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112501“…BACKGROUND: Tryptophan, an essential amino acid found in many protein-based foods, has been involved in the pathogenesis of mood disorders and celiac disease (CeD). …”
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112502por Abdulnoor, Mariana, Eshaghi, AliReza, Perusini, Stephen J., Broukhanski, George, Corbeil, Antoine, Cronin, Kirby, Fittipaldi, Nahuel, Forbes, Jessica D., Guthrie, Jennifer L., Kus, Julianne V., Li, Ye, Majury, Anna, Mallo, Gustavo V., Mazzulli, Tony, Melano, Roberto G., Olsha, Romy, Sullivan, Ashleigh, Tran, Vanessa, Patel, Samir N., Allen, Vanessa G., Gubbay, Jonathan B.“…The N501Y amino acid mutation caused by a single point substitution A23063T in the spike gene of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is possessed by three variants of concern (VOCs), B.1.1.7, B.1.351, and P.1. …”
Publicado 2022
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112503por Chen, Weiguo, Gard, Jamie M. C., Epshtein, Yulia, Camp, Sara M., Garcia, Joe G. N., Jacobson, Jeffrey R., Cress, Anne E.“…We previously reported integrin beta 4 (ITGB4) is an important mediator of lung vascular protection by simvastatin, a 3-hydroxy-3-methylglutaryl-coenzyme A-reductase inhibitor. …”
Publicado 2022
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112504por Takemori, Toshitada, Sugimoto-Ishige, Akiko, Nishitsuji, Hironori, Futamura, Yushi, Harada, Michishige, Kimura-Someya, Tomomi, Matsumoto, Takehisa, Honma, Teruki, Tanaka, Miho, Yaguchi, Masami, Isono, Kyoichi, Koseki, Haruhiko, Osada, Hiroyuki, Miki, Daiki, Saito, Takashi, Tanaka, Takashi, Fukami, Takehiro, Goto, Toshio, Shirouzu, Mikako, Shimotohno, Kunitada, Chayama, Kazuaki“…Among the extracellular loops (ECLs) of NTCP, regions of amino acids (aa) 84 to 87 in ECL1 and aa 157 to 165 near ECL2 of transmembrane domain 5 are critically important for HBV/HDV infection. …”
Publicado 2022
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112505por Song, Baolin, Zeb, Jehan, Hussain, Sabir, Aziz, Muhammad Umair, Circella, Elena, Casalino, Gaia, Camarda, Antonio, Yang, Guan, Buchon, Nicolas, Sparagano, Olivier“…In 18 strains with both sequential and mortality data, amino acid alignment showed several point substitutions that may be related to its virulence. …”
Publicado 2022
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112506por Khan, Mohsin Ali, Singh, Romila, Siddiqui, Sahabjada, Ahmad, Imran, Ahmad, Rumana, Upadhyay, Shivbrat, Barkat, Md. Abul, Ali, Ahmed Mahmoud Abdelhaleem, Zia, Qamar, Srivastava, Aditi, Trivedi, Anchal, Husain, Ishrat, Srivastava, Anand Narain, Mishra, Durga Prasad“…METHODS: In this study, human cancer cell lines were cultured and subsequently treated with 10 to 100 μg/mL of PDSE. …”
Publicado 2022
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112507por Zhang, Ting, Kim, Min Jung, Kim, Min Ju, Wu, Xuangao, Yang, Hye Jeong, Yuan, Heng, Huang, Shaokai, Yoon, Sun Myung, Kim, Keun-Nam, Park, Sunmin“…In metagenome function analysis, PBEH increased the energy metabolism-related pathways of the gut microbiota, including citric acid cycle, oxidative phosphorylation, glycolysis, and amino acid metabolism, which were lower in the MD-control than the Normal-control. …”
Publicado 2022
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112508por Zhang, Yuepeng, Xia, Rongyao, Lv, Meiyu, Li, Zhiheng, Jin, Lingling, Chen, Xueda, Han, Yaqian, Shi, Chunpeng, Jiang, Yanan, Jin, Shoude“…RESULTS: 80 genes were identified via DEG analysis that were primarily involved in cellular amino acid and metabolic processes, regulation of telomerase activity and phagocytosis, antigen processing and MHC class I-mediated peptide antigen presentation, and other biological processes. …”
Publicado 2022
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112509“…MATERIALS AND METHODS: Two ethanolic extracts of Moroccan propolis from the Fez-Meknes region were evaluated regarding the following physicochemical parameters: Yield, pH, total carbohydrates, total proteins, total lipids, minerals, total phenolic content, total flavonoid content, and antioxidant activity using ferric reducing antioxidant power (FRAP) and 2,2’-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assays. …”
