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  1. 8361
    “…Their extracts were previously shown to contain quorum sensing (QS) signal molecules of the N-acyl homoserine lactone (AHL) type, known to orchestrate bacterial gene regulation. …”
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    Identification of Quorum Sensing Activators and Inhibitors in The Marine Sponge Sarcotragus spinosulus
  2. 8362
    “…Conformationally unrestricted spacer between the lactone and 1,2,3-triazole units in 8a−8u series had a profound effect on antitumor activity. …”
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    Antitumor and antiviral activities of 4-substituted 1,2,3-triazolyl-2,3-dibenzyl-L-ascorbic acid derivatives
  3. 8363
    “…Brefeldin A (BFA), a unique fungal metabolite of a 13-membered lactone ring, exhibits various biological actions, including antitumor, antifungal and antiviral activities. …”
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    Brefeldin A inhibits the antiviral action of interferon against encephalomyocarditis virus
  4. 8364
    “…Genes encoding important toxins (Panton-Valentine leukocidins, alpha-haemolysin, protein A) involved in the development of staphylococcal pneumonia were also present in the MSSA genome. …”
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    Atypical Presentation of Methicillin-Susceptible Staphylococcus aureus Infection in a Dengue-Positive Patient: A Case Report with Virulence Genes Analysis
  5. 8365
    “…The process of color matching is infrequently described in the literature. The Pantone SkinTone Guide (PSTG) is a handheld tool comprised of realistic skin tone swatches with a corresponding virtual swatch system. …”
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    Establishing a Clinically Applicable Methodology for Skin Color Matching in Vascularized Composite Allotransplantation
  6. 8366
    “…Costunolide being a sesquiterpene lactone, is known to have anticancer properties. The present study investigated the anticancer effects of costunolide against the H1299 human non-small-cell lung cancer (NSCLC) cell line. …”
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    Costunolide induces apoptosis and inhibits migration and invasion in H1299 lung cancer cells
  7. 8367
    “…Andrographolide (AG), a major diterpene lactone isolated from Andrographis paniculata (Burm. f.) …”
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    Oral Bioavailability Enhancement and Anti-Fatigue Assessment of the Andrographolide Loaded Solid Dispersion
  8. 8368
    “…The activity of human paraoxonase 2 (PON2) is rapidly reduced in cells incubated with the bacterial quorormone 3-Oxo-dodecanoyl Homoserine Lactone (3OC12HSL), an observation that led to hypothesize a fast PON2 post-translational modification (PTM). …”
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    WTAP and BIRC3 are involved in the posttranscriptional mechanisms that impact on the expression and activity of the human lactonase PON2
  9. 8369
    “…This rare invasive infection was due to Panton-Valentine Leucocidin-producing (PVL+) methicillin-susceptible Staphylococcus aureus (MSSA). …”
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    Spontaneous community-acquired PVL-producing Staphylococcus aureus mediastinitis in an immunocompetent adult – a case report
  10. 8370
    “…Especially, coumarin, dehydrocostus lactone, atractylenolide II, and atractylenolide I were exclusively found in CSF from the Guangdong province; isopsoralen was almost exclusively found in CSF from the Guangxi province; and ferulic acid was exclusively found in CSF from the Zhejiang province. …”
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    UPLC-Q-Exactive Orbitrap MS Analysis for Identification of Lipophilic Components in Citri Sarcodactylis Fructus from Different Origins in China Using Supercritical CO(2) Fluid Extraction Method
  11. 8371
    “…Here we report on the specific action of eight different individual QS signals (acyl-homoserine lactones; AHLs varying in acyl-chain length from four to 14 carbon atoms) on prophage induction in soil microbial communities. …”
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    Quorum Sensing Signals Alter in vitro Soil Virus Abundance and Bacterial Community Composition
  12. 8372
    “…Key steps in the synthesis of F-TxA(2) included α-fluorination of a lactone bearing a β-alkoxy group, and a novel synthesis of the strained acetal. …”
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    Synthesis, Stability, and Biological Studies of Fluorinated Analogues of Thromboxane A(2)
  13. 8373
    “…LukS-PV is the S component of Panton-Valetine leukocidin (PVL), which is secreted by Staphylococcus aureus. …”
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    LukS-PV Inhibits Hepatocellular Carcinoma Progression by Downregulating HDAC2 Expression
  14. 8374
    “…The quorum sensing (QS) signaling molecule, N-(3-oxododecanoyl)-L-homoserine lactone (3O-C12-HSL), contributes to the pathogenesis of Pseudomonas aeruginosa by regulating expression of the bacterial virulence factors that cause intense inflammation and toxicity in the infected host. …”
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    Human Single-chain Variable Fragments Neutralize Pseudomonas aeruginosa Quorum Sensing Molecule, 3O-C12-HSL, and Prevent Cells From the HSL-mediated Apoptosis
  15. 8375
    “…Data were collected from 403 students in the Swiss canton of Bern and 387 students in Luxembourg who participated in three waves of the “School Alienation in Switzerland and Luxembourg (SASAL)” research project. …”
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    School alienation and academic achievement in Switzerland and Luxembourg: a longitudinal perspective
  16. 8376
    “…Costunolide (CTL) is a natural sesquiterpene lactone with wide pharmacological activities including anti-inflammation and antioxidation. …”
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    Costunolide Plays an Anti-Neuroinflammation Role in Lipopolysaccharide-Induced BV2 Microglial Activation by Targeting Cyclin-Dependent Kinase 2
  17. 8377
    “…OBJECTIVE: We discuss the psychosocial implications of the COVID-19 pandemic as self-reported by housestaff and faculty in the NYU Langone Health Department of Neurology, and summarize how our program is responding to these ongoing challenges. …”
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    The psychosocial implications of COVID-19 for a neurology program in a pandemic epicenter
  18. 8378
    “…Chicory roots consist of a mixture of inulin, pectin, and (hemi-)cellulose and also contain complex phytochemicals, such as sesquiterpene lactones that have been characterized in detail. Nowaday, chicory roots are mainly applied as a source for the extraction of inulin, which is used as prebiotic fiber and food ingredient. …”
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    Back to the Roots: Revisiting the Use of the Fiber-Rich Cichorium intybus L. Taproots
  19. 8379
    “…Plants also evolved to perceive and respond to those molecules. N-acyl homoserine lactones (AHL) are QS molecules, of which impact has been extensively studied in different plants. …”
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    Impact of Quorum Sensing Molecules on Plant Growth and Immune System
  20. 8380
    “…BACKGROUND: Costunolide (COS), a naturally occurring sesquiterpene lactone, is known to exert anti‐inflammatory, antioxidant, and anticancer effects. …”
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    Costunolide promotes the proliferation of human hair follicle dermal papilla cells and induces hair growth in C57BL/6 mice
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