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112641por Poverennaya, Ekaterina V., Pyatnitskiy, Mikhail A., Dolgalev, Georgii V., Arzumanian, Viktoria A., Kiseleva, Olga I., Kurbatov, Ilya Yu., Kurbatov, Leonid K., Vakhrushev, Igor V., Romashin, Daniil D., Kim, Yan S., Ponomarenko, Elena A.“…We demonstrate that TOMM34 affects various processes including oxidative phosphorylation, citric acid cycle, metabolism of purine, and several amino acids. Besides the analysis of already known pathways, we utilized de novo network enrichment algorithm to extract novel perturbed subnetworks, thus obtaining evidence that TOMM34 potentially plays role in several other cellular processes, including NOTCH-, MAPK-, and STAT3-signaling. …”
Publicado 2023
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112642“…The increase in flavor substance content, such as free amino acids, nucleotides, organic acids, and minerals, enhanced the special flavor of the muscle during the simulated live transport. …”
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112643por Yan, Zujie, Yao, Xiaohui, Pan, Ruyi, Zhang, Junjie, Ma, Xiaochun, Dong, Nihua, Wei, Jianchao, Liu, Ke, Qiu, Yafeng, Sealey, Katie, Nichols, Hester, Jarvis, Michael A., Upton, Mathew, Li, Xiangdong, Ma, Zhiyong, Liu, Juxiang, Li, Beibei“…The PstB protein showed nearly 100% amino acid similarity across a panel of 31 S. suis isolates representing different serotypes, which were collected from different countries. …”
Publicado 2023
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112644por Pincus, Matthew R., Lin, Bo, Patel, Purvi, Gabutan, Elmer, Zohar, Nitzan, Bowne, Wilbur B.“…This is a review of approaches to the design of peptides and small molecules that selectively block the oncogenic RAS-p21 protein in ras-induced cancers. Single amino acid substitutions in this protein, at critical positions such as at Gly 12 and Gln 61, cause the protein to become oncogenic. …”
Publicado 2023
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112645por Aworh, Mabel Kamweli, Kwaga, Jacob K. P., Hendriksen, Rene S., Okolocha, Emmanuel C., Harrell, Erin, Thakur, Siddhartha“…Fifteen ciprofloxacin and 19 nalidixic acid-resistant isolates respectively showed double mutations in the quinolone-resistance determining regions (QRDRs) of gyrA, with single or double mutations in parC, and a single mutation in parE. The most prevalent amino-acid substitutions observed were S83L + D87N in gyrA (46.5%, n = 20), S80I in parC (51.2%, n = 22) and S458A in parE (14%, n = 6). …”
Publicado 2023
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112646por Adegbola, Adebanjo J., Ijarotimi, Omotade A., Ubom, Akaninyene E., Adesoji, Bukola A., Babalola, Olajide E., Hocke, Emma F., Hansson, Helle, Mousa, Andria, Bolaji, Oluseye O., Alifrangis, Michael, Roper, Cally“…The Pfdhps gene carried mutations at codons resulting in amino acid changes at 431–436-437–540-581–613; I431V [45.9%, (28/61)], A581G [31.1% (19/61)] and A613S [49.2% (30/61)]. …”
Publicado 2023
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112647por Gupta, Nikhil, Yadav, Deependra Kumar, Gautam, Sonam, Kumar, Ashish, Kumar, Dinesh, Prasad, Narayan“…Compared to CAM-CKD patients, the sera of CKD patients were characterized by (a) elevated levels of urea, creatinine, citrate, glucose, glycerol, and phenylalanine and phenylalanine-to-tyrosine ratio (PTR) and (b) decreased levels of various amino acids (such leucine, isoleucine, valine, and alanine), high-density lipoproteins, lactate, and acetate. …”
