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  1. 8141
    por Bailly, Christian, Vergoten, Gérard
    Publicado 2023
    “…The main camptothecin structural elements implicated in the ribosomal protein interaction are the lactone moiety, the aromatic system and the 10-hydroxyl group. …”
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    Interaction of Camptothecin Anticancer Drugs with Ribosomal Proteins L15 and L11: A Molecular Docking Study
  2. 8142
    “…Upon interaction with NEMs, only the epidemic MRSA strains expressed pore-forming toxins, including alpha-hemolysin (Hla), gamma-hemolysin (HlgB), Panton-Valentine leucocidin (LukS) and LukED. Together, these data indicate that the outcome of the interaction between MRSA and human skin mimics, depends on the unique combination of bacterial strain and host factors.…”
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    The survival of epidemic and sporadic MRSA on human skin mimics is determined by both host and bacterial factors
  3. 8143
    “…A total of 20 participants (37 eyes) who were 18 or older and had glaucoma or were glaucoma suspects were enrolled from the NYU Langone Eye Center and Bellevue Hospital. During their usual ophthalmology visit, they were consented for the study and underwent 360-degree goniophotography using the NIDEK Gonioscope GS-1. …”
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    Automated 360-degree goniophotography with the NIDEK Gonioscope GS-1 for glaucoma
  4. 8144
    “…Andrographolide (AG), a diterpenoid lactone, is widely recognized as a natural anticancer drug due to its ability to inhibit cancer growth. …”
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    Andrographolide suppresses aerobic glycolysis and induces apoptotic cell death by inhibiting pyruvate dehydrogenase kinase 1 expression
  5. 8145
    por Alcaraz, J, Alvisi, D, Alpat, B, Ambrosi, G, Anderhub, H, Ao, L, Arefev, A, Azzarello, P, Babucci, E, Baldini, L, Basile, M, Barancourt, D, Barão, F, Barbier, G, Barreira, G, Battiston, R, Becker, R, Becker, U, Bellagamba, L, Béné, P, Berdugo, J, Berges, P, Bertucci, B, Biland, A, Bizzaglia, S, Blasko, S, Bölla, G, Boschini, M, Bourquin, Maurice, Bruni, G, Buénerd, M, Burger, J D, Burger, W J, Cai, X D, Cavalletti, R, Camps, C, Cannarsa, P, Capell, M, Casadei, D, Casaus, J, Castellini, G, Chang, Y H, Chen, H F, Chen, H S, Chen, Z G, Chernoplekov, N A, Chiarini, A, Tzi Hong Chiueh, Chuang, Y L, Cindolo, F, Commichau, V, Contin, A, Cotta-Ramusino, A, Crespo, P, Cristinziani, M, Da Cunha, J P, Dai, T S, Deus, J D, Dinu, N, Djambazov, L, D'Antone, I, Dong, Z R, Emonet, P, Engelberg, J, Eppling, F J, Eronen, T, Esposito, G, Extermann, Pierre, Favier, Jean, Feng, C C, Fiandrini, E, Finelli, F, Fisher, P H, Flaminio, R, Flügge, G, Fouque, N, Galaktionov, Yu, Gervasi, M, Giusti, P, Grandi, D, Gu, W Q, Hangarter, K, Hasan, A, Hermel, V, Hofer, H, Huang, M A, Hungerford, W, Ionica, M, Ionica, R, Jongmanns, M, Karlamaa, K, Karpinski, W, Kenney, G, Kenny, J, Kim, W, Klimentov, A, Kossakowski, R, Koutsenko, V F, Laborie, G, Laitinen, T, Lamanna, G, Laurenti, G, Lebedev, A, Lee, S C, Levi, G, Levchenko, P M, Liu, C L, Liu Hong Tao, Lolli, M, Lopes, I, Lu, G, Lü, Y S, Lübelsmeyer, K, Luckey, D, Lustermann, W, Maña, C, Margotti, A, Massera, F, Mayet, F, McNeil, R R, Meillon, B, Menichelli, M, Mezzanotte, F, Mezzenga, R, Mihul, A, Molinari, G, Mourão, A M, Mujunen, A, Palmonari, F, Pancaldi, G, Papi, A, Park, I H, Pauluzzi, M, Pauss, Felicitas, Perrin, E, Pesci, A, Pevsner, A, Pilastrini, R, Pimenta, M, Plyaskin, V, Pozhidaev, V, Postema, H, Postolache, V, Prati, E, Produit, N, Rancoita, P