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9601por Kailasan, Shweta, Kant, Ravi, Noonan-Shueh, Madeleine, Kanipakala, Tulasikumari, Liao, Grant, Shulenin, Sergey, Leung, Daisy W., Alm, Richard A., Adhikari, Rajan P., Amarasinghe, Gaya K., Gross, Michael L., Aman, M. Javad“…Here, we isolated two anti-Hla and three anti-Panton-Valentine Leukocidin (LukSF-PV) mAbs, and used a combination of hydrogen deuterium exchange mass spectrometry (HDX-MS) and alanine scanning mutagenesis to delineate and validate the toxins’ epitope landscape. …”
Publicado 2022
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9602por Peluso, Marco, Munnia, Armelle, Russo, Valentina, Galli, Andrea, Pala, Valeria, van der Schouw, Yvonne T., Schulze, Matthias B., Weiderpass, Elisabete, Tumino, Rosario, Saieva, Calogero, Exezarreta Pilar, Amiano, Aune, Dagfinn, Heath, Alicia K., Aglago, Elom, Agudo, Antonio, Panico, Salvatore, Petersen, Kristina Elin Nielsen, Tjønneland, Anne, Cirera, Lluís, Rodriguez-Barranco, Miguel, Katzke, Verena, Kaaks, Rudolf, Ricceri, Fulvio, Milani, Lorenzo, Vineis, Paolo, Sacerdote, Carlotta“…Overall, low cruciferous vegetable intake was correlated with a greater frequency of bulky DNA lesions, including benzo(a)pyrene, lactone and quinone-adducts and bulky oxidative lesions, in the adjusted models. …”
Publicado 2022
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9603por Liu, Lu, Chen, Xian, Jiang, Yifang, Yuan, Yun, Yang, Luyao, Hu, Qiongying, Tang, Jianyuan, Meng, Xianli, Xie, Chunguang, Shen, Xiaofei“…Brevilin A (BVA) is a sesquiterpene lactone from Centipeda minima, a Chinese herb used to treat inflammatory diseases. …”
Publicado 2022
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9604“…Due to the presence of hydroxy fatty acid methyl esters (HFAME) in LFO (∼60%), in addition to producing biofuel it can also be used to generate chemically important estolides and cyclic lactones. AlCl(3), SnCl(2), and Sn(CH(3)COO)(2) showed catalytic activity using direct immersion ultrasound (DI-US) among a list of LA catalysts investigated, with AlCl(3) being the best catalyst. …”
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9605“…Eight isolates carried lukS-PV and lukF-PV that code for Panton-Valentine leukocidin. CONCLUSION: The current CC30-MSSA isolates share phenotypic and genotypic characteristics with the pandemic phage 80/81 isolates that were common in the 1950s and 1960s. …”
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9606por Ngo, Thi Thao, Tran, Thinh Huy, Ta, Thanh Dat, Le, Thi Phuong, Nguyen, Phuoc Dung, Tran, Mai Anh, Bui, The-Hung, Ta, Thanh Van, Tran, Van Khanh“…For G6PD molecular characteristics, Viangchan (c.871G>A), Canton (c.1376G>T) and Kaiping (c.1388G>A) variants were the most dominant, accounting for 24.48%, 17.70%, and 22.42%, respectively, whereas the highest frequency of complex variants was observed in Viangchan/Silent with 20.35%. …”
Publicado 2022
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9607por Ahmed, Asmaa E, Abol-Enein, Hassan, Awadalla, Amira, El degla, Heba, El-Shehaby, Omar A“…Moreover, the adhesion genes (fnbB and can), hemolysine gene (hlb), panton-valentine leukocidin (pvl) gene and the enterotoxin gene (seb) were significantly higher in septic patients compared to the non-septic ones (p< 0.05). …”
Publicado 2022
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9608por Epistolio, Samantha, Ramelli, Giulia, Ottaviano, Margaret, Crupi, Emanuele, Marandino, Laura, Biggiogero, Maira, Maida, Pier Andrea, Ruinelli, Lorenzo, Vogl, Ursula, Mangan, Dylan, Pascale, Mariarosa, Cantù, Marco, Ceschi, Alessandro, Bernasconi, Enos, Mazzucchelli, Luca, Catapano, Carlo, Alimonti, Andrea, Garzoni, Christian, Gillessen Sommer, Silke, Stefanini, Federico Mattia, Franzetti-Pellanda, Alessandra, Frattini, Milo, Pereira Mestre, Ricardo“…Materials and Methods: The cohort included 400 patients hospitalized for COVID-19 during the first wave between February and May 2020 in two different hospitals of Canton Ticino. Genomic DNA was extracted from formalin-fixed paraffin-embedded tissue blocks, and HSD3B1 gene polymorphism was evaluated by Sanger sequencing. …”
Publicado 2022
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9609por Gupta, Snehil, Vohra, Sukhdeep, Sethi, Khushboo, Gupta, Surbhi, Bera, Bidhan Chandra, Kumar, Sanjay, Kumar, Rajender“…With this objective, the macrocyclic lactone representative, ivermectin, has been investigated for the efficacy against T. evansi in the axenic culture medium. …”
Publicado 2022
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9610por Mukhopadhyay, Amrita, Reynolds, Harmony R., Nagler, Arielle R., Phillips, Lawrence M., Horwitz, Leora I., Katz, Stuart D., Blecker, Saul“…METHODS: In this cross-sectional study of all NYU Langone Health outpatients with EF ≤ 40% on echocardiogram and an outpatient visit from 3/1/2019 to 2/29/2020, we assessed prescription of the following therapies: beta-blocker (BB), angiotensin converting enzyme inhibitor (ACE-I)/angiotensin receptor blocker (ARB)/angiotensin receptor neprilysin inhibitor (ARNI), and mineralocorticoid receptor antagonist (MRA). …”
Publicado 2022
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9611por Schwank, Ariane, Struyf, Thomas, Struyf, Filip, Blazey, Paul, Mertens, Michel, Gisi, David, Pisan, Markus, Meeus, Mira“…Ethical approval is granted by the Ethical commission of Canton of Zurich, Switzerland, No: ID_2018-02089 TRIAL REGISTRATION NUMBER: NCT04946149.…”
Publicado 2022
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9612por Frei, Anja, Strassmann, Alexandra, Guler, Mathias, Carron, Tania, Steurer-Stey, Claudia, Lana, Kaba Dalla, Giroud, Philippe, Peytremann-Bridevaux, Isabelle, Puhan, Milo“…To evaluate the effectiveness, we assessed exercise capacity (1-minute sit-to-stand test), disease specific quality of life (Chronic Respiratory Questionnaire CRQ), symptoms, health care utilisation and health behaviour including physical activity at baseline and at the end of the program (after 12 months). RESULTS: Seven Cantonal Lung Associations implemented the program into their services according to plan, conducted it 13 times during 1 year and included in total 122 COPD patients (mean age 69 years, 48% female). …”
Publicado 2022
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9613por Oliveira, Pollianna S., Souza, Simone G., Campos, Guilherme B., da Silva, Danilo C.C., Sousa, Daniel S., Araújo, Suerda P.F., Ferreira, Laiziane P., Santos, Verena M., Amorim, Aline T., Santos, Angelita M.O.G., Timenetsky, Jorge, Cruz, Mariluze P., Yatsuda, Regiane, Marques, Lucas M.“…In addition, we performed PCR for their virulence genes: Sea (enterotoxin A), SEB (B), Sec (C), PVL (Panton-Valentine Leukocidin), ClfA (clumping factor A) and Spa (protein A). …”
Publicado 2013
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9614por Zurita, Jeannete, Barba, Pedro, Ortega-Paredes, David, Mora, Marcelo, Rivadeneira, Sebastián“…Within MRSA, 37 isolates were related to the USA300-LV clone (ST8-MRSA-IV, Panton-Valentine Leukocidin [PVL] +) and 10 were related to the Brazilian clone (ST239-MRSA-III, PVL−). …”
Publicado 2016
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9615por Liang, Hongbao, Sun, Chenghong, Feng, Zhong, Wang, Xianzhen, Kong, Lingpeng, Zhu, Feng, Yao, Jingchun, Yuan, Xiaomei, Liu, Zhong, Zhang, Guimin, Li, Feng“…METHODS: GBCCM mainly containing high pure flavonoid aglycones (FAs) and terpenoid lactones (TLs) was used as the model drug. PVP K30 and SDS were used as solubilizers, combined stabilizers and carriers, and GBCCM NC-SD was prepared by high-pressure homogenization combined with freeze-dryer. …”
Publicado 2022
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9616por Jinling, Dong, Liyuan, Feng, Wenying, Fu, Yuting, Huang, Xiangyu, Tang, Xiuning, Huang, Yu, Tang, Qianliang, Ming, Linming, Guo, Ning, Gao, Peng, Li“…Parthenolide (PTL), a sesquiterpene lactone isolated from shoots of feverfew. Although it has been shown to possess several pharmacological activities and is considered to have potential therapeutic effects on the regeneration of peripheral nerve injury, its efficacy in promoting central nervous system (CNS) regeneration is unclear. …”
Publicado 2022
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9617por Trifan, Adriana, Czerwińska, Monika E., Mardari, Constantin, Zengin, Gokhan, Sinan, Kouadio Ibrahime, Korona-Glowniak, Izabela, Skalicka-Woźniak, Krystyna, Luca, Simon Vlad“…Liquid chromatography with tandem high-resolution mass spectrometry (LC-HRMS/MS) analysis of different polarity extracts obtained from the aerial parts led to the identification of twelve flavonoids, three phenolic acids, two sesquiterpene lactones, two fatty acids, one coumarin, and one lignan. …”
Publicado 2022
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9618por Cotuțiu, Vlad-Dan, Ionică, Angela Monica, Lefkaditis, Menelaos, Cazan, Cristina Daniela, Hașaș, Alina Diana, Mihalca, Andrei Daniel“…The low prevalence rates are probably linked to the wide use of macrocyclic lactones. GRAPHIC ABSTRACT: [Image: see text]…”
Publicado 2022
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9619por Komodromos, Dimitrios, Kotzamanidis, Charalampos, Giantzi, Virginia, Pappa, Styliani, Papa, Anna, Zdragas, Antonios, Angelidis, Apostolos, Sergelidis, Daniel“…The isolated S. aureus strains were examined for their resistance to antimicrobials, carriage of the mecA and mecC genes, carriage of genes encoding for the production of nine staphylococcal enterotoxins, carriage of the Panton–Valentine Leukocidin and Toxic Shock Syndrome genes, and the ability to form biofilm. …”
Publicado 2022
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9620por Matos, Isabelle Faria, Morales, Luis Miguel Mazorra, Santana, Diederson Bortolini, Silva, Gláucia Michelle Cosme, Gomes, Mara Menezes de Assis, Ayub, Ricardo Antônio, Costa, José Hélio, de Oliveira, Jurandi Gonçalves“…This oxidation step is catalyzed by l-galactono-1,4-lactone dehydrogenase (l-GalLDH). This enzyme is not considered a limiting step for AsA production; however, it presents a distinguishing characteristic: the l-GalLDH can introduce electrons directly into the respiratory chain through cytochrome c (Cytc) and therefore can be considered an extramitochondrial electron source that bypasses the phosphorylating Complex III. …”
Publicado 2022
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