potent anticancer effects against various cancers. …”
Publicado 2017
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7895por Li, Mingyue, Song, Li-Hua, Yue, Grace Gar-Lee, Lee, Julia Kin-Ming, Zhao, Li-Mei, Li, Lin, Zhou, Xunian, Tsui, Stephen Kwok-Wing, Ng, Simon Siu-Man, Fung, Kwok-Pui, Tan, Ning-Hua, Lau, Clara Bik-San“…Bigelovin, a sesquiterpene lactone isolated from Inula helianthus aquatica, has been proven to induce apoptosis and exhibit anti-inflammatory and anti-angiogenic activities. …”
Publicado 2017
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7896“…Moreover, rpoA gene silencing resulted in suppression of its message as well as reduced expression of two important methicillin-resistant S. aureus USA300 toxins (α-hemolysin and Panton-Valentine leukocidin). This study confirms that rpoA gene is a potential target for development of novel antisense therapeutics to treat infections caused by methicillin-resistant S. aureus.…”
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7897“…Many potential prey of M. xanthus communicate amongst themselves using acyl homoserine lactones (AHLs) as quorum signals. M. xanthus cannot itself produce AHLs, but could potentially benefit by responding to exogenous AHLs produced during signaling between proximal prey. …”
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7898por Ceccoli, Romina D., Bianchi, Dario A., Fink, Michael J., Mihovilovic, Marko D., Rial, Daniela V.“…Baeyer–Villiger monooxygenases are recognized by their ability and high selectivity as oxidative biocatalysts for the generation of esters or lactones using ketones as starting materials. These enzymes represent valuable tools for biooxidative syntheses since they can catalyze reactions that otherwise involve strong oxidative reagents. …”
Publicado 2017
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7899“…They assist bacteria in perceiving acyl homoserine lactones (AHLs) and/or non-AHLs signaling molecules for establishing intraspecies, interspecies, and interkingdom communication. …”
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7900por Ruffing, Ulla, Alabi, Abraham, Kazimoto, Theckla, Vubil, Delfino C., Akulenko, Ruslan, Abdulla, Salim, Alonso, Pedro, Bischoff, Markus, Germann, Anja, Grobusch, Martin P., Helms, Volkhard, Hoffmann, Jonas, Kern, Winfried V., Kremsner, Peter G., Mandomando, Inacio, Mellmann, Alexander, Peters, Georg, Schaumburg, Frieder, Schubert, Sabine, Strauß, Lena, Tanner, Marcel, Briesen, Hagen von, Wende, Laura, Müller, Lutz von, Herrmann, Mathias“…Significant differences between African versus German isolates were found for alleles encoding the accessory gene regulator type, enterotoxins, the Panton-Valentine leukocidin, immune evasion gene cluster, and adhesins. …”
Publicado 2017
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