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1041por Yin, Panqing, Zhang, Qin, Zhu, Jianming, Wu, Guoqiang, Yin, Sanjun, Ma, Zhenhua, Zhou, Jin“…The thin-layer chromatography analysis showed that three kinds of acyl homoserine lactone (AHL) signals could be produced by S. rhizophila GA1. …”
Publicado 2018
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1042por Kausar, Humera, Smith, Stephen, Qu, Ming Da, Lazar, Peter G, Kroll-Desrosiers, Aimee, Barton, Bruce, Ward, Doyle V, Ellison III, Richard T“…BACKGROUND: The presence of the binary Panton-Valentine Leukocidin (PVL) toxin in Staphylococcus aureus has been associated with both severe pneumonia and skin and soft-tissue infections. …”
Publicado 2018
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1043“…A high-speed counter-current chromatography (HSCCC) method was established for the preparative separation of three sesquiterpenoid lactones from Eupatorium lindleyanum DC. The two-phase solvent system composed of n-hexane–ethyl acetate–methanol–water (1:4:2:3, v/v/v/v) was selected. …”
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1044por Gliszczyńska, Anna, Semba, Damian, Szczepanik, Maryla, Dancewicz, Katarzyna, Gabryś, Beata“…A chemoenzymatic method was applied to obtain optically pure alkyl-substituted δ-lactones. First, chemical Baeyer–Villiger oxidation of dihydrojasmone (1) was carried out, affording two new alkyl-substituted δ-lactones: 3,4-dihydro-5-methyl-6-pentyl-2H-pyran-2-one (2) and 5-methyl-6-pentyl-1,13-dioxabicyclo[4.1.0]heptan-2-one (3). …”
Publicado 2016
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1045por Kusada, Hiroyuki, Zhang, Yu, Tamaki, Hideyuki, Kimura, Nobutada, Kamagata, Yoichi“…N-Acyl homoserine lactones (AHLs) are signaling molecules used in the quorum sensing (QS) of Gram-negative bacteria. …”
Publicado 2019
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1046“…A highly efficient electrochemical reduction of [60]fullerene-fused lactones to [60]fullerene-fused ketones, a formal process of retro Baeyer–Villiger reaction, has been achieved for the first time. …”
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1047“…In this study, bacterial strains were isolated from Saudi Arabian coastal environments and screened for acyl homoserine lactone (AHL)-quenching activities. Five AHL quenching bacterial isolates from the genera Pseudoalteromonas, Pontibacillus, and Altererythrobacter exhibited high AHL-quenching activity at a salinity level of 58 g/L and a pH of 7.8 at 50°C. …”
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1048por Liu, Ling-Pu, Huang, Long-Hui, Ding, Xiao-Tong, Yan, Lin, Jia, Shi-Ru, Dai, Yu-Jie, Xie, Yan-Yan, Zhong, Cheng“…As demonstrated by liquid chromatography-tandem mass spectrometry, Gluconacetobacter xylinus CGMCC No. 2955, a Gram-negative acetic acid-producing bacterium and a typical bacterial cellulose (BC) biosynthesis strain, produces six different AHLs, including N-acetyl-homoserine lactone, N-butanoyl-homoserine lactone, N-hexanoyl-homoserine lactone, N-3-oxo-decanoyl-homoserine lactone, N-dodecanoyl-homoserine lactone, and N-tetradecanoyl-homoserine lactone. …”
Publicado 2019
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1049por Wu, Junkang, Gao, Huan, Ye, Jinyu, Chang, Yan, Yu, Ran, Ding, Zhen, Zhu, Guangcan“…Herein, N-acyl-homoserine lactone (AHL)-based quorum sensing (QS) was investigated for its effects against nano-ZnO toxicity to a model nitrifier, Nitrosomonas europaea. …”
Publicado 2019
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1050por Yu, Yinghua, Chakraborty, Pushkin, Song, Jinshuai, Zhu, Lei, Li, Chunsen, Huang, Xueliang“…Reactions that efficiently construct medium-sized lactones are significant, as they overcome the unfavorable entropic factor and transannular interactions for ring closure, and the lactones produced are common structural motifs recurring in many biologically active compounds. …”
Publicado 2020