Publicado 2023
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112648“…In this study, a cross-sectional serological survey was carried on to estimate the prevalence of Leptospira antibodies in beef cattle in Tandil and Ayacucho Departments (Buenos Aires Province) and to identify risk factors and spatial clusters associated with seropositivity. …”
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112649por Mohan, V, Pinto-Sanchez, M, Nardelli, A, Magee, M, Borojevic, R, De Palma, G, Britz-McKibbin, P, Collins, S, Bercik, P“…Furthermore, during symptom flares, ornithine, citrulline and gluconic acid vary in IBS-D, while amino acids cysteine, methionine, threonine, and glycine vary in IBS-C subjects. …”
Publicado 2023
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112650“…More specifically, fibrostenotic CD is a phenotype with prolonged chronic inflammation and fibrotic strictures often resistant to anti-inflammatory therapies and characterized by luminal narrowing that ultimately requires surgery. …”
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112651por Aaij, R., Adeva, B., Adinolfi, M., Adrover, C., Affolder, A., Ajaltouni, Z., Albrecht, J., Alessio, F., Alexander, M., Alvarez Cartelle, P., Alves Jr, A.A., Amato, S., Amhis, Y., Amoraal, J., Anderson, J., Appleby, R.B., Aquines Gutierrez, O., Arrabito, L., Artuso, M., Aslanides, E., Auriemma, G., Bachmann, S., Bailey, D.S., Balagura, V., Baldini, W., Barlow, R.J., Barschel, C., Barsuk, S., Bates, A., Bauer, C., Bauer, Th., Bay, A., Bediaga, I., Belous, K., Belyaev, I., Ben-Haim, E., Benayoun, M., Bencivenni, G., Bernet, R., Bettler, M.O., van Beuzekom, M., Bifani, S., Bizzeti, A., Bjornstad, P.M., Blake, T., Blanc, F., Blanks, C., Blouw, J., Blusk, S., Bobrov, A., Bocci, V., Bondar, A., Bondar, N., Bonivento, W., Borghi, S., Borgia, A., Bos, E., Bowcock, T.J.V., Bozzi, C., Brambach, T., van den Brand, J., Bressieux, J., Brisbane, S., Britsch, M., Britton, T., Brook, N.H., Brown, H., Buchler-Germann, A., Bursche, A., Buytaert, J., Cadeddu, S., Carvajal, J.M.Caicedo, Callot, O., Calvi, M., Calvo Gomez, M., Camboni, A., Campana, P., Carbone, A., Carboni, G., Cardinale, R., Cardini, A., Carson, L., Akiba, K.Carvalho, Casse, G., Cattaneo, M., Charles, M., Charpentier, Ph., Chiapolini, N., Vidal, X.Cid, Clark, P.J., Clarke, P.E.L., Clemencic, M., Cliff, H.V., Closier, J., Coca, C., Coco, V., Cogan, J., Collins, P., Constantin, F., Conti, G., Contu, A., Coombes, M., Corti, G., Cowan, G.A., Currie, R., D'Almagne, B., D'Ambrosio, C., Da Silva, W., David, P., De Bonis, I., De Capua, S., De Cian, M., De Lorenzi, F., De Miranda, J.M., De Paula, L., De Simone, P., Decamp, D., Degaudenzi, H., Deissenroth, M., Del Buono, L., Deplano, C., Deschamps, O., Dettori, F., Dickens, J., Dijkstra, H., Dima, M., Batista, P.Diniz, Donleavy, S., Dossett, D., Dovbnya, A., Dupertuis, F., Dzhelyadin, R., Eames, C., Easo, S., Egede, U., Egorychev, V., Eidelman, S., van Eijk, D., Eisele, F., Eisenhardt, S., Eklund, L., d'Enterria, D.G., Esperante Pereira, D., Esteve, L., Fanchini, E., Farber, C., Fardell, G., Farinelli, C., Farry, S., Fave, V., Fernandez