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901por Chan, Kok-Gan, Sulaiman, Joanita, Yong, Delicia Ann, Tee, Kok Keng, Yin, Wai-Fong, Priya, Kumutha“…Staphylococcus saprophyticus strain SU8 was isolated from a pristine water source in Malaysia and it exhibited degradation of N-hexanoylhomoserine lactone. Here we report the draft genome sequence of S. saprophyticus strain SU8 to further understand its quorum quenching abilities.…”
Publicado 2015
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902“…l-Galactono-1,4-lactone dehydrogenase (GLDH) catalyses the last enzymatic step of the ascorbate biosynthetic pathway in plants. …”
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903por Torres, Marta, Rubio-Portillo, Esther, Antón, Josefa, Ramos-Esplá, Alfonso A., Quesada, Emilia, Llamas, Inmaculada“…In this study, we present the screening of QQ activity amongst 450 strains isolated from a bivalve hatchery in Granada (Spain), and the selection of the strain PQQ-42, which degrades a wide range of N-acylhomoserine lactones (AHLs). The selected strain, identified as Alteromonas stellipolaris, degraded the accumulation of AHLs and reduced the production of protease and chitinase and swimming motility of a Vibrio species in co-cultivation experiments in vitro. …”
Publicado 2016
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905por Hodille, Elisabeth, Cuerq, Charlotte, Badiou, Cédric, Bienvenu, Françoise, Steghens, Jean-Paul, Cartier, Régine, Bes, Michèle, Tristan, Anne, Plesa, Adriana, Le, Vien T. M., Diep, Binh A., Lina, Gérard, Dumitrescu, Oana“…Here, we show that delta-hemolysin (Hld) and phenol soluble modulins (PSMs) PSMα1 and PSMα3, but not alpha-hemolysin (Hla) or Panton-Valentine leukocidin (PVL), induce dose-dependent tryptase, and lactate dehydrogenase (LDH) release by the HMC-1 human mast cell line. …”
Publicado 2016
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906
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907“…The viability of this scenario for intramolecular C–H insertion reactions affording β-lactones via Rh-carbenoid intermediates is assessed through quantum chemical calculations on potential energy surfaces and quasi-classical molecular dynamics simulations. …”
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908“…Pironetin is a natural product with potent antiproliferative activity that forms a covalent adduct with α‐tubulin via conjugate addition into the natural product's α,β‐unsaturated lactone. Although pironetin's α,β‐unsaturated lactone is involved in its binding to tubulin, the structure–activity relationship at different positions of the lactone have not been thoroughly evaluated. …”
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909por Doberva, Margot, Stien, Didier, Sorres, Jonathan, Hue, Nathalie, Sanchez-Ferandin, Sophie, Eparvier, Véronique, Ferandin, Yoan, Lebaron, Philippe, Lami, Raphaël“…Quorum sensing (QS) is a density-dependent mechanism allowing bacteria to synchronize their physiological activities, mediated by a wide range of signaling molecules including N-acyl-homoserine lactones (AHLs). Production of AHL has been identified in various marine strains of Proteobacteria. …”
Publicado 2017
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910por Jepsen, Tue Heesgaard, Glibstrup, Emil, Crestey, François, Jensen, Anders A, Kristensen, Jesper Langgaard“…We report an effective synthetic protocol to access [6,6]-bicyclic lactone moieties through a regio- and stereoselective intramolecular Mizoroki–Heck cross-coupling reaction followed by a 6π-electrocyclization. …”
Publicado 2017
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911por Havaei, Seyed Asghar, Poursina, Farkhondeh, Ahmadpour, Maryam, Havaei, Seyed Roholla, Ruzbahani, Meisam“…BACKGROUND: Panton-Valentine leukocidin (PVL) is a gamma-toxin produced by Staphylococcus aureus encoded by genes lukS/lukF-PV with several single-nucleotide polymorphisms. …”
Publicado 2017
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912“…OBJECTIVE: This study was undertaken to determine the frequency of Panton-Valentine leukocidin (PVL)-producing Staphylococcus aureus among strains isolated in our laboratory and to study the association of PVL-positive strains with clinical disease. …”
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913por Ulloa, Jerónimo L., Spina, Renata, Casasco, Agustina, Petray, Patricia B., Martino, Virginia, Sosa, Miguel A., Frank, Fernanda M., Muschietti, Liliana V.“…In this study, we evaluated the activity of enhydrin, uvedalin and polymatin B, three sesquiterpene lactones (STLs) isolated from Smallanthus sonchifolius, on Leishmania mexicana (MNYC/BZ/62/M) and Trypanosoma cruzi (Dm28c). …”
Publicado 2017
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914por Leistner, Rasmus, Kola, Axel, Gastmeier, Petra, Krüger, Renate, Hoppe, Pia-Alice, Schneider-Burrus, Sylke, Zuschneid, Irina, Wischnewski, Nicoletta, Bender, Jennifer, Layer, Franziska, Niebank, Michaela, Scheibenbogen, Carmen, Hanitsch, Leif G.“…METHODS: The transmission route was investigated by nasal screening for Panton-Valentine leukocidin (PVL)-producing Staphylococcus aureus (PVL-SA), subsequent microbiological investigation including whole genome sequencing and a questionnaire-based analysis of epidemiological information. …”
Publicado 2017
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915“…Lactone 2a of a bicyclo[4.3.0]nonane structure is a good starting material for synthesis of many attractive compounds. …”
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916por Peng, Huasong, Ouyang, Yi, Bilal, Muhammad, Wang, Wei, Hu, Hongbo, Zhang, Xuehong“…Phenazine production is regulated by a quorum sensing (QS) system that involves the N-acylated homoserine lactones (AHLs)—a prevalent type of QS molecule. RESULTS: Three QS signals were detected by thin layer chromatography (TLC) and high-performance liquid chromatography–mass spectrometry (HPLC–MS/MS), which identified to be N-(3-hydroxy hexanoyl)-l-homoserine lactone (3-OH-C6-HSL), N-(3-hydroxy octanoyl)-l-homoserine lactone (3-OH-C8-HSL) and N-(3-hydroxy decanoyl)-l-homoserine lactone (3-OH-C10-HSL). …”
Publicado 2018
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917por Softic, Adis, Asmare, Kassahun, Granquist, Erik Georg, Godfroid, Jacques, Fejzic, Nihad, Skjerve, Eystein“…A total of 1970 serum samples were collected from cattle in farms located in three cantons (regions). Enzyme linked immunosorbent assays were used to screen for seropositivity against four selected pathogens. …”
Publicado 2018
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918por Turnbull, Frank, Jonsson, Nicholas N., Kenyon, Fiona, Skuce, Philip J., Bisset, Stewart A.Enlace del recurso
Publicado 2018
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919por Sun, Tingting, Zhang, Lihua, Li, Xinxin, Chen, Fengfei, Li, Yanchuan, Ma, Xiaohui, Yu, Feng“…Aim: To investigate the protective effect of dantonic in ischemic myocardial damage by evaluating the expression of circulating microvesicles (MVs) and microRNA-1 (miR-1) in two animal models. …”
Publicado 2018
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920por Zhao, Mingming, Yu, Yingying, Hua, Yuhui, Feng, Fan, Tong, Yigang, Yang, Xiaohong, Xiao, Junhai, Song, Hongrui“…A novel series of N-sulfonyl homoserine lactone derivatives 5a–l has been designed, synthesized and evaluated for quorum sensing inhibitory activities towards violacein production. …”
Publicado 2013
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