G, Rapin, D, Raupach, F, Recupero, S, Ren, D, Ren, Z, Ribordy, M, Richeux, J P, Riihonen, E, Ritakari, J, Röser, U, Roissin, C, Sagdeev, R, Santos, D, Sartorelli, G, Schultz von Dratzig, A, Schwering, G, Seo, E S, Shoutko, V, Shoumilov, E, Siedling, R, Son, D, Song, T, Steuer, M, Sun, G S, Suter, H, Tang, X W, Ting, Samuel C C, Ting, S M, Tornikoski, M, Torromeo, G, Torsti, J, Trümper, J E, Ulbricht, J, Urpo, S, Usoskin, I, Valtonen, E, Van den Hirtz, J, Velcea, F, Velikhov, E P, Verlaat, B, Vetlitskii, I, Vezzu, F, Vialle, J P, Viertel, Gert M, Vitè, Davide F, Von Gunten, H P, Waldmeier-Wicki, S, Wallraff, W, Wang, B C, Wang, J Z, Wang, Y H, Wiik, K, Williams, C, Wu, S X, Xia, P C, Yan, J L, Yan Lu Guang, Yang, C G, Yang, M, Ye Shu Wei, Yeh, P, Xu, Z Z, Zhang, H Y, Zhang, Z P, Zhao, D X, Zhu, G Y, Zhu, W Z, Zhuang, H L, Zichichi, A
    Publicado 2000
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    Protons in near earth orbit
  6. 8146
    por Ewings, P., Bowie, C.
    Publicado 1996
    “…A total of 159 cases, diagnosed at Taunton. Yeovil and Exeter hospitals between May 1989 and May 1991, were identified prospectively and interviewed with a structured questionnaire. …”
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    A case-control study of cancer of the prostate in Somerset and east Devon.
  7. 8147
    “…Our study reveals that KpG phages has the potential to curtail plantonic and biofilm mode of growth in higher animal models.…”
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    Phages from Ganges River curtail in vitro biofilms and planktonic growth of drug resistant Klebsiella pneumoniae in a zebrafish infection model
  8. 8148
    “…In this report, we demonstrate that the degradation intermediate of PHB effectively inhibits biofilm formation, luminescence, motility behaviour, haemolysin production and the N-acyl-homoserine lactone (AHL)-mediated quorum-sensing pathway in PUGSK8. …”
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    Degradation intermediates of polyhydroxy butyrate inhibits phenotypic expression of virulence factors and biofilm formation in luminescent Vibrio sp. PUGSK8
  9. 8149
    por Chasalow, Fred I
    Publicado 2021
    “…SS are phosphocholine esters of steroids with a lactone E-ring, similar to that of spironolactone. …”
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    Spiral Steroids During Pregnancy - It’s All About Potassium
  10. 8150
    por Solís, Salvador
    Publicado 2014
    “…En 2006 recibió el Premio de Artes, Letras y Ciencias de la República y Cantón de Jura. En 2009 fue invitado por la Facultad de Teatro de la Universidad Veracruzana para realizar el montaje Nada de nada, basado en una novela corta del escritor suizo Peter Bischsel. …”
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    Filosofía, teatro y comunidad: Diálogo con Germain Meyer
  11. 8151
    “…Results showed that soymilk added with Glucono-Delta-Lactone (GDL) coagulated at the temperature above 60 °C, and the loss factor (ε″) was slightly reduced when soymilk was converted to tofu at coagulation temperature. …”
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    Developing radio frequency (RF) heating protocol in packed tofu processing by computer simulation
  12. 8152
    “…RESULTS: A total of 12 G6PD mutations were identified. Canton (c.1376G>T) and Kaiping (c.1388G>A) were the most common variants, and different mutations led to varying levels of G6PD enzyme activity. …”
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    Genotypic and phenotypic characterization of glucose-6-phosphate dehydrogenase (G6PD) deficiency in Guangzhou, China