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1051por Hanitsch, Leif G., Krüger, Renate, Hoppe, Pia-Alice, Humme, Daniel, Pokrywka, Anna, Niebank, Michaela, Stegemann, Miriam, Kola, Axel, Leistner, Rasmus“…BACKGROUND: Recurrent skin abscesses are often associated with Panton-Valentine leukocidin-producing strains of S. aureus (PVL-SA). …”
Publicado 2020
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1052“…Here, broadband light-harvesting is achieved using two natural pigments, betanin and lawsone, absorbing in the green and blue region of the solar spectrum respectively. …”
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1053“…Various sesquiterpene lactones have been implicated as the cause of poisoning. …”
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1054por Jesudoss Chelladurai, Jeba R. J., Martin, Katy A., Chinchilla-Vargas, Krystal, Jimenez Castro, Pablo D., Kaplan, Ray M., Brewer, Matthew T.“…Prevention of canine heartworm disease caused by Dirofilaria immitis relies on chemoprophylaxis with macrocyclic lactone anthelmintics. Alarmingly, there are increased reports of D. immitis isolates with resistance to macrocyclic lactones and the ability to break through prophylaxis. …”
Publicado 2020
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1055por Yamagishi, Hirofumi, Kawahori, Kenichi, Ohkiba, Noriaki, Murooka, Nozomi, Inazawa, Takeshi“…Whole-genome sequencing and analyses for virulence determinants revealed that, unlike USA300, ksw1 lacked virulence genes, such as Panton-Valentine leukocidin and SCCmec, while harboring the toxic shock syndrome toxin-1 gene. …”
Publicado 2020
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1056“…Excessive production of pro-inflammatory cytokines such as TNF-α plays an important role in the pathological development of OA. Dehydrocostus lactone (DHC) is a kind of sesquiterpene isolated from medicinal plants that has been demonstrated to play a protective role in inflammation and tumor formation. …”
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1057por Fuller, Jacquelyn, Angert, Robert, Fisher, Jason C., Kerns, Rebecca, Jones, Koren, Haines, ElizabethEnlace del recurso
Publicado 2021
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1058por Neganova, Margarita, Semakov, Alexey, Aleksandrova, Yulia, Yandulova, Ekaterina, Pukhov, Sergey, Anikina, Lada, Klochkov, Sergey“…In our work, bipharmacophore molecules containing in their structure a fragment of the known anthracycline antibiotics daunorubicin and doxorubicin and natural sesquiterpene lactones were obtained for the first time. When studying the biological activity of the synthesized compounds, it was found that with equal and, in some cases, higher cytotoxicity and glycolysis inhibition by anthracycline antibiotics conjugates with sesquiterpene lactones in comparison with doxo- and daunorubicin, a reduced damaging effect on the functioning of rat heart mitochondria was observed. …”
Publicado 2021
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1059por Balam, Satheesh Krishna, Soora Harinath, Jayaprakash, Krishnammagari, Suresh Kumar, Gajjala, Raghavendra Reddy, Polireddy, Kishore, Baki, Vijaya Bhaskar, Gu, Wei, Valasani, Koteswara Rao, Avula, Vijaya Kumar Reddy, Vallela, Swetha, Zyryanov, Grigory Vasilievich, Pasupuleti, Visweswara Rao, Cirandur, Suresh ReddyEnlace del recurso
Publicado 2021
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1060por Bazhenov, Sergey, Novoyatlova, Uliana, Scheglova, Ekaterina, Fomin, Vadim, Khrulnova, Svetlana, Melkina, Olga, Chistyakov, Vladimir, Manukhov, Ilya“…Aliivibrio fischeri LuxR and Aliivibrio logei LuxR1 and LuxR2 regulatory proteins are quorum sensing transcriptional (QS) activators, inducing promoters of luxICDABEG genes in the presence of an autoinducer (3-oxo-hexanoyl-l-homoserine lactone). In the Aliivibrio cells, luxR genes are regulated by HNS, CRP, LitR, etc. …”
Publicado 2021
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