Albor, V., Ferro-Luzzi, M., Filippov, S., Fitzpatrick, C., Fontanelli, F., Forty, R., Frank, M., Frei, C., Frosini, M., Pazos, J.L.Fungueirino, Furcas, S., Torreira, A.Gallas, Galli, D., Gandelman, M., Gandini, P., Gao, Y., Garnier, J-C., Garofoli, J., Garrido, L., Gaspar, C., Gauvin, N., Gersabeck, M., Gershon, T., Ghez, Ph., Gibson, V., Gligorov, V.V., Gobel, C., Golubkov, D., Golutvin, A., Gomes, A., Gordon, H., Gandara, M.Grabalosa, Graciani Diaz, R., Cardoso, L.A.Granado, Grauges, E., Graziani, G., Grecu, A., Gregson, S., Gui, B., Gushchin, E., Guz, Yu., Gys, T., Haefeli, G., Haines, S.C., Hampson, T., Hansmann-Menzemer, S., Harji, R., Harnew, N., Harrison, P.F., He, J., Hennessy, K., Henrard, P., Morata, J.A.Hernando, van Herwijnen, E., Hicheur, A., Hicks, E., Hofmann, W., Holubyev, K., Hopchev, P., Hulsbergen, W., Hunt, P., Huse, T., Huston, R.S., Hutchcroft, D., Iakovenko, V., Escudero, C.Iglesias, Ilten, P., Imong, J., Jacobsson, R., Hussein, M.Jahjah, Jans, E., Jansen, F., Jaton, P., Jean-Marie, B., Jing, F., John, M., Johnson, D., Jones, C.R., Jost, B., Kapusta, F., Karbach, T.M., Keaveney, J., Kerzel, U., Ketel, T., Keune, A., Khanji, B., Kim, Y.M., Knecht, M., Koblitz, S., Konoplyannikov, A., Koppenburg, P., Kozlinskiy, A., Kravchuk, L., Krocker, G., Krokovny, P., Kruse, F., Kruzelecki, K., Kucharczyk, M., Kukulak, S., Kumar, R., Kvaratskheliya, T., La Thi, V.N., Lacarrere, D., Lafferty, G., Lai, A., Lambert, R.W., Lanfranchi, G., Langenbruch, C., Latham, T., Le Gac, R., van Leerdam, J., Lees, J.P., Lefevre, R., Leflat, A., Lefrancois, J., Leroy, O., Lesiak, T., Li, L., Li, Y.Y., Li Gioi, L., Lieng, M., Liles, M., Lindner, R., Linn, C., Liu, B., Liu, G., Lopes, J.H., Lopez Asamar, E., Lopez-March, N., Luisier, J., M'charek, B., Machefert, F., Machikhiliyan, I.V., Maciuc, F., Maev, O., Magnin, J., Maier, A., Malde, S., Mamunur, R.M.D., Manca, G., Mancinelli, G., Mangiafave, N., Marconi, U., Marki, R., Marks, J., Martellotti, G., Martens, A., Martin, L., Martin Sanchez, A., Martinez Santos, D., Massafferri, A., Mathe, Z., Matteuzzi, C., Matveev, M., Matveev, V., Maurice, E., Maynard, B., Mazurov, A., McGregor, G., McNulty, R., Mclean, C., Meissner, M., Merk, M., Merkel, J., Merkin, M., Messi, R., Miglioranzi, S., Milanes, D.A., Minard, M.N., Monteil, S., Moran, D., Morawski, P., Morris, J.V., Mountain, R., Mous, I., Muheim, F., Muller, K., Muresan, R., Murtas, F., Muryn, B., Musy, M., Mylroie-Smith, J., Naik, P., Nakada, T., Nandakumar, R., Nardulli, J., Nedos, M., Needham, M., Neufeld, N., Nicol, M., Nies, S., Niess, V., Nikitin, N., Oblakowska-Mucha, A., Obraztsov, V., Oggero, S., Okhrimenko, O., Oldeman, R., Orlandea, M., Ostankov, A., Pal, B., Palacios, J., Palutan, M., Panman, J., Papanestis, A., Pappagallo, M., Parkes, C., Parkinson, C.J., Passaleva, G., Patel, G.D., Patel, M., Paterson, S.K., Patrick, G.N., Patrignani, C., Nicorescu, C.Pavel, Pazos Alvarez, A., Pellegrino, A., Penso, G., Altarelli, M.Pepe, Perazzini, S., Perego, D.L., Perez Trigo, E., Yzquierdo, A.Perez-Calero, Perret, P., Petrella, A., Petrolini, A., Valls, B.Pie, Pietrzyk, B., Pinci, D., Plackett, R., Playfer, S., Casasus, M.Plo, Polok, G., Poluektov, A., Polycarpo, E., Popov, D., Popovici, B., Potterat, C., Powell, A., Pree, T.du, Pugatch, V., Puig