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112510por Kumar, Dinesh, Ladaniya, Milind Shivratan, Gurjar, Manju, Kumar, Sunil, Mendke, Sachin“…Antioxidant activity was assessed by three antioxidant assays (ABTS(+) (radical cation azino-bis [3-ethylbenzthiazoline-6-sulfonic acid]) (ABTS), 2,2-diphenyl-1-picrylhydrazyl radical (DPPH), and Ferric Reducing Antioxidant Power (FRAP)). …”
Publicado 2022
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112511“…Recommended treatment is based on an individually tailored resistance exercise training program, the optimization of protein intake using high-quality protein sources (i.e., whey protein) in order to provide a high amount of essential amino acids—particularly leucine—and addressing vitamin D deficiency/insufficiency. …”
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112512“…A GenBank BLAST search of the genomic sequences demonstrated that the OMSV-Ch had the highest identity (74.9%) with the OMSV from Korea (OMSV-Kr). At the amino acid–sequence level, these two strains shared 84.1% identity in putative replication protein (RP) and 94.1% identity in coat protein (CP). …”
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112513por Seabra, Sofia G, Libin, Pieter J K, Theys, Kristof, Zhukova, Anna, Potter, Barney I, Nebenzahl-Guimaraes, Hanna, Gorbalenya, Alexander E, Sidorov, Igor A, Pimentel, Victor, Pingarilho, Marta, de Vasconcelos, Ana T R, Dellicour, Simon, Khouri, Ricardo, Gascuel, Olivier, Vandamme, Anne-Mieke, Baele, Guy, Cuypers, Lize, Abecasis, Ana B“…A total of 50 sites showed evidence of positive selection, and for a few of these sites, there was amino acid (AA) differentiation between genetic clusters. …”
Publicado 2022
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112514por Gao, Dengke, Zhao, Hongcong, Dong, Hao, Li, Yating, Zhang, Jing, Zhang, Haisen, Zhang, Yu, Jiang, Haizhen, Wang, Xiaoyu, Wang, Aihua, Jin, Yaping, Chen, Huatao“…Diurnal changes in clock and clock-controlled gene expression at the mRNA and protein levels were also observed in goat liver and kidney tissues at two representative time points in vivo. Amino acid sequences and tertiary structures of goat BMAL1 and CLOCK proteins were found to be highly homologous to those in mice and humans. …”
Publicado 2022
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112515por Choudhury, Sk Mohiuddin, Ma, XuSheng, Zeng, ZongBo, Luo, Zhikuan, Li, Yuanyuan, Nian, XiaoFeng, Ma, YongHua, Shi, Zhengwang, Song, Rui, Zhu, ZiXiang, Cao, Weijun, Pei, Jingjing, Zheng, HaiXue“…Importantly, we identified that the 1 to 154 amino acid (aa) portion of SVA 3D binds to the NLRP3 NACHT domain to activate NLRP3 inflammasome assembly and IL-1β secretion. …”
Publicado 2022
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112516por Qurrat-ul-Ain, Khurshid, Sumaira, Gul, Zarnab, Khatoon, Jaweria, Shah, Muhammad Raza, Hamid, Irum, Khan, Iffat Abdul Tawab, Aslam, Fariha“…The current study is aimed at synthesizing and characterizing magnetic cobalt–iron oxide nanoparticles (CoFeNPs) functionalized with two different amino reagents, hydrazine and dodecylamine, resulting in CoFeNPs1 and CoFeNPs2, respectively. …”
Publicado 2020
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112517“…METHODS: The pHLIP (Var7) sequence was synthesized via solid-phase peptide synthesis. Four amino acids, Gly-(D)-Ala-Gly-Gly, were attached to the N-terminus of pHLIP (Var7) to form a strong chelating group containing an N4 structure. …”
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112518“…The pet food industry has linked these blemishes, which may be concerning to pet owners, to copper supplementation. …”
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112519por Qi, Qianqian, Xiao, Zhe, Wang, Yaowei, Yan, Xinjin, Fu, Peng, Zhang, Xiaomeng, Zhao, Wei, Pang, Xinchang, Liu, Minying, Zhao, Qingxiang, Cui, Zhe“…In this work, a series of novel silicone-containing polyamides (PA1212/Si12) were successfully synthesized from 1,12-dodecarboxylic acid (LA), 1,12-dodecarbondiamine (DMDA), and 1,3-bis (amino-propyl) tetramethyldisiloxane (BATS), via a one-pot melt polycondensation method in the absence of a catalyst. …”
Publicado 2022
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112520por Wu, Yang, Shi, Huimin, Yu, Haifeng, Ma, Yu, Hu, Haibo, Han, Zhigang, Zhang, Yonghu, Zhen, Zilong, Yi, Liuxi, Hou, Jianhua“…A total of 226 sunflower inbred lines were collected from different regions of China and other countries. …”
Publicado 2022
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