  13. 8153
    “…As a potential drug candidate for the treatment of hypertension and complications, it is speculated that the component-based Chinese medicine of Ginkgo biloba leaves (GBCCM) which mainly composed of flavonoid aglycones (FAs) and terpene lactones (TLs) may have different pharmacological effects at different doses or ratios. …”
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    Pharmacological activities and effective substances of the component-based Chinese medicine of Ginkgo biloba leaves based on serum pharmacochemistry, metabonomics and network pharmacology
  14. 8154
    por Breijyeh, Zeinab, Karaman, Rafik
    Publicado 2023
    “…Additionally, drug repurposing (such as with ticagrelor, mitomycin C, auranofin, pentamidine, and zidovudine) and synthesis of novel antibacterial agents (including lactones, piperidinol, sugar-based bactericides, isoxazole, carbazole, pyrimidine, and pyrazole derivatives) represent novel approaches to treating infectious diseases. …”
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    Design and Synthesis of Novel Antimicrobial Agents
  15. 8155
    “…Staphylococcus aureus causes severe infections such as pneumonia and sepsis depending on the pore-forming toxin Panton–Valentine leukocidin (PVL). PVL kills and induces inflammation in macrophages and other myeloid cells by interacting with the human cell surface receptor, complement 5a receptor 1 (C5aR1). …”
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    FBXO11 governs macrophage cell death and inflammation in response to bacterial toxins
  16. 8156
    “…Parthenolide (PTL) is a sesquiterpene lactone derived from feverfew with various therapeutic benefits. …”
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    Parthenolide Phytosomes Attenuated Gentamicin-Induced Nephrotoxicity in Rats via Activation of Sirt-1, Nrf2, OH-1, and NQO1 Axis
  17. 8157
    “…In addition to these proteinogenic amino acids, the excreted carbon consisted of homoserine lactone, homoserine and an unidentified amino acid. …”
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    “Candidatus Hydrogenisulfobacillus filiaventi” strain R50 gen. nov. sp. nov., a highly efficient producer of extracellular organic compounds from H(2) and CO(2)
  18. 8158
    “…The inhibitory activity could be related to alkaloids, lactones, quinones, flavonoids, triterpenes, and sterols, as indicated by chemical screening and antifungal compounds, such as widdrol, β-caryophyllene, tyrosol, butyl isobutyrate, sorbic acid, palmitic acid, palmitelaidic acid, linoleic acid, and oleic acid, which were identified by gas chromatography–mass spectrometry (GC-MS). …”
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    Chemical Characterization of Trichoderma spp. Extracts with Antifungal Activity against Cocoa Pathogens
  19. 8159
    “…A01A‐347 revealed sulfur‐ and nitrogen‐containing compounds, ketones, alcohols, aldehydes, aromatic compounds, amides and one lactone, as well as the typical algal products, apocarotenoids. …”
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    Volatiles of the Apicomplexan Alga Chromera velia and Associated Bacteria
  20. 8160
    “…Methods: In this observational study, all patients hospitalized due to COVID-19 in 2020 in the Cantonal Hospital of Baden were included. We assessed clinical characteristics, in-hospital outcomes as well as long-term outcomes with a mean follow-up time of 278 (±90) days. …”
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    Long-Term Mortality after New-Onset Atrial Fibrillation in COVID-19
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