Navarro, A., Qian, W., Rademacker, J.H., Rakotomiaramanana, B., Raniuk, I., Raven, G., Redford, S., Reece, W., Reis, A.C.dos, Ricciardi, S., Rinnert, K., Romero, D.A.Roa, Robbe, P., Rodrigues, E., Rodrigues, F., Rodriguez Cobo, C., Rodriguez Perez, P., Rogers, G.J., Romanovsky, V., Rouvinet, J., Ruf, T., Ruiz, H., Sabatino, G., Silva, J.J.Saborido, Sagidova, N., Sail, P., Saitta, B., Salzmann, C., Varela, A.Sambade, Sannino, M., Santacesaria, R., Santinelli, R., Santovetti, E., Sapunov, M., Sarti, A., Satriano, C., Satta, A., Savrie, M., Savrina, D., Schaack, P., Schiller, M., Schleich, S., Schmelling, M., Schmidt, B., Schneider, O., Schopper, A., Schune, M.H., Schwemmer, R., Sciubba, A., Seco, M., Semennikov, A., Senderowska, K., Serra, N., Serrano, J., Shao, B., Shapkin, M., Shapoval, I., Shatalov, P., Shcheglov, Y., Shears, T., Shekhtman, L., Shevchenko, O., Shevchenko, V., Shires, A., Simioni, E., Skottowe, H.P., Skwarnicki, T., Smith, A.C., Sobczak, K., Soler, F.J.P., Solomin, A., Somogy, P., Soomro, F., Souza De Paula, B., Spaan, B., Sparkes, A., Spiridenkov, E., Spradlin, P., Stagni, F., Steinkamp, O., Stenyakin, O., Stoica, S., Stone, S., Storaci, B., Straumann, U., Styles, N., Szczekowski, M., Szczypka, P., Szumlak, T., T'Jampens, S., Talanov, V., Teodorescu, E., Terrier, H., Teubert, F., Thomas, C., Thomas, E., van Tilburg, J., Tisserand, V., Tobin, M., Topp-Joergensen, S., Tran, M.T., Tsaregorodtsev, A., Tuning, N., Ukleja, A., Urquijo, P., Uwer, U., Vagnoni, V., Valenti, G., Vazquez Gomez, R., Vazquez Regueiro, P., Vecchi, S., Velthuis, J.J., Veltri, M., Vervink, K., Viaud, B., Videau, I., Vilasis-Cardona, X., Visniakov, J., Vollhardt, A., Voong, D., Vorobyev, A., Vorobyev, An., Voss, H., Wacker, K., Wandernoth, S., Wang, J., Ward, D.R., Webber, A.D., Websdale, D., Whitehead, M., Wiedner, D., Wiggers, L., Wilkinson, G., Williams, M.P., Williams, M., Wilson, F.F., Wishahi, J., Witek, M., Witzeling, W., Wotton, S.A., Wyllie, K., Xie, Y., Xing, F., Yang, Z., Ybeles Smit, G., Young, R., Yushchenko, O., Zavertyaev, M., Zhang, L., Zhang, W.C., Zhang, Y., Zhelezov, A., Zhong, L.“…The analysis is based on a data sample corresponding to an integrated luminosity of 5.2pb-1. The measured cross-sections integrated over the fiducial region are 10.52 +/- 0.04 +/- 1.40 +1.64/-2.20 mub for prompt J/psi production and 1.14 +/- 0.01 +/- 0.16 mub for J/psi from b-hadron decays, where the first uncertainty is statistical and the second systematic. …”
Publicado 2011
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112652por Bunino, Matteo“…</p><h3>Short bio:</h3><p>Matteo Bunino earned a MSc in Data Science and Computer Engineering from both the Polytechnic University of Turin (Italy) and EURECOM (France), in the context of a double degree program. …”
Publicado 2023
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112653por Fernández Velázquez, Juan Antonio“…En el caso de Sinaloa, el consumo de opio se vinculaba con individuos de procedencia extranjera (chinos) en el contexto de la persecución, con tintes racistas, fomentada por el gobierno de Elías Calles, mientras que la mariguana circulaba en las calles de las principales ciudades de la entidad, debido a la existencia de un mercado interno.Palabras clave: Drogas, Tráfico, Consumo, Marginalidad, Cotidianidad, Mercado interno From the drugstore to the streets: traffic and consumption of drugs in Sinaloa, MexicoSummaryThe traffic and consumption of narcotics in Mexico has had different facets during its regulation. …”
Publicado 2017
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112654“…It was noteworthy that LP, BC, and their combination increased the relative abundances of carbohydrate metabolism, energy metabolism, cofactors, and vitamin metabolism, decreasing the relative abundances of amino acid metabolism and drug resistance: antimicrobial. …”
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112655por Lau, Edmond Y., Enright, Heather A., Lao, Victoria, Malfatti, Michael A., Mayer, Brian P., Williams, Audrey M., Valdez, Carlos A.“…The ability of the cyclodextrin-oxime construct 6-OxP-CD to bind and degrade the nerve agents Cyclosarin (GF), Soman (GD) and S-[2-[Di(propan-2-yl)amino]ethyl] O-ethyl methylphosphonothioate (VX) has been studied using (31)P-nuclear magnetic resonance (NMR) under physiological conditions. …”
Publicado 2023
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112656por van Vliet, Stephan, Blair, Amanda D., Hite, Lydia M., Cloward, Jennifer, Ward, Robert E., Kruse, Carter, van Wietmarchsen, Herman A., van Eekeren, Nick, Kronberg, Scott L., Provenza, Frederick D.“…The studied bison meat—irrespective of finishing practice—contained favorable omega 6:3 ratios (< 3.2), and amino acid and vitamin profiles. Our study represents one of the deepest meat profiling studies to date (> 1500 unique compounds), having revealed previously unrecognized differences in animal metabolic health and nutritional composition because of finishing mode. …”
Publicado 2023
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112657por Zhang, Bao-Yuan, Fang, Wen-Hao, Zhu, Rui, Wang, Ning, Yao, Qi, Liu, Hong-Jian, Wan, Ji-Wu, Chen, Yu-Ke, Wang, Qiu-Ju, Zhang, Dong-Ming“…The content of muscle essential amino acids (EAA) reached the maximum in the D46 group; the hepatopancreas EAA content began to decrease significantly in the D31 group (P < 0.05); and the EAA content of the ovary decreased significantly after reaching the maximum value in the D46 group (P < 0.05). …”
Publicado 2023
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112658por Jiang, Yongjia, Peng, Kai, Wang, Qiaojun, Wang, Mianzhi, Li, Ruichao, Wang, Zhiqiang“…This DfrA variant shared 66.47% amino acid sequence identity with DfrA36 and shared ≤51.20% identity with any other previously identified DfrA proteins. …”
Publicado 2023
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112659por Shaufi, Mohd Asrore Mohd, Sieo, Chin Chin, Chong, Chun Wie, Geok Hun, Tan, Omar, Abdul Rahman, Han Ming, Gan, Wan Ho, Yin“…The predicted genes related to carbohydrate and amino acid metabolism were significantly upregulated in ϕP groups compared to non-ϕP groups. …”
Publicado 2023
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112660“…Based on 1) the predicted binding affinities of the NPs to the M(pro), 2) the types and number of interactions with the M(pro) amino acids that are critical for its function, and 3) the desirable pharmacokinetic properties of the NPs, we identified the top 20 candidates that could potentially inhibit the M(pro) protease function